Letters in Drug Design & Discovery

Editor-in-Chief:

George Perry
University of Texas
San Antonio, TX
USA

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Most Accessed Articles

Synthesis and Biological Evaluation of Some Novel Thiophene-bearing Quinazoline Derivatives as EGFR Inhibitors open access plus

Volume: 16   Issue: 2
Pp: 102-110
Min Zou, Bo Jin, Yanrong Liu, Huiping Chen, Zhuangli Zhang, Changzheng Zhang, Zhihong Zhao and Liyun Zheng*
DOI: 10.2174/1570180815666180803125935

Benzothiazol Clubbed Imidazol-4-ones as Anti-fungal, Anti-tubercular and Anti-HIV-1 Agents: Their Synthesis and Molecular Docking Study

Volume: 16   Issue: 4
Pp: 382-391
Navin B. Patel*, Asif R. Shaikh, Vatsal M. Patel, Edgar E. Lara-Ramirez and Gildardo Rivera
DOI: 10.2174/1570180815666180712150050

Synthesis, Molecular Modelling and Antibacterial Activity Against Helicobacter pylori of Novel Diflunisal Derivatives as Urease Enzyme Inhibitors

Volume: 16   Issue: 4
Pp: 392-400
Göknil Pelin Coşkun, Teodora Djikic, Sadık Kalaycı, Kemal Yelekçi, Fikrettin Şahin and Ş. Güniz Küçükgüzel*
DOI: 10.2174/1570180815666180627130208

Synthesis of 3-Arylindazole-1-acetic Acids and In Vitro Study of Potential Antibacterial Effect

Volume: 16   Issue: 4
Pp: 401-407
Fauzia Anjum Chattha, Samina Kousar, Mehr-un-Nisa and Munawar Ali Munawar*
DOI: 10.2174/1570180815666180702152259

Novel Tri-substituted Thiazoles Bearing Piperazine Ring: Synthesis and Evaluation of their Anticancer Activity

Volume: 16   Issue: 5
Pp: 547-555
Asaf Evrim Evren*, Leyla Yurttaş, Busra Eksellı and Gulsen Akalın-Cıftcı
DOI: 10.2174/1570180815666180731122118

Coumarinyl Aryl/Alkyl Sulfonates with Dual Potential: Alkaline Phosphatase and ROS Inhibitory Activities: In-Silico Molecular Modeling and ADME Evaluation

Volume: 16   Issue: 3
Pp: 256-272
Uzma Salar, Khalid Mohammed Khan*, Syeda Abida Ejaz, Abdul Hameed, Mariya al-Rashida, Shahnaz Perveen, Muhammad Nawaz Tahir, Jamshed Iqbal* and Muhammad Taha
DOI: 10.2174/1570180815666180327125738

The Development of Tyrosyl-DNA Phosphodyesterase 1 (TDP1) Inhibitors Based on the Amines Combining Aromatic/Heteroaromatic and Monoterpenoid Moieties

Volume: 16   Issue: 5
Pp: 597-605
Evgenii Mozhaitsev, Evgenii Suslov*, Yuliya Demidova, Dina Korchagina, Konstantin Volcho, Alexandra Zakharenko, Inna Vasil'eva, Maksim Kupryushkin, Arina Chepanova, Daniel Moscoh Ayine-Tora, Jóhannes Reynisson, Nariman Salakhutdinov and Olga Lavrik
DOI: 10.2174/1570180816666181220121042

Theoretical Coupling and Stability of Boronic Acid Adducts with Catecholamines

Volume: 16   Issue: 4
Pp: 467-475
Eugeniy Demianenko, Alexey Rayevsky, Marvin A. Soriano-Ursúa* and José G. Trujillo-Ferrara*
DOI: 10.2174/1570180815666180710101604

Potential of Nanoparticles in Combating Candida Infections

Volume: 16   Issue: 5
Pp: 478-491
Faizan Abul Qais, Mohd Sajjad Ahmad Khan, Iqbal Ahmad* and Abdullah Safar Althubiani
DOI: 10.2174/1570180815666181015145224