Mini-Reviews in Medicinal Chemistry

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Ahead of Print Article(s)

Design, Synthesis and Biological Evaluation of Spiro Cyclohexane-1,2- Quinazoline Derivatives as Potent Dipeptidyl Peptidase IV Inhibitors

Volume:17
Yasmin M Syam, Somaia S. Abd El-Karim, Tamer Nasr, Samia A. Elseginy, Manal M. Anwar*, Mohsen M Kamel and Hanan F. Ali

Natural Bioactive New Withanolides

Volume:18
Qian-Qian Xu and Kui-Wu Wang*

Nanomedicine Strategies for Sustained, Controlled and Targeted Treatment of Alzheimer’s Disease

Volume:18
Tian-Jun Ma , Jie Gao, Yan Liu, Jian-Hua Zhuang, Chuan Yin, Peng Li, Lei Mao, Jin Xu , Yi-Xin Xu, Yan-Peng Li , Zhong-Xin Zhao and You Yin*

Marine Natural Product Bis-indole Alkaloid Caulerpin: Chemistry and Biology

Volume:17
Jignesh Lunagariya, Poonam Bhadja, Shenghui Zhong, Rohit Vekariya and Shihai Xu*

Triazolopyrimidines and Thiazolopyrimidines: Synthesis, Anti-HSV-1, Cytotoxicity and Mechanism of Action

Volume:18
Salwa F. Mohamed, Eman M. H. Abbas, Hemat S. Khalaf, Thoraya A. Farghaly* and Dina N. Abd El-Shafy

The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review

Volume:17
Jaya Dwivedi*, Swapnil Sharma, Sonika Jain and Aarti Singh

Theranostic Aspects: Treatment of Cancer by Nanotechnology

Volume:18
Bidisha Sarkar and Priyankar Paira*

Antimicrobial Potential of Benzimidazole Derived Molecules

Volume:17
Yogita Bansal*, Manjinder Kaur and Gulshan Bansal

Back to (non-)Basics: An Update on Neutral and Charge-Balanced Glycosidase Inhibitors

Volume:17
Michela I Simone, Laura Mares, Clothilde Eveleens, Adam McCluskey, Brighid B Pappin, Milton J Kiefel and Todd A Houston*

Anticancer Potential of Thiazole Derivatives: A Retrospective Review

Volume:17
Shweta Jain, Satyanarayan Pattnaik, Kamla Pathak, Sushant Kumar, Devender Pathak, Surendra Jain and Ankur Vaidya*

Medicinal Purposes: Bioactive Metabolites from Marine-derived Organisms

Volume:17
Tingting Li, Ting Ding* and Jianrong Li

Aromatase Inhibitors Evolution as Potential Class of Drugs in the Treatment of Postmenopausal Breast Cancer Women

Volume:17
Stephen Paul Avvaru, Malleshappa N Noolvi*, Tejraj M Aminabhavia and Sudipta Chakraborty

Herbs for Effective Treatment of Diabetes Mellitus: Medicinal Chemistry and Future Therapeutic Options

Volume:17
Farida Hussan, Mohamad Fairuz Yahaya, Seong Lin Teoh and Srijit Das*

A Systematic Review on the Sinomenine Derivatives

Volume:17
Jian Tang*, Aun Raza, Jian Chen and Huaxi Xu

Recent Applications of Triazolopyrimidine-Based Bioactive Compounds in Medicinal and Agrochemical Chemistry

Volume:17
Qu Renyu, Liu Yuchao, W.M. Wishwajith W. kandegama, Chen Qiong* and Yang Guangfu*

A Review of the Pharmacological Properties of 3,4-dihydro-2(1H)- quinolinones

Volume:17
Letitia Meiring, Jacobus P. Petzer and Anél Petzer*

Ornithine Decarboxylase Inhibition: A Strategy to Combat Various Diseases

Volume:17
Priyanshu R. Rai, Rakesh R. Somani* and Pooja S. Kandpile

A Review on Phytochemistry and Pharmacology of Medicinal as well as Poisonous Mushrooms

Volume:17
Diksha Sharma*, Virendra Pratap Singh and Narendra Kumar Singh

Beyond The Therapeutic Effect of rTMS in Alzheimer’s Disease: A Possible Neuroprotective Role of Hippocampal BDNF? : A Minireview

Volume:17
Burak Yulug*, Lütfü Hanoglu, Elmir Ksanmemmedov, Ozge Arıcı Düz, Burcu Polat, Taha Hanoglu, Mehmet Yalçin Günal and Ertugrul Kilic

Development, Potential Anticancer Activity and the Receptor Profile of Different Functionalized 1,3,5-Triazine Derivatives

Volume:17
Mona O. Sarhan, Mohamed A. Motaleb, Ismail T. Ibrahim, Wafaa. A. Zaghary* and Manal M. Anwar*

Ultrasound Assisted One-pot and Sequential Synthesis of 3-methyleneisoindolin- 1-ones and their in vitro Evaluation

Volume:17
Kancharla Suman, Yarlagadda Bharath, V. Anuradha, Mandava V. Basaveswara Rao* and Manojit Pal*

Therapeutic Potential of Alpinia officinarum

Volume:17
David Young*, Manoharan K Pillai and Mohamed Majid

Rational Approaches, Design Strategies, Structure Activity Relationship and Mechanistic Insights for Esterase Inhibitors

Volume:17
Harbinder Singh, Jatinder Vir Singh, Navdeep Kaur, Mohit Sanduja, Gurpreet Singh, Preet Mohinder Singh Bedi and Sahil Sharma*

New Therapeutic Targets and Drugs for the Treatment of Asthma

Volume:17
Mateus Feitosa Alves, Diogo Vilar da Fonsec, Sílvia Adelaide Linhares de Melo, Marcus Tullius Scotti*, Luciana Scotti, Sócrates Golzio dos Santos and Margareth de Fátima Formiga Melo Diniz

Aptamer Oligonucleotides as Potential Therapeutics in Hematologic Diseases

Volume:17
Weibin Li, Meng Zhao, Kaiyu Wang, Huihui Yan and XIaopeng lan*

Synthesis of New Bis-Spiropyrazoles as Antitumor Agents under Ultrasound Irradiation

Volume:17
Naglaa A. Abdel Hafez, Huwaida M. E. Hassaneen, Thoraya A. Farghaly*, Sayed M. Riyadh and Heba S. A. Elzahabi

Synthesis, Anticancer Screening and Molecular Docking Studies of New Heterocycles with Trimethoxyphenyl Scaffold as Combretastatin Analogues

Volume:17
Korany A. Ali*, Naglaa A. Abdel Hafez, Mohamed A. Elsayed, Manal M. Elshahawi, Salwa M. El-Hallouty and Abd El-Galil E. Amr

Cholinesterase Inhibitory Activity of Some semi-Rigid Spiro Heterocycles: POM Analyses and Crystalline Structure of Pharmacophore Site

Volume:17
Taibi Ben Hadda, Oualid Talhi, Artur S.M. Silva, Fatma Sezer Senol, Ilkay Erdogan Orhan, Abdur Rauf , Yahia N. Mabkhot, Khaldoun Bachari , Ismail Warad , Thoraya A. Farghaly *, Ismail I. Althagafi and Mohammad S. Mubarak

Design, Synthesis and Antibacterial Evaluation of Compounds Based on New Benzoxepine-oxime-1,2,3-triazole Hybrid

Volume:17
Naveen Kuntala, Jhonsee Rani Telu, Venkanna Banothu, Sridhar Balasubramanian, Jaya Shree Anireddy and Sarbani Pal*

Medical Therapy for Long QT Syndrome

Volume:17
George Adamos*, Nicoletta Iacovidou and Theodoros Xanthos

The Role of Quinidine in the Pharmacological Therapy of Ventricular Arrhythmias ‘Quinidine

Volume:17
Bojana Bozic*, Teodora Vidonja Uzelac, Aleksandra Kezic and Milica Bajcetic

Substituted Benzamides from Antiinflammatory and p38 Kinase Inhibitors to Antitubercular Activity: Design, Synthesis and Screening

Volume:17
Ravindra Kulkarni, Umakant Mitkari, G Achaiah *, Stefan Laufer, D. V. R .N Bikshapti, V. M Chandrashekar, P. B Gurav , S. J Joshi and V. D Chipade

Dietary Phytochemicals and Endrocrine-related Activities: An Update

Volume:17
Antonella Smeriglio, Marcella Denaro and Domenico Trombetta*

Pharmacological Treatment of Vagal Hyperactivity, a Rare but Potentially Fatal Cause of Sudden Cardiac Death

Volume:17
Pier Paolo Bassareo*, Daniele Cocco, Valentina Bassareo, Bandino Stefano and Giuseppe Mercuro

Chemistry of Heterocyclic Five and Six Membered Enamino Nitriles and Enamino Esters

Volume:16
Moustafa Sherief Moustafa*, Saleh Mohammed Al-Mousawi*, Hesham R. El-Seedi* and Mohamed Hilmy Elnagdi

Recent Development of Oridonin Derivatives with Diverse Pharmacological Activities

Volume:17
Weiyan Cheng, Chuanhui Huang, Weifeng Ma, Xin Tian* and Xiaojian Zhang*

Berberine Derivatives with Different Pharmacological Activities via Structural Modifications

Volume:17
Daipeng Xiao, Zhenbao Liu, Shanshan Zhang, Mi Zhou, Fen He, Ming Zou, Junying Peng, Xiong xie, Yanfei Liu* and Dongming Peng*

Phenothiazine: A Better Scaffold against Tuberculosis

Volume:17
Satheeshkumar Sellamuthu, Mohammad Faizan Bhat, Ashok Kumar and Sushil Kumar Singh

Chemokines and Relevant microRNAs in the Atherogenic Process

Volume:17
Dimitry A Chistiakov, Alexander N Orekhov and Yuri V Bobryshev*

Ellagitannins: Bioavailability, Purification and Biotechnological Degradation

Volume:17
Pedro Aguilar-Zárate, Jorge E. Wong-Paz, Juan J. Buenrostro-Figueroa, Juan A. Ascacio, Juan C. Contreras-Esquivel and Cristóbal N. Aguilar

Aryl Butenes Active against K562 Cells and Lacking Tyrosinase Inhibitory Activity as New Leads in the Treatment of Leukemia

Volume:17
Mehdi El Arbi, Emna Ketata, Aref Neifar, Wafa Mihoubi, Girish K. Gupta, Pascal Pigeon, Siden Top, Ali Gargouri and Gérard Jaouen

Facile and Solvent-free Domino Synthesis of New Quinolidinyl-2,4- thiazolidinones: Antifungal Activity and Molecular Docking

Volume:16
Dnyaneshwar D. Subhedar, Mubarak H. Shaikh, Santosh G. Tupe, Mukund V. Deshpande, Vijay M. Khedkar, Prakash C. Jha and Bapurao B. Shingate

Drug Discovery for Paediatric Chagas Disease

Volume:16
Sreekanth Thota and Carlos M. Morel

Structural Modifications of Matrine-Type Alkaloids

Volume:16
Xiao-hua Cai, Hui Guo and Bing Xie

Chemoprevention of Bladder Cancer: A Mini Review

Volume:16
N Rezakahn Khajeh, C Khoyilar, Y Wu, K Spradling, X Zi and RF Youssef

A Comprehensive Review on the Biological and Pharmacological Activities of Rhodanine Based Compounds for Research and Development of Drugs

Volume:16
Jiachun Liu, Yan-Ling Wu, Huri Piao, Xiaoyin Zhao, Wen Zhang, Yanli Wang and Minrui Liu

Small Molecular as SIRT Modulators

Volume:16
Lei Yao, Xiangming Xu and Kai Chen

A Review of Molecular Predictors of Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer

Volume:16
Stephan Degener, Douglas A. Mata, Ramy Youssef, Daniel Gödde, Zafer Tandogdu, Stephan Roth and Friedrich-Carl von Rundstedt

Synthetic and Natural Lipase Inhibitors

Volume:16
Ewa Białecka-Florjańczyk, Agata Urszula Fabiszewska, Jolanta Krzyczkowska and Alina Kuryłowicz

Tailored Mesoporous Silica Nanoparticles for Controlled Drug Delivery: Platform Fabrication, Targeted Delivery, and Computational Design and Analysis

Volume:16
Xiaodong She, Lijue Chen, Zhifeng Yi, Chengpeng Li, Canzhong He, Chunfang Feng, Tao Wang, Sarah Shigdar, Wei Duan and Lingxue Kong

Controversies Related to Diabetes and Risk of Bladder Cancer

Volume:15
Kyle Spradling and Ramy F. Youssef