Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Abstract Ahead of Print

Discovery of novel substituted N-(6-Chloro-3-cyano-4-phenyl-4H-chromen-2-yl)-2-(4-chloro-phenoxy)-acetamide for biphasic anticancer and anticonvulsant activities

Volume:15
Divya Chauhan*, Syed Riaz Hashim, Priyanka Rani, Sushil Kumar, Navratan Shrimal, Divya Shastri and Vinit Raj

Study on the interaction of 1,5-diaryl pyrrole derivatives with α-glucosidase; synthesis, molecular docking, and kinetic study

Volume:15
Tadesse Bekele Tafesse, Ebrahim Saeedian Moghadam, Mohammed Hussen Bule, Mohammad Ali Faramarzi, Mohammad Abdollahi and Mohsen Amini*

Anti-Cholinesterase Activity of Chalcone Derivatives: Synthesis, In Vitro Assay and Molecular Docking Study

Volume:15
Florentinus D.O. Riswanto, Mira S.A. Rawa, Vikneswaran Murugaiyah, Nurul H. Salin, Enade P. Istyastono, Maywan Hariono and Habibah A. Wahab*

Antitumor effect of zwitterions of imidazolium derived from L- methionine in BALB/c mice with lymphoma L5178Y

Volume:15
Karen C. Vargas-Castro, Ana M. Puebla Pérez, Irma I. Rangel-Salas, Jorge I. Delgado-Saucedo, José B. Pelayo-Vázquez, Elvia Becerra-Martínez, A. Aarón Peregrina-Lucano, Raul R. Quiñonez-Lopez, Gabriela J. Soltero-Reinoso and Sara A. Cortes-Llamas*

N-alpha-Aminoacyl Colchicines as Promising Anticancer Agents

Volume:15
Ana Marzo-Mas, Laura Conesa-Milián, Sam Noppen, Sandra Liekens, Eva Falomir*, Juan Murga, Miguel Carda and J. Alberto Marco

Design of Arylsulfonylhydrazones as Potential FabH Inhibitors: Synthesis, Antimicrobial Evaluation and Molecular Docking

Volume:15
Thais Batista Fernandes, Natanael Dante Segretti, Felipe Rebello Lourenço, Thalita Marcílio Cândido, André Rolim Baby, Euzébio Guimarães Barbosa and Roberto Parise-Filho*

A Study on Synthesis and Antioxidant Activity Comparison of Novel Stilbenebenzamide Compounds

Volume:15
Aleksandra Kładna, Paweł Berczyński, Oya Bozdağ Dündar, Irena Kruk, Beyza Torun and Hassan Y. Aboul-Enein*

NMR: From molecular mechanism to its application in medical care

Volume:15
Zhenhong Zhang, Xiaohong Meng, Wei Cui, Syed Sayeed Ahmad, Mohammad A. Kamal and Jinguo Zhang*

Activity Of (-)-Camphene Derivatives Against Mycobacterium tuberculosis In Acidic pH

Volume:15
Hayalla Corrêa de Carvalho, Andressa Lorena Ieque, Tamires Leite Valverde, Vanessa Pietrowski Baldin, Jean Eduardo Meneguello, Paula Aline Zanetti Campanerut-Sá, Fábio Vandresen, Luciana Dias Ghiraldi Lopes, Mariana Regina Passos Souza, Nathally Claudiane de Souza Santos, Vera Lucia Dias Siqueira, Katiany Rizzieri Caleffi-Ferracioli, Regiane Bertin Lima Scodro and Rosilene Fressatti Cardoso*

An increasing role of polyphenols as novel therapeutics for Alzheimer’s: A review

Volume:15
Nasiara Karim, Haroon Khan*, Imran Khan, Ouyang Guo, Eduardo Sobarzo Sanchez, Luca Rastrelli and Mohammad Amjad Kamal

Therapeutic effects of Ziziphus jujuba Mill. fruit in traditional and modern medicine: a review

Volume:15
Zahra Sobhani , Sara Nikoofal-Sahlabadi, Mohammad Sadegh Amiri, Mahin Ramezani, Seyed Ahmad Emami and Amirhossein Sahebkar*

Synthesis, characterization, antioxidant activity of β-diketonates, and effects of coordination to copper(II) ion on their activity: DNA, BSA interactions and molecular docking study

Volume:15
Nenad Joksimović, Jelena Petronijević, Nenad Janković, Marijana Kosanić, Dušan Milivojević, Milan Vraneš, Aleksandar Tot and Zorica Bugarčić*

Synthesis and Biological Evaluation of matrine derivatives as a Novel Family of Potential Anticancer Agents

Volume:15
Jing Wang, Hang Liu, Xiao-Bin Zhuo, Guang-Ming Ye and Qing-Jie Zhao

New Approaches in Sensing and Targeting Bacterial rRNA A-site

Volume:15
Preethi Parameswaran, Nihar Ranjan* and S.J.S. Flora*

Dairy Safety Prediction Based on Machine Learning Combined with Chemicals

Volume:15
Jiahui Chen, Guangya Zhou, Jiayang Xie, Minjia Wang, Yanting Ding, Shuxian Chen, Sijing Xia, Xiaojun Deng*, Qin Chen* and Bing Niu*

Applications of machine learning methods in predicting nuclear receptors and their families

Volume:15
Zi-Mei Zhang, Zheng-Xing Guan, Fang Wang, Dan Zhang and Hui Ding*

Recent Advance in Predicting Subcellular Localization of Mycobacterial Protein with Machine Learning Methods

Volume:15
Shi-Hao Li, Zheng-Xing Guan, Dan Zhang, Zi-Mei Zhang, Jian Huang, Wuritu Yang* and Hao Lin*

The Assessment of Interleukin-18 on the Risk of Coronary Heart Disease

Volume:15
Weiju Sun, Ying Han, Shuo Yang, He Zhuang, Jingwen Zhang, Liang Cheng* and Lu Fu*

iATP: A sequence based method for identifying anti-tubercular peptides

Volume:15
Wei Chen*, Pengmian Feng and Fulei Nie

Fluoroquinolone-3-carboxamide amino acid conjugates: Synthesis, antibacterial properties and molecular modeling studies

Volume:15
Riham M. Bokhtia, Siva S. Panda*, Adel S. Girgis, Hitesh H. Honkanadavar, Tarek S. Ibrahim, Amany M. M. Al-Mahmoudy, Riham F. George, Mona T. Kashef, Walid Fayad, Rajeev Sakhuja and Eatedal H. Abdel-Aal

The antioxidant, anticarcinogenic and antimicrobial properties of Verbascum thapsus L.

Volume:15
Saman Mahdavi*, Morteza Amiradalat, Marzieh Babashpour, Hosein Sheikhlooei and Mohammad Miransari

Improvement of the Anticancer Activity of Chlorambucil and Ibuprofen via Calix[4]arene Conjugates

Volume:15
Luis D. Pedro-Hernández, Ulises Organista-Mateos, Luis Isaac Allende-Alarcón, Elena Martínez-Klimova*, Teresa Ramírez-Ápan and Marcos Martínez-García

Novel benzoxazin-3-one derivatives: Design, synthesis, molecular modeling, anti-HIV-1 and integrase inhibitory assay

Volume:15
Mahdieh Safakish, Zahra Hajimahdi, Rouhollah Vahabpour, Rezvan Zabihollahi and Afshin Zarghi*

ROS Inhibitory Activity and Cytotoxicity Evaluation of Benzoyl, Acetyl, Alkyl Ester, and Sulfonate Ester Substituted Coumarin Derivatives

Volume:15
Uzma Salar, Khalid Mohammed Khan*, Almas Jabeen, Aisha Faheem, Farwa Naqvi, Shakil Ahmed, Erum Iqbal, Farman Ali, Kanwal and Shahnaz Perveen

Methoxychalcones: Effect of Methoxyl Group toward Antifungal, Antibacterial and Antiproliferative Activities

Volume:15
Beatriz C. Marques, Mariana B. Santos, Daiane B. Anselmo, Diego A. Monteiro, Eleni Gomes, Marilia F. C. Saiki, Paula Rahal, Pedro L. Rosalen, Janaina C. O. Sardi and Luis O. Regasini

Synthetic Dihydropyridines as Novel Antiacanthamoebic Agents

Volume:15
Ayaz Anwar*, Ruqaiyyah Siddiqui, Abdul Hameed, Muhammad Raza Shah and Naveed Ahmed Khan

Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated / N-Tiophosphorylated Tacrine

Volume:15
Maja Przybyłowska, Iwona Inkielewicz-Stepniak, Szymon Kowalski, Krystyna Dzierzbicka*, Sebastian Demkowicz and Mateusz Daśko