Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Most Accessed Articles

Cystic Fibrosis Revisited – a Review Study

Volume: 13   Issue: 2
Pp: 102-109
Blanka Klimova, Kamil Kuca, Michal Novotny and Petra Maresova
DOI: 10.2174/1573406412666160608113235

USP7: Target Validation and Drug Discovery for Cancer Therapy

Volume: 14   Issue: 1
Pp: 3-18
Jin Zhou*, Jinzheng Wang, Chao Chen, Haoliang Yuan, Xiaoan Wen* and Hongbin Sun*
DOI: 10.2174/1573406413666171020115539

Synthesis and Biological Evaluation of Acridine/Acridone Analogs as Potential Anticancer Agents

Volume: 15   Issue: 7
Pp: 729-737
Monika Gensicka-Kowalewska, Mirosława Cichorek, Anna Ronowska, Milena Deptuła, Ilona Klejbor and Krystyna Dzierzbicka*
DOI: 10.2174/1573406414666181015145120

Novel Amide Derivatives as Potent Tyrosinase Inhibitors; In-vitro, In-vivo Antimelanogenic Activity and Computational Studies

Volume: 15   Issue: 7
Pp: 715-728
Anser Ali, Zaman Ashraf, Muhammad Rafiq, Ajeet Kumar, Farukh Jabeen, Goon Joon Lee, Fahad Nazir, Mushtaq Ahmed, Myungchull Rhee and Eun Ha Choi*
DOI: 10.2174/1573406415666190319101329

Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity

Volume: 15   Issue: 6
Pp: 602-623
Ahmed M. Abdelaziz, Sarah Diab, Saiful Islam, Sunita K.C. Basnet, Benjamin Noll, Peng Li, Laychiluh B. Mekonnen, Jingfeng Lu, Hugo Albrecht, Robert W. Milne, Cobus Gerber, Mingfeng Yu * and Shudong Wang*
DOI: 10.2174/1573406415666181219111511

Design, Synthesis, and Biological Evaluation of Novel Thiazolyl Substituted Bis-pyrazole Oxime Derivatives with Potent Antitumor Activities by Selectively Inducing Apoptosis and ROS in Cancer Cells

Volume: 15   Issue: 7
Pp: 743-754
Biao Xiong, Shi Chen, Peng Zhu, Meiling Huang, Weijie Gao, Rui Zhu, Jianqiang Qian, Yanfu Peng, Yanan Zhang, Hong Dai * and Yong Ling*
DOI: 10.2174/1573406414666180827112724

Discovery and Optimization of a Series of Sulfonamide Inverse Agonists for the Retinoic Acid Receptor-Related Orphan Receptor-α

Volume: 15   Issue: 6
Pp: 676-684
Christelle Doebelin, Yuanjun He, Sean Campbell, Philippe Nuhant, Naresh Kumar, Marcel Koenig, Ruben Garcia-Ordonez, Mi Ra Chang, William R. Roush, Li Lin, Susan Kahn, Michael D. Cameron, Patrick R. Griffin, Laura A. Solt* and Theodore M. Kamenecka*
DOI: 10.2174/1573406415666190222124745

Evaluation of Cytotoxic Potentials of Some Isoindole-1, 3-Dione Derivatives on HeLa, C6 and A549 Cancer Cell Lines

Volume: 16   Issue: 1
Pp: 69-77
Ayse Tan, Ayse Sahin Yaglioglu, Nurhan Horasan Kishali*, Ertan Sahin and Yunus Kara*
DOI: 10.2174/1573406415666181206115638