Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

Back

Become EABM
Become Reviewer

Editorial [Hot Topics: New Trends in Micro- and Nano-systems Development for Pharmaceutical Actives Release] promotion: free to download

Volume:8   Issue: 4
Pp: 515-515
Lucia Martin-Banderas
DOI: 10.2174/157340612801216229

Synthesis of a Biodegradable Magnetic Nanomedicine Based on the Antitumor Molecule Tegafur

Volume:8   Issue: 4
Pp: 516-523
Jose L. Arias, Eva Saez-Fernandez, Margarita Lopez-Viota, Rafael A. Biedma-Ortiz and Mª Adolfina Ruiz
DOI: 10.2174/157340612801216373

Monodisperse Nanoparticles from Self-Assembling Amphiphilic Cyclodextrins: Modulable Tools for the Encapsulation and Controlled Release of Pharmaceuticals

Volume:8   Issue: 4
Pp: 524-532
Alejandro Mendez-Ardoy, Marta Gomez-Garcia, Annabelle Geze, Jean-Luc Putaux, Denis Wouessidjewe, Carmen Ortiz Mellet, Jacques Defaye, Jose M. Garcia Fernandez and Juan M. Benito
DOI: 10.2174/157340612801216265

Use of Flow Focusing® Technology to Produce Tobramycin-Loaded Plga Microparticles for Pulmonary Drug Delivery

Volume:8   Issue: 4
Pp: 533-540
Lucia Martin-Banderas, Maria Angeles Holgado, Josefa Alvarez-Fuentes and Mercedes Fernandez- Arevalo
DOI: 10.2174/157340612801216409

Preparation, Chemical and Electrical Characterizations of Lipid Nanoparticles Loaded with Dihydroxybenzophenone

Volume:8   Issue: 4
Pp: 541-548
Hierrezuelo Jesus, Benavente Juana, Lopez–Romero Juan Manuel, Martinez de Yuso Maria del Valle and Rodriguez–Castellon Enrique
DOI: 10.2174/157340612801216238

Editorial [Hot Topic: Calcium Metabolism and Treatment of Hypercalcemia] promotion: free to download

Volume:8   Issue: 4
Pp: 549-550
Franco Lumachi
DOI: 10.2174/157340612801216175

Diagnosis of Alterations of Serum Calcium Metabolism

Volume:8   Issue: 4
Pp: 551-555
Franco Lumachi, Piero Cappelletti, Renato Tozzoli, Stafano M.M. Basso, Giovanni Luisetto and Valentina Camozzi
DOI: 10.2174/157340612801216139

Treatment of Chronic Hypercalcemia

Volume:8   Issue: 4
Pp: 556-563
Valentina Camozzi, Giovanni Luisetto, Stefano M.M. Basso, Piero Cappelletti, Renato Tozzoli and Franco Lumachi
DOI: 10.2174/157340612801216355

Treatment of Acute Hypercalcemia

Volume:8   Issue: 4
Pp: 564-568
Stafano M.M. Basso, Franco Lumachi, Fabiana Nascimben, Giovanni Luisetto and Valentina Camozzi
DOI: 10.2174/157340612801216382

New Adamantane Derivatives with Sigma Affinity and Antiproliferative Activity

Volume:8   Issue: 4
Pp: 569-586
Stefanos Riganas, Ioannis Papanastasiou, George B. Foscolos, Andrew Tsotinis, Kostas Dimas, Vassilios N. Kourafalos, Andreas Eleutheriades, Vassilios I. Moutsos, Humaira Khan, Prassa Margarita, Stavroula Georgakopoulou, Angeliki Zaniou, Maria Theodoropoulou, Athanasios Mantelas, Stavroula Pondiki and Alexandre Vamvakides
DOI: 10.2174/157340612801216201

Design, Synthesis and Antiproliferative Activity of 2-Acetamidothiazole-5- carboxamide Derivatives

Volume:8   Issue: 4
Pp: 587-594
Wukun Liu, Jinpei Zhou, Yu Zheng, Fan Qi, Huibin Zhang, Hai Qian, Jing Wang, Yanhua Cheng and Ronald Gust
DOI: 10.2174/157340612801216418

Differences in Vanadocene Dichloride and Cisplatin Effect on MOLT-4 Leukemia and Human Peripheral Blood Mononuclear Cells

Volume:8   Issue: 4
Pp: 615-621
Radim Havelek, Pavel Siman, Jana Cmielova, Alena Stoklasova, Jirina Vavrova, Jaromir Vinklarek, Jiri Knizek and Martina Rezacova
DOI: 10.2174/157340612801216364

The Preformulation Stability Studies of a Proline Prodrug of Methotrexate

Volume:8   Issue: 4
Pp: 622-628
Ann Stephenson, Zhiqian Wu and Xudong Yuan
DOI: 10.2174/157340612801216166

Synthesis, In Vitro and In Silico NS5B Polymerase Inhibitory Activity of Benzimidazole Derivatives

Volume:8   Issue: 4
Pp: 629-635
Vaishali M. Patil, Gurukumar K. R., Maksim Chudayeu, Satya Prakash Gupta, Subeer Samanta, Neeraj Masand and Neerja Kaushik-Basu
DOI: 10.2174/157340612801216120

Computational Approaches to Improve Aggrecanase-1 Inhibitory Activity of (4-keto) Phenoxy) Methyl Biphenyl-4-sulfonamide: Group Based QSAR and Docking Studies

Volume:8   Issue: 4
Pp: 673-682
Ponnurengam Malliappan Sivakumar, Naga Vignesh Selvaraj, G. Ramesh, J. Mohanapriya, Veluchamy Prabhawathi and Mukesh Doble
DOI: 10.2174/157340612801216247

Synthesis and Biological Evaluation of Naloxone and Naltrexone-Derived Hybrid Opioids

Volume:8   Issue: 4
Pp: 683-689
Bahman E. Nassim and Ming-Lei Wang
DOI: 10.2174/157340612801216193

In vitro Synergy Testing of Anidulafungin with Fluconazole, Tioconazole, 5-Flucytosine and Amphotericin B against some Candida spp.

Volume:8   Issue: 4
Pp: 690-698
Antonio Rosato, Monica Piarulli, Brigida Immacolata Pia Schiavone, Maria Teresa Montagna, Giuseppina Caggiano, Marilena Muraglia, Addolorata Carone, Carlo Franchini and Filomena Corbo
DOI: 10.2174/157340612801216184

Synthesis of Novel 4-Aryl-1,2,3,4-tetrahydroisoquinolines as Probes for Dopamine Receptor Ligands

Volume:8   Issue: 4
Pp: 699-704
Gianfabio Giorgioni, Dario Ambrosini, Giovanni Filippo Palmieri, Barbara Costa, Antonio Di Stefano and Claudia Martini
DOI: 10.2174/157340612801216292

Acylhydrazide Schiff Bases: DPPH Radical and Superoxide Anion Scavengers

Volume:8   Issue: 4
Pp: 705-710
Khalid Mohammed Khan, Muhammad Taha, Farzana Naz, Salman Siddiqui, Sajjad Ali, Fazal Rahim, Shahnaz Perveen and M. Iqbal Choudhary
DOI: 10.2174/157340612801216111

Synthesis and Biological Evaluation of a Series of 6,7-dimethoxy-1-(3,4- dimethoxybenzyl)-2-substituted Tetrahydroisoquinoline Derivatives

Volume:8   Issue: 4
Pp: 711-716
Zhi-hong Zou, Xiao-bu Lan, Chun-lei Tang, Xiao-yun Zhu, Bao-min Liu, Hai Qian, Wen-long Huang and Yun-man Li
DOI: 10.2174/157340612801216337

Synthesis and 188Re Radiolabelling of Dendrimer Polyamide Amine (PAMAM) Folic Acid Conjugate

Volume:8   Issue: 4
Pp: 727-731
Wei Cui, Yuanqing Zhang, Xiaoping Xu and Yu-Mei Shen
DOI: 10.2174/157340612801216256

In Vitro Antibacterial and Antifungal Activity of Salicylanilide Pyrazine-2- carboxylates

Volume:8   Issue: 4
Pp: 732-741
Martin Kratky, Jarmila Vinsova and Vladimir Buchta
DOI: 10.2174/157340612801216346

Design, Synthesis and Multidrug Resistance Reversal Activity Evaluation of 8-Oxocoptisine Derivatives

Volume:8   Issue: 4
Pp: 742-748
Jian Bo Wu, Fan Lei, Xiang Juan Cui, Yun He, Li Hai, Juan Zhang and Yong Wu
DOI: 10.2174/157340612801216148

Serum Specific Vasopressin-Degrading Activity is Related to Blood Total Cholesterol Levels in Men but not in Women

Volume:8   Issue: 4
Pp: 749-752
Ramirez-Exposito Maria Jesus, Arrazola Marcelina, Carrera-Gonzalez Maria Pilar, Arias de Saavedra Jose Manuel, Sanchez-Agesta Rafael, Mayas Maria Dolores and Martinez-Martos Jose Manuel
DOI: 10.2174/157340612801216328

Prodrug Strategies in Ocular Drug Delivery

Volume:8   Issue: 4
Pp: 753-768
Megha Barot, Mahuya Bagui, Mitan R. Gokulgandhi and Ashim K. Mitra
DOI: 10.2174/157340612801216283