Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Norlichexanthone Isolated from Fungus P16 Promotes the Secretion and Expression of Adiponectin in Cultured ST-13 Adipocytes

Volume:7   Issue: 4
Pp: 250-256
Megumi Ikeda, Yoshiko Kurotobi, Aiko Namikawa, Sachi Kuranuki, Nobuyasu Matsuura, Mayumi Sato, Yasuhiro Igarashi, Teiji Nakamura and Tsutomu Oikawa
DOI: 10.2174/157340611796150950

A New Model for Portal Protein Profile Analysis in Course of Ileal Intraluminal Bile Acid Infusion Using an In Situ Perfused Rat Intestine

Volume:7   Issue: 4
Pp: 257-264
Marco Montagnani, Matvey Tsivian, Flavia Neri, Ido Ben Zvi, Irina Mantovani, Paolo Nanni, Marco Benevento, Patrizia Simoni, Antonella Marangoni, Milena Pariali, Romana Fato, Christian Bergamini, Serena Leoni, Francesco Azzaroli, Giuseppe Mazzella, Bruno Nardo, Enrico Roda and Rita Aldini
DOI: 10.2174/157340611796150978

Novel Folate-Hydroxamate Based Antimetabolites: Synthesis and Biological Evaluation

Volume:7   Issue: 4
Pp: 265-274
Marta P. Carrasco, Eva A. Enyedy, Natalia I. Krupenko, Sergey A. Krupenko, Elisa Nuti, Tiziano Tuccinardi, Salvatore Santamaria, Armando Rossello, Adriano Martinelli and M. Amelia Santos
DOI: 10.2174/157340611796150923

An Insight of Novel Pharmacological Therapies in Hypertrophic Cardiomyopathy

Volume:7   Issue: 4
Pp: 275-285
Esteban Orenes-Pinero, Diana Hernandez-Romero, Eva Jover, Gonzalo de la Morena, Mariano Valdes and Francisco Marin
DOI: 10.2174/157340611796150941

Synthesis and Cytotoxic Evaluation of Novel Symmetrical Taspine Derivatives as Anticancer Agents

Volume:7   Issue: 4
Pp: 286-294
Jie Zhang, Yanmin Zhang, Xiaoyan Pan, Sicen Wang and Langchong He
DOI: 10.2174/157340611796150914

Design, Synthesis of Novel Quinazolone Alkaloids Derivatives as Potential Antitumor Agents

Volume:7   Issue: 4
Pp: 295-300
Youguang Zheng, Min Sun, Yi Liu, Mingdong Li and Min Ji
DOI: 10.2174/157340611796150987

Modeling of HIV-1 TAR RNA-Ligand Complexes

Volume:7   Issue: 4
Pp: 301-308
Petar M. Mitrasinovic, Jyoti S. Tomar, Maya S. Nair and Ritu Barthwal
DOI: 10.2174/157340611796150932

Computer-Aided Design, Synthesis, and Biological Activity Evaluation of Potent Fusion Inhibitors Targeting HIV-1 gp41

Volume:7   Issue: 4
Pp: 309-316
Jian Jun Tan, Bin Zhang, Xiao Jing Cong, Lei Fu Yang, Bin Liu, Ren Kong, Zhi Yao Kui, Cun Xin Wang and Li Ming Hu
DOI: 10.2174/157340611796150905

Comparative Antioxidant Properties of Some Gabaergic Phenols and Related Compounds, Determined for Homogeneous and Membrane Systems

Volume:7   Issue: 4
Pp: 317-324
Leticia Delgado Marin, Mariela Sanchez-Borzone and Daniel A. Garcia
DOI: 10.2174/157340611796150969

Prediction of Theoretical Physicochemical Properties and One-Pot Synthesis of Bis-Azetidinones by [2+2] Ketene – Imine Cycloaddition in the Presence of Montmorillonite

Volume:7   Issue: 4
Pp: 325-332
Ramakanth Pagadala, Jyotsna S. Meshram, Himani N. Chopde, Venkateshwarlu Jetti, Uppalaiah Kusampally and V. Udayini
DOI: 10.2174/157340611796150897