Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Synthesis and Cellular Pharmacology Studies of a Series of 2-amino-3-aroyl-4-substituted Thiophene Derivatives

Volume:6   Issue: 6
Pp: 329-343
Romeo Romagnoli, Pier Giovanni Baraldi, Maria Giovanna Pavani, Olga Cruz-Lopez, Ernest Hamel, Jan Balzarini, Eleonora Brognara, Cristina Zuccato and Roberto Gambari
DOI: 10.2174/157340610793563974

Synthesis, Testing and Structure-Activity Studies on a Library of 5-HT4 Ligands

Volume:6   Issue: 6
Pp: 344-354
Amir Hanna-Elias, David T. Manallack, Alla Levit, William Nguyen, Fadi Ayad, Glen Perera, Marina Shapiro, Helen R. Irving, Ian M. Coupar and Magdy N. Iskander
DOI: 10.2174/157340610793563965

New Synthesis of Tic-Hydantoins Sigma-1 Ligands and Pharmacological Evaluation on Cocaine-Induced Stimulant Effects

Volume:6   Issue: 6
Pp: 355-373
M. Toussaint, M.-A. Debreu-Fontaine, T. Maurice and P. Melnyk
DOI: 10.2174/157340610793563956

A Novel Access to Arylated and Heteroarylated Beta-Carboline Based PDE5 Inhibitors

Volume:6   Issue: 6
Pp: 374-387
Nermin S. Ahmed, Bernard D. Gary, Gary A. Piazza, Heather N. Tinsley, Stefan Laufer and Ashraf H. Abadi
DOI: 10.2174/157340610793563992

Anticancer Activity of the Ascidian Polyclinum Indicum against Cervical Cancer Cells (HeLa) Mediated through Apoptosis Induction

Volume:6   Issue: 6
Pp: 396-405
Rajaian Pusphabai Rajesh, Maniramakrishnan Santhana Ramasamy and Annappan Murugan
DOI: 10.2174/157340610793564009