Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Synthesis and Antimalarial Activity of New Amino Analogues of Amodiaquine

Volume:4   Issue:5
Pp: 407-425
E. Paunescu, S. Susplugas, E. Boll, R. A. Varga, E. Mouray, P. Grellier and P. Melnyk
DOI: 10.2174/157340608785700153

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Dihydroethanoanthracene Derivatives Reverse In Vitro Quinoline Resistance in Plasmodium falciparum Malaria

Volume:4   Issue:5
Pp: 426-437
Maud Henry, Sandrine Alibert, Meili Baragatti, Joel Mosnier, Eric Baret, Remy Amalvict, Eric Legrand, Thierry Fusai, Jacques Barbe, Christophe Rogier, Jean-Marie Pages and Bruno Pradines
DOI: 10.2174/157340608785700234

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N,N-Bis(trifluoromethylquinolin-4-yl)diamino Alkanes: Synthesis and Antimalarial Activity

Volume:4   Issue:5
Pp: 438-445
Joseph L. Kgokong, Gilbert M. Matsabisa, Peter P. Smith and Jaco C. Breytenbach
DOI: 10.2174/157340608785700216

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Synthesis and Antimalarial Activity of Novel Side Chain Modified Antimalarial Agents Derived from 4-Aminoquinoline

Volume:4   Issue:5
Pp: 446-456
V. Raja Solomon, W. Haq, M. Smilkstein, Kumkum Srivastava, S. Rajakumar, Sunil K. Puri and S. B. Katti
DOI: 10.2174/157340608785700207

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Synthesis of 2-Methyl N10-Substituted Acridones as Selective Inhibitors of Multidrug Resistance (MDR) Associated Protein in Cancer Cells

Volume:4   Issue:5
Pp: 457-465
Y. C. Mayur, Osman Ahmad, V. V.S. Rajendra Prasad, M. N. Purohit, N. Srinivasulu and S. M. Shanta Kumar
DOI: 10.2174/157340608785700180

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Synthesis and Evaluation of 1-Benzhydryl-sulfonyl-piperazine Derivatives as Inhibitors of Tumor Growth and Tumor Angiogenesis of Mouse Ehrlich Ascites Tumor In Vivo

Volume:4   Issue:5
Pp: 466-472
C. S. Ananda Kumar, H. Chandru, A. C. Sharada, N. R. Thimmegowda, S. B. Benaka Prasad, M. Karuna Kumar and K. S. Rangappa
DOI: 10.2174/157340608785700171

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Synthesis, Antimycobacterial Activities and Phototoxic Evaluation of 5H-thiazolo[3,2-a]quinoline-4-carboxylic Acid Derivatives

Volume:4   Issue:5
Pp: 482-491
Murugesan Dinakaran, Palaniappan Senthilkumar, Perumal Yogeeswari, Arnab China, Valakunja Nagaraja and Dharmarajan Sriram
DOI: 10.2174/157340608785700225

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Structure-Activity Relationship Study of a Series of N-Substituted Piperazinyl-Fluoroquinolones as Anti-Helicobacter pylori Agents

Volume:4   Issue:5
Pp: 498-502
A. Foroumadi, M. Safavi, S. Emami, F. Siavoshi, S. Najjari, F. Safari and A. Shafiee
DOI: 10.2174/157340608785700162

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Synthesis of N3-Substituted Thymidine Analogues for Measurement of Cellular Kinase Activity

Volume:4   Issue:5
Pp: 503-512
P. Ghosh, A. Pal, A. Shavrin, W. Bornmann, J. G. Gelovani and M. M. Alauddin
DOI: 10.2174/157340608785700252

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