Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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2(3)-Aryl-thio(oxy)-methylquinoxaline Derivatives: A New Class of P-Glycoprotein-Mediated Drug Efflux Inhibitors

Volume:4   Issue:3
Pp: 194-205
Antonio Carta, Sandra Piras, Giuseppe Paglietti, Sabrina Pricl, Paolo La Colla, Bernardetta Busonera and Roberta Loddo
DOI: 10.2174/157340608784325197

CDK9 a Potential Target for Drug Development

Volume:4   Issue:3
Pp: 210-218
Fernanda Canduri, Patricia Cardoso Peres, Rafael Andrade Caceres and Walter Filgueira de Azevedo Jr.
DOI: 10.2174/157340608784325205

Aqueous Extract of Arbutus unedo Inhibits STAT1 Activation in Human Breast Cancer Cell Line MDA-MB-231 and Human Fibroblasts Through SHP2 Activation

Volume:4   Issue:3
Pp: 219-228
S. Mariotto, A. R. Ciampa, A. Carcereri de Prati, E. Darra, S. Vincenzi, M. Sega, E. Cavalieri, K. Shoji and H. Suzuki
DOI: 10.2174/157340608784325179

Synthesis, Evaluation and QSAR Studies of 16-(4 & 3,4-Substituted) Benzylidene Androstene Derivatives as Anticancer Agents

Volume:4   Issue:3
Pp: 229-236
S. Dubey, P. Kaur, D. P. Jindal, Y. D. Satyanarayan and P. Piplani
DOI: 10.2174/157340608784325133

Quantitative Structure – ActivityRelationship (QSAR) of N-Arylsubstituted Hydroxamic Acids as Inhibitors of Human Adenocarinoma Cells A431

Volume:4   Issue:3
Pp: 237-243
Ram Prakash Rajwade, Rama Pande, K. P. Mishra, Amit Kumar and B. N. Pandey
DOI: 10.2174/157340608784325106

β-Cyclodextrin Conjugates with Glucose Moieties Designed as Drug Carriers: Their Syntheses, Evaluations Using Concanavalin A and Doxorubicin, and Structural Analyses by NMR Spectroscopy

Volume:4   Issue:3
Pp: 244-255
Yoshiki Oda, Natsumi Kobayashi, Takashi Yamanoi, Kaname Katsuraya, Keiko Takahashi and Kenjiro Hattori
DOI: 10.2174/157340608784325098

Expression of mRNA of Neurotrophic Factors and their Receptors are Significantly Altered After Subchronic Ketamine Treatment

Volume:4   Issue:3
Pp: 256-263
Axel Becker, Gisela Grecksch, Herbert Schwegler and Thomas Roskoden
DOI: 10.2174/157340608784325124

Live Yeast Cell Derivative Induces c-fos Expression in THP-1 Monocytes

Volume:4   Issue:3
Pp: 264-272
Andrew Osterburg and Stephen J. Keller
DOI: 10.2174/157340608784325142

Quantitative Structure Activity Analysis of 2-Alkoxydihydrocinnamates as PPARα /γ Dual Agonist

Volume:4   Issue:3
Pp: 273-277
P. Manoj Kumar, R. Hemalatha, S. C. Mahajan, C. Karthikeyan, N. S. Hari Narayana Moorthy and Piyush Trivedi
DOI: 10.2174/157340608784325188

The Effect of Soybean Oil on Glycaemic Control in Goto-Kakizaki Rats,an Animal Model of Type 2 Diabetes

Volume:4   Issue:3
Pp: 293-297
Cristina M. Sena, Teresa Proenca, Elsa Nunes, Maria S. Santos and Raquel M. Seica
DOI: 10.2174/157340608784325115