Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Antileishmanial and Antimalarial Chalcones: Synthesis, Efficacy and Cytotoxicity of Pyridinyl and Naphthalenyl Analogs

Volume:3   Issue:2
Pp: 115-119
C. E. Gutteridge, J. V. Vo, C. B. Tillett, J. A. Vigilante, J. R. Dettmer, S. L. Patterson, K. A. Werbovetz, J. Capers, D. A. Nichols, A. K. Bhattacharjee and L. Gerena
DOI: 10.2174/157340607780059530

Evaluation of Polygonum bistorta for Anticancer Potential Using Selected Cancer Cell Lines

Volume:3   Issue:2
Pp: 121-126
Karuppiah Pillai Manoharan, Daiwen Yang, Annie Hsu and Benny Tan Kwong Huat
DOI: 10.2174/157340607780059495

2-Amino/Azido/Hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines:Synthesis and Pharmacological Evaluation

Volume:3   Issue:2
Pp: 127-134
O. Bruno, C. Brullo, F. Bondavalli, A. Ranise, S. Schenone, M. Tognolini, V. Ballabeni and E. Barocelli
DOI: 10.2174/157340607780059549

Flexible Estrogen Receptor Modulators: Synthesis, Biochemistry and Molecular Modeling Studies for 3-Benzyl-4,6-diarylhex-3-ene and 3,4,6-Triarylhex-3-ene Derivatives

Volume:3   Issue:2
Pp: 135-155
Helena M. Smith, Andrew J. S. Knox, Daniela M. Zisterer, David G. Lloyd and Mary J. Meegan
DOI: 10.2174/157340607780059503

Cellular Pharmacology, Antineoplastic Activity and Low In Vivo Toxicity of a Carboxylato-Bridged Platinum(II) Complex bis(acetato)diammine-bis-μ-acetato diplatinum (II) Dihydrate

Volume:3   Issue:2
Pp: 157-165
Georgi Momekov, Spiro Konstantinov, Margarita Topashka-Ancheva, Adriana Bakalova, Sonja Arpadjan and Margarita Karaivanova
DOI: 10.2174/157340607780059486

Pharmacophore Modeling in Drug Discovery and Development: An Overview

Volume:3   Issue:2
Pp: 187-197
Santosh A. Khedkar, Alpeshkumar K. Malde, Evans C. Coutinho and Sudha Srivastava
DOI: 10.2174/157340607780059521

Control of HIV Through the Inhibition of HIV-1 Integrase: A Medicinal Chemistry Perspective

Volume:3   Issue:2
Pp: 199-220
C. P. Gordon, R. Griffith and P. A. Keller
DOI: 10.2174/157340607780059558