Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Synthesis of Variously Substituted 3-Phenoxymethyl Quinoxalin-2-Ones and Quinoxalines Capable to Potentiate In Vitro the Antiproliferative Activity of Anticancer Drugs in Multi-Drug Resistant Cell Lines

Volume:2   Issue:2
Pp: 113-122
Roberta Loddo, Paolo La Colla, Bernardetta Busonera, Gabriella Collu, Giuseppe Paglietti, Sandra Piras, Antonio Carta and Mario Loriga
DOI: 10.2174/157340606776056197

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New Cysteine Derivatives with Antiproliferative Activity on Melanoma Cells

Volume:2   Issue:2
Pp: 123-132
D. P. Fairlie, P. G. Parsons, A. J. Lucke and G. M. Boyle
DOI: 10.2174/157340606776056124

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Design, Synthesis and Antimalarial Activity of a New Class of Iron Chelators

Volume:2   Issue:2
Pp: 133-138
Kumkum Srivastava, S. B. Katti, Sunil K. Puri, W. Haq and V. R. Solomon
DOI: 10.2174/157340606776056179

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Novel (S)-(-)- and R-(+)-seco-iso-cyclopropylfurano[e]indoline-5,6,7- trimethoxyindole-2-carboxamide (iso-CFI) Analogs of Duocarmycin C2: Synthesis and Biological Evaluation

Volume:2   Issue:2
Pp: 139-146
John A. Hartley, Moses Lee, Konstantinos Kiakos, Stephen Hudson, Heather Townes, Kaitlin Summerville, Adrienne Scott, Brian Lingerfelt and Bethany Purnell
DOI: 10.2174/157340606776056188

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Curcumin is an Inhibitor of p300 Histone Acetylatransferase

Volume:2   Issue:2
Pp: 169-174
Len Neckers, Jane Trepel, Sunmin Lee, Eun-Joo Chung, Min-Jung Lee, Yun-Jin Jung and Monica G. Marcu
DOI: 10.2174/157340606776056133

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Drug Evolution Concept in Drug Design: 2. Chimera Method

Volume:2   Issue:2
Pp: 175-189
G. Roman, T. Popek, C. Lazar, T. Kiyota, A. Kluczyk and Y. Konishi
DOI: 10.2174/157340606776056214

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FAMS Complex: A Fully Automated Homology Modeling System for Protein Complex Structures

Volume:2   Issue:2
Pp: 191-201
Mayuko Takeda-Shitaka, Genki Terashi, Chieko Chiba, Daisuke Takaya and Hideaki Umeyama
DOI: 10.2174/157340606776056160

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Mitogen Activated Protein (MAP) Kinases: Development of ATP and Non- ATP Dependent Inhibitors

Volume:2   Issue:2
Pp: 213-222
Chad N. Hancock, Alba T. Macias, Alexander D. MacKerell, Jr. and Paul Shapiro
DOI: 10.2174/157340606776056151

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