Medicinal Chemistry


Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki


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The Modulation of Inter-Organelle Cross-Talk to Control Apoptosis open Access plus

Volume:2   Issue:1
Pp: 1-12
Morgane L. Bras, Isabelle Rouy and Catherine Brenner
DOI: 10.2174/157340606775197787

Development of Gene Therapies for Cardiovascular and Renal Diseases by Nucleic Acid Medicines open Access plus

Volume:2   Issue:1
Pp: 13-19
Noboru Fukuda
DOI: 10.2174/157340606775197723

Simultaneous Hydrogenolysis of p-Nitrobenzyl Esters and Carbamates Side-Chains in the THF 1β-Carbapenem OCA-983 in Biphasic Media open Access plus

Volume:2   Issue:1
Pp: 21-25
Zhong Li, David How, Phaik-Eng Sum, Yang-I Lin and Tarek S. Mansour
DOI: 10.2174/157340606775197741

New Cathepsin D Inhibitorswith Hydroxyethylamine Isosteres: Preparation and Characterization open Access plus

Volume:2   Issue:1
Pp: 27-38
S. E. Hatfield, W. E. Godwin, K. Sayyar, J. F. Lindley, A. W. Green, C. J. Trana, M. S. McConnell and R. M. McConnell
DOI: 10.2174/157340606775197705

Thienocinnolinone Alkanoic Acid Derivatives as Aldose Reductase Inhibitors open Access plus

Volume:2   Issue:1
Pp: 39-45
G. A. Pinna, D. Rakowitz, L. Costantino, G. E. Grella, G. Boatto, G. Murineddu, B. Asproni and A. Pau
DOI: 10.2174/157340606775197769

Poly(ADP-ribose) Polymerase-1 Inhibitor 3-Aminobenzamide Enhances Apoptosis Induction by Platinum Complexes in Cisplatin-Resistant Tumor Cells open Access plus

Volume:2   Issue:1
Pp: 47-53
Jose M. Perez, Manuel Soto, Celia Quevedo, Carlos Alonso, Victoria Cepeda, Miguel A. Fuertes and Paul A. Nguewa
DOI: 10.2174/157340606775197697

Synthesis and Structure-Activity Relationship on Anticonvulsant Aryl Semicarbazones open Access plus

Volume:2   Issue:1
Pp: 55-62
D. Sriram, J. P. Stables, R. Thirumurugan, S. Induja, J. V. Ragavendran and P. Yogeeswari
DOI: 10.2174/157340606775197778

Sensitization of Multidrug Resistant (MDR) Cancer Cells to Vinblastine by Novel Acridones: Correlation between Anti-Calmodulin Activity and Anti- MDR Activity open Access plus

Volume:2   Issue:1
Pp: 63-77
Y. C. Mayur, T. Padma, B. H. Parimala, K. H. Chandramouli, S. Jagadeesh, N.M. M. Gowda and K. N. Thimmaiah
DOI: 10.2174/157340606775197732

Anti-Proliferative Effects of Novel Glyco-Lipid-Arsenicals (III) on MCF-7 Human Breast Cancer Cells open Access plus

Volume:2   Issue:1
Pp: 79-87
Norbert Wimmer, Jodie A. Robinson, Nagaraj Gopisetty-Venkata, Sarah J. Roberts-Thomson, Gregory R. Monteith and Istvan Toth
DOI: 10.2174/157340606775197714

Current Status of Virtual Screening as Analysed by Target Class open Access plus

Volume:2   Issue:1
Pp: 89-112
Martin J. Stoermer
DOI: 10.2174/157340606775197750