Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Volume:16   Issue: 1
Pp: 1-1
Dimitra Hadjipavlou-Litina
DOI: 10.2174/157340641601191209150546



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Volume:16   Issue: 1
Pp: 2-3
Dimitra Hadjipavlou-Litina
DOI: 10.2174/157340641601191209150949



Thiazole Compounds as Antiviral Agents: An Update

Volume:16   Issue: 1
Pp: 4-23
Inder P. Singh*, Shiv Gupta and Sanjay Kumar
DOI: 10.2174/1573406415666190614101253



Synthesis of New Cyclic Imides Derived From Safrole, Structure- and Ligand-based Approaches to Evaluate Potential New Multitarget Agents Against Species of Leishmania

Volume:16   Issue: 1
Pp: 39-51
José A. de Sousa Luis*, Normando A. da Silva Costa, Cristiane C.S. Luis, Bruno F. Lira, Petrônio F. Athayde-Filho, Tatjana K. de Souza Lima, Juliana da Câmara Rocha, Luciana Scotti and Marcus T. Scotti*
DOI: 10.2174/1573406415666190430144950



The Effects of Trifluoromethylated Derivatives on Prostaglandin E2 and Thromboxane A2 Production in Human Leukemic U937 Macrophages

Volume:16   Issue: 1
Pp: 63-68
Ivana Beara*, Tatjana Majkić, Stefania Fioravanti, Laura Trulli, Neda Mimica-Dukić, Lucio Pellacani and Luciano Saso
DOI: 10.2174/1573406415666190208150253



Evaluation of Cytotoxic Potentials of Some Isoindole-1, 3-Dione Derivatives on HeLa, C6 and A549 Cancer Cell Lines

Volume:16   Issue: 1
Pp: 69-77
Ayse Tan, Ayse Sahin Yaglioglu, Nurhan Horasan Kishali*, Ertan Sahin and Yunus Kara*
DOI: 10.2174/1573406415666181206115638



Synthesis, Anticancer Evaluation and Synergistic Effects with cisplatin of Novel Palladium Complexes: DNA, BSA Interactions and Molecular Docking Study

Volume:16   Issue: 1
Pp: 78-92
Nenad Joksimović, Nenad Janković, Jelena Petronijević, Dejan Baskić, Suzana Popovic, Danijela Todorović, Milan Zarić, Olivera Klisurić, Milan Vraneš, Aleksandar Tot and Zorica Bugarčić*
DOI: 10.2174/1573406415666190128095732



Benzoylthioureas: Design, Synthesis and Antimycobacterial Evaluation

Volume:16   Issue: 1
Pp: 93-103
Tiago O. Brito, Lethícia O. Abreu, Karen M. Gomes, Maria C.S. Lourenço, Patricia M.L. Pereira, Sueli F. Yamada-Ogatta, Ângelo de Fátima, Cesar A. Tisher, Fernando Macedo Jr and Marcelle L.F. Bispo*
DOI: 10.2174/1573406415666181208110753



Design and Synthesis of Novel Sulfonamide-Derived Triazoles and Bioactivity Exploration

Volume:16   Issue: 1
Pp: 104-118
Shi-Chao He, Hui-Zhen Zhang*, Hai-Juan Zhang, Qing Sun and Cheng-He Zhou*
DOI: 10.2174/1573406414666181106124852



Synthesis and Biological Evaluation of 5-benzyl-3-pyridyl-1H-1,2,4-triazole Derivatives as Xanthine Oxidase Inhibitors

Volume:16   Issue: 1
Pp: 119-127
Song-Ye Li , Ting-Jian Zhang , Qing-Xia Wu, Kamara M. Olounfeh, Yi Zhang and Fan-Hao Meng*
DOI: 10.2174/1573406415666190409112209



The Substantial Improvement of Amphotericin B Selective Toxicity Upon Modification of Mycosamine with Bulky Substituents

Volume:16   Issue: 1
Pp: 128-139
Edward Borowski, Natalia Salewska, Joanna Boros-Majewska, Marcin Serocki, Izabela Chabowska, Maria J. Milewska, Dominik Ziętkowski and Sławomir Milewski*
DOI: 10.2174/1573406415666181203114629