Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Volume:14   Issue: 4
Pp: 321-321
Wolf-Rainer Abraham
DOI: 10.2174/157340641404180514151754



The Synthesis of Chalcones as Anticancer Prodrugs and their Bioactivation in CYP1 Expressing Breast Cancer Cells

Volume:14   Issue: 4
Pp: 322-332
Ketan C. Ruparelia*, Keti Zeka, Taeeba Ijaz, Dyan N. Ankrett, Nicola E. Wilsher, Paul C. Butler, Hoon L. Tan, Sabahat Lodhi, Avninder S. Bhambra, Gerard A. Potter, Randolph R.J. Arroo and Kenneth J.M. Beresford
DOI: 10.2174/1573406414666180112120134



Synthesis and in vitro Antioxidant Activity Study of Some Novel Substituted Piperazinyl Flavone Compounds

Volume:14   Issue: 4
Pp: 372-386
Elmas Sari, Pawel Berczynski, Aleksandra Kladna, Irena Kruk, Oya Bozdag Dundar, Monika Szymanska and Hassan Y. Aboul-Enein*
DOI: 10.2174/1573406414666171204105000



A Novel Method to Synthesize Phosphocreatine and Phosphocreatine Prodrugs

Volume:14   Issue: 4
Pp: 387-393
Maria Arkel, Patrizia Garbati, Annalisa Salis, Gianluca Damonte, Nara Liessi, Enrico Adriano, Umberto Benatti, Maurizio Balestrino and Enrico Millo*
DOI: 10.2174/1573406413666171120164702



Activity of Rifabutin and Hemi-synthetic Derivatives Against Mycobacterium abscessus

Volume:14   Issue: 4
Pp: 394-399
Ivy B. Ramis*, Ricardo Figueiredo, Daniela F. Ramos, Priscila C.B. Halicki, Andrea von Groll, Miguel Viveiros, Maria do Ceu Costa and Pedro E.A. da Silva
DOI: 10.2174/1573406414666171204102633



Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents

Volume:14   Issue: 4
Pp: 409-426
Ankit Seth, Piyoosh A. Sharma, Avanish Tripathi, Priyanka K. Choubey, Pavan Srivastava, Prabhash N. Tripathi and Sushant K. Shrivastava*
DOI: 10.2174/1573406414666180116104225