Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Molecular Modeling, de novo Design and Synthesis of a Novel, Extracellular Binding Fibroblast Growth Factor Receptor 2 Inhibitor Alofanib (RPT835)

Volume:12   Issue:4
Pp: 303-317
Ilya Tsimafeyeu, Frits Daeyaert, Jean-Baptiste Joos, Koen V. Aken, John Ludes-Meyers, Mikhail Byakhov and Sergei Tjulandin
DOI: 10.2174/1573406412666160106154726

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Discovery and Optimization of 1-(4-chloro-3-(trifluoromethyl)- phenyl)-3-(2-(amino)pyridin-3-yl)ureas as Novel KDR Kinase Inhibitors

Volume:12   Issue:4
Pp: 328-337
Yu Jiao, Fei Huang, Pengfei Xu, Yanmin Zhang, Shangyan Yang, Danfeng Zhang, Tao Lu and Weifang Tang
DOI: 10.2174/1573406412666151215105149

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Identification of New Inhibitors for Human SIRT1: An in-silico Approach

Volume:12   Issue:4
Pp: 347-361
Balasundaram Padmanabhan, Manjula Ramu, Shruti Mathur, Sruthi Unni and Saravanamuthu Thiyagarajan
DOI: 10.2174/1573406412666160107111612

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Synthesis, Molecular Docking Study, and Cytotoxic Activity of 3,4-diaryl-5-(4-pyridinyl)-1,2,4-oxadiazole

Volume:12   Issue:4
Pp: 394-401
Bita Zareian, Sajad Ghadbeighi, Amirali Amirhamzeh, Seyed N. Ostad, Abbas Shafiee and Mohsen Amini
DOI: 10.2174/1573406412666151112125149

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