Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Assessment In Vitro of a Novel Therapeutic Strategy for Glioma, Combining Herpes Simplex Virus HSV1716-mediated Oncolysis with Gene Transfer and Targeted Radiotherapy

Volume:1   Issue:5
Pp: 423-429
M. Quigg, R. J. Mairs, S. M. Brown, J. Harland, P. Dunn, R. Rampling, A. Livingstone, L. Wilson and M. Boyd
DOI: 10.2174/1573406054864124

Interaction Field Based and Hologram Based QSAR Analysis of Propafenone-type Modulators of Multidrug Resistance

Volume:1   Issue:5
Pp: 431-444
D. Kaiser, M. Smiesko, S. Kopp, P. Chiba and G. F. Ecker
DOI: 10.2174/1573406054864061

Comparison of (+)- and (-)-Hemipalmitoylcarnitinium as Inhibitors of Hepatic Mitochondrial Carnitine Palmitoyltransferases in Diabetic Rats

Volume:1   Issue:5
Pp: 445-453
P. S. Savle, N. E. Neptune, Y. Yang, J. H. Rouden, B. L. Kite, E. W. Sugandhi, R. V. Macri, K. Kashfi and R. D. Gandour
DOI: 10.2174/1573406054864115

Free Energy Perturbation Calculations on Glucosidase-Inhibitor Complexes

Volume:1   Issue:5
Pp: 455-460
F. M. Ruiz and J. R. Grigera
DOI: 10.2174/1573406054864151

Statin Attenuates High Glucose-Induced and Angiotensin II-Induced MAP Kinase Activity Through Inhibition of NAD(P)H Oxidase Activity in Cultured Mesangial Cells

Volume:1   Issue:5
Pp: 461-468
H. Y. Yu, T. Inoguchi, M. Nakayama, H. Tsubouchi, N. Sato, N. Sonoda, S. Sasaki, K. Kobayashi and H. Nawata
DOI: 10.2174/1573406054864052

ICG-001, A Novel Small Molecule Regulator of TCF/β-Catenin Masakatsu Transcription

Volume:1   Issue:5
Pp: 467-472
M. Eguchi, C. Nguyen, S. C. Lee and M. Kahn
DOI: 10.2174/1573406054864098

Enantioselective Synthesis and Preliminary Pharmacological Evaluation of the Enantiomers of Unifiram (DM232), a Potent Cognition-Enhancing Agent

Volume:1   Issue:5
Pp: 473-480
E. Martini, C. Ghelardini, C. Bertucci, S. Dei, F. Gualtieri, L. Guandalini, D. Manetti, S. Scapecchi, E. Teodori and M. N. Romanelli
DOI: 10.2174/1573406054864142

New Features in Synthesis of Talampanel Related 2,3-Benzodiazepines

Volume:1   Issue:5
Pp: 481-485
S. Solyom, I. Pallagi, G. Abraham, M. Kertesz, G. Horvath and P. Berzsenyi
DOI: 10.2174/1573406054864133

3D Solution Structure of [Tyr3]Octreotate Derivatives in DMSO: Structure Differentiation of Peptide Core Due to Chelate Group Attachment and Biologically Active Conformation

Volume:1   Issue:5
Pp: 487-499
G. A. Spyroulias, A. S. Galanis, Ch. Petrou, D. Vahliotis, P. Sotiriou, A. Nikolopoulou, B. Nock, T. Maina and P. Cordopatis
DOI: 10.2174/1573406054864089

N-Terminal Anthranoyl-Phenylalanine Derivatives as CCK1 Receptor Antagonists: The Final Approach

Volume:1   Issue:5
Pp: 501-517
A. Varnavas, L. Lassiani, V. Valenta, A. Ciogli, F. Gasparrini, L. Mennuni and F. Makovec
DOI: 10.2174/1573406054864070