Medicinal Chemistry

Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

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Volume 16 - Issue 4



Matrine-Family Alkaloids: Versatile Precursors for Bioactive Modifications

Volume: 16   Issue: 4
Pp: 431-453
Xiao-hua Cai*, Hong-yan Zhang and Bing Xie*
DOI: 10.2174/1573406415666190507121744



Recent Advances in Therapeutic Applications of Bisbenzimidazoles

Volume: 16   Issue: 4
Pp: 454-486
Smita Verma , Vishnuvardh Ravichandiran, Nihar Ranjan and Swaran J.S. Flora*
DOI: 10.2174/1573406415666190416120801



Synthesis and Antitrypanosomal Profile of Novel Hydrazonoyl Derivatives

Volume: 16   Issue: 4
Pp: 487-494
Natália N. Santiago, Giulianna P. de Alcântara, Juliana S. da Costa, Samir A. Carvalho, Juliana M.C. Barbosa, Kelly Salomão, Solange L. de Castro, Henrique M.G. Pereira and Edson F. da Silva*
DOI: 10.2174/1573406415666190712115237



Synthesis of Silver Nanoparticles using Euphorbia wallichii Extract and Assessment of their Bio-functionalities

Volume: 16   Issue: 4
Pp: 495-506
Abdul-Rehman Phull*, Attarad Ali, Akhtar Ali, Sanaullah Abbasi, Muhammad Zia, Muhammad H. Khaskheli, Ihsan ul Haq and Mohammad A. Kamal*
DOI: 10.2174/1573406415666191111143213



Novel Furan Coupled Quinoline Diamide Hybrid Scaffolds as Potent Antitubercular Agents: Design, Synthesis and Molecular Modelling

Volume: 16   Issue: 4
Pp: 507-516
Anantacharya Rajpurohit, Nayak D. Satyanarayan*, Lokesh Pathak, Siva Ayyanar, Chidambaram R. Rishinaradamangalam and Praveen Shoorapani
DOI: 10.2174/1573406415666190904124630



New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation

Volume: 16   Issue: 4
Pp: 517-530
Elisa Magli, Beatrice Severino*, Angela Corvino, Elisa Perissutti, Francesco Frecentese, Irene Saccone, Flavia Giordano, Marián Castro, José Brea, María I. Loza, Vincenzo Santagada, Giuseppe Caliendo and Ferdinando Fiorino
DOI: 10.2174/1573406415666190613153220



Synthesis of Novel 8-Hydroxyquinoline Derivatives through Mannich Reaction and their Biological Evaluation as Potential Immunomodulatory Agents

Volume: 16   Issue: 4
Pp: 531-543
Shaheen Faizi*, Tahira Sarfaraz, Saima Sumbul, Almas Jabeen, Sobia A. Halim, Mohammad A. Mesaik and Zaheer Ul-Haq*
DOI: 10.2174/1573406415666190626121650



Novel Coupled Molecules from Active Structural Motifs of Synthetic and Natural Origin as Immunosuppressants

Volume: 16   Issue: 4
Pp: 544-554
Richa Minhas, Gulshan Bansal and Yogita Bansal*
DOI: 10.2174/1573406415666190409111459



Synthesis of N-Substituted Benzamide Derivatives and their Evaluation as Antitumor Agents

Volume: 16   Issue: 4
Pp: 555-562
Taiping Chen, Hongwu Jiang, Jianjun Zhou, Zicheng Li*, Wencai Huang, Youfu Luo and Yinglan Zhao
DOI: 10.2174/1573406415666190712120611



Design and Biological Evaluation of Novel Imidazolyl Flavonoids as Potent and Selective Protein Tyrosine Phosphatase Inhibitors

Volume: 16   Issue: 4
Pp: 563-574
Rong Y. Han, Yu Ge, Ling Zhang* and Qing M. Wang
DOI: 10.2174/1573406415666190430125547



Antiglycation Activity of Triazole Schiff’s Bases Against Fructosemediated Glycation: In Vitro and In Silico Study

Volume: 16   Issue: 4
Pp: 575-591
Muniza Shaikh, Salman Siddiqui, Humaira Zafar, Uzma Naqeeb, Fakiha Subzwari, Rehan Imad, Khalid M. Khan and Muhammad I. Choudhary*
DOI: 10.2174/1573406415666190212105718