Medicinal Chemistry

Editor-in-Chief:

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

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Most Accessed Articles

Phenolic Imidazole Derivatives with Dual Antioxidant/Antifungal Activity: Synthesis and Structure-Activity Relationship

Volume: 15   Issue: 4
Pp: 341-351
Ana P. Bettencourt, Marián Castro, João P. Silva, Francisco Fernandes, Olga P. Coutinho, Maria J. Sousa, Maria Fernanda Proença* and Filipe M. Areias*
DOI: 10.2174/1573406414666181005143431

Rational Design of Colchicine Derivatives as anti-HIV Agents via QSAR and Molecular Docking

Volume: 15   Issue: 4
Pp: 328-340
Apilak Worachartcheewan*, Napat Songtawee, Suphakit Siriwong, Supaluk Prachayasittikul*, Chanin Nantasenamat and Virapong Prachayasittikul
DOI: 10.2174/1573406414666180924163756

New N,C-Diaryl-1,2,4-triazol-3-ones: Synthesis and Evaluation as Anticancer Agents

Volume: 15   Issue: 4
Pp: 360-372
Dolores Santa María*, Rosa M. Claramunt, José Elguero, Miguel Carda*, Eva Falomir and Celia Martín-Beltrán
DOI: 10.2174/1573406414666180821103604

USP7: Target Validation and Drug Discovery for Cancer Therapy promotion: free to download

Volume: 14   Issue: 1
Pp: 3-18
Jin Zhou*, Jinzheng Wang, Chao Chen, Haoliang Yuan, Xiaoan Wen* and Hongbin Sun*
DOI: 10.2174/1573406413666171020115539

Cystic Fibrosis Revisited – a Review Study

Volume: 13   Issue: 2
Pp: 102-109
Blanka Klimova, Kamil Kuca, Michal Novotny and Petra Maresova
DOI: 10.2174/1573406412666160608113235

Synthesis and Evaluation of Antifungal and Antitrypanosomastid Activities of Symmetrical 1,4-Disubstituted-1,2,3-Bistriazoles Obtained by CuAAC Conditions

Volume: 15   Issue: 4
Pp: 400-408
Mauricio M. Victor*, Ravir R. Farias, Danielle L. da Silva, Paulo H.F. do Carmo, Maria A. de Resende-Stoianoff, Cláudio Viegas, Patrícia F. Espuri and Marcos J. Marques
DOI: 10.2174/1573406414666181024111522

Spirocyclohexadienones as an Uncommon Scaffold for Acetylcholinesterase Inhibitory Activity

Volume: 15   Issue: 4
Pp: 373-382
Ralph C. Gomes, Renata P. Sakata*, Wanda P. Almeida* and Fernando Coelho*
DOI: 10.2174/1573406414666181109114214

Antiproliferative Activity and Characterization of Metabolites of Aspergillus nidulans: An Endophytic Fungus from Nyctanthes arbor-tristis Linn. Against Three Human Cancer Cell Lines

Volume: 15   Issue: 4
Pp: 352-359
Talea Sana, Bina S. Siddiqui*, Saleem Shahzad, Ahsana D. Farooq, Faheema Siddiqui, Samia Sattar and Sabira Begum
DOI: 10.2174/1573406414666180828124252

Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents

Volume: 15   Issue: 4
Pp: 417-429
Dima A. Sabbah*, Ameerah H. Ibrahim, Wamidh H. Talib, Khalid M. Alqaisi, Kamal Sweidan, Sanaa K. Bardaweel, Ghassan A. Sheikha, Haizhen A. Zhong, Eveen Al-Shalabi, Reema A. Khalaf and Mohammad S. Mubarak
DOI: 10.2174/1573406414666180912111846

New Quinazoline-Sulfonylurea Conjugates: Design, Synthesis and Hypoglycemic Activity

Volume: 15   Issue: 6
Pp: 634-647
Sahar M. Abou-Seri, AlShaimaa M. Taha, Mona A. Mohamed* and Nour M. Abdelkader
DOI: 10.2174/1573406415666181208104543