Recent Patents on Anti-Cancer Drug Discovery


Khurshid Zaman  
Bentham Science Publishers


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PARP Inhibitors in Ovarian Cancer

Volume: 13   Issue: 4
Pp: 392-410
Gloria Mittica, Eleonora Ghisoni, Gaia Giannone, Sofia Genta, Massimo Aglietta, Anna Sapino and Giorgio Valabrega*
DOI: 10.2174/1574892813666180305165256

Oral Submucous Fibrosis as an Overhealing Wound: Implications in Malignant Transformation

Volume: 13   Issue: 3
Pp: 272-291
Mohit Sharma, Smitha S. Shetty and Raghu Radhakrishnan*
DOI: 10.2174/1574892813666180227103147

Novel Patents Targeting Interleukin-17A; Implications in Cancer and Inflammation open access plus

Volume: 13   Issue: 2
Pp: 133-144
Juan F. Santibanez* and Suncica Bjelica
DOI: 10.2174/1574892813666180220105958

Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy promotion: free to download

Volume: 13   Issue: 1
Pp: 2-17
Sandra Iurescia*, Daniela Fioretti and Monica Rinaldi*
DOI: 10.2174/1574892812666171030163804

From a Better Understanding of the Mechanisms of Action of Histone Deacetylases Inhibitors to the Progress of the Treatment of Malignant Lymphomas and Plasma Cell Myeloma open access plus

Volume: 12   Issue: 4
Pp: 283-295
Romeo G. Mihaila*
DOI: 10.2174/1574892812666170920110054

Pharmacological Inhibitors of NAD Biosynthesis as Potential An ticancer Agents

Volume: 12   Issue: 3
Pp: 190-207
Stephanie Lucas, Claire Soave, Ghazal Nabil, Zainab Sabry Othman Ahmed, Guohua Chen, Hossny Awad El-Banna, Q. Ping Dou* and Jian Wang*
DOI: 10.2174/1574892812666170619125503

Marine Derived Anticancer Drugs Targeting Microtubule

Volume: 12   Issue: 2
Pp: 102-127
Oindrila De and Biswa P. Chatterji*
DOI: 10.2174/1574892812666170109141003

Docking and QSAR Studies of 1,4-Dihydropyridine Derivatives as Anti- Cancer Agent

Volume: 12   Issue: 2
Pp: 174-185
Shirin Mollazadeh, Jamal Shamsara, Maryam Iman* and Farzin Hadizadeh*
DOI: 10.2174/1574892812666170126162521

Kinase Inhibitor Indole Derivatives as Anticancer Agents: A Patent Review

Volume: 12   Issue: 1
Pp: 55-72
Anuj K. Rathi, Riyaz Syed, Vijay Singh, Han-Seung Shin and Rahul V. Patel
DOI: 10.2174/1574892811666161003112119

Medicinal Chemistry Insights into Novel HDAC Inhibitors: An Updated Patent Review (2012-2016)

Volume: 12   Issue: 1
Pp: 16-34
Peng Zhan, Xueshun Wang, Xinyong Liu and Takayoshi Suzuki
DOI: 10.2174/1574892811666161101102842

Recent Patents on Proteasome Inhibitors of Natural Origin

Volume: 12   Issue: 1
Pp: 4-15
Daniela Correia da Silva, Paula B. Andrade, Vera Ribeiro, Patricia Valentao and David M. Pereira
DOI: 10.2174/1574892812666161123142037

HOXB7 and Hsa-miR-222 as the Potential Therapeutic Candidates for Metastatic Colorectal Cancer

Volume: 11   Issue: 4
Pp: 434-443
Maryam Iman, Seyede Samaneh Mostafavi, Seyed Shahriar Arab, Sadegh Azimzadeh and Mansour Poorebrahim
DOI: 10.2174/1574892811999160628114857

Developing Antitumor Magnetic Hyperthermia: Principles, Materials and Devices

Volume: 11   Issue: 4
Pp: 360-375
Alexander M. Tishin, Alexander A. Shtil, Alexander P. Pyatakov and Vladimir I. Zverev
DOI: 10.2174/0929866523666160720094638

Liposomal Irinotecan in the Treatment of Refractory Pancreatic Cancer

Volume: 11   Issue: 4
Pp: 376-383
Harold Bien, Gerardo G. Mackenzie and Minsig Choi
DOI: 10.2174/1574892811666160729094415

Mapping the Technological Knowledge Landscape: The Case of Epigenetics

Volume: 11   Issue: 4
Pp: 424-433
Chie Hoon Song, Janghyeok Yoon, Namuk Ko and Jeung-Whan Han
DOI: 10.2174/1574892811666160825143006

Causal Therapy of Breast Cancer Irrelevant of Age, Tumor Stage and ER-Status: Stimulation of Estrogen Signaling Coupled With Breast Conserving Surgery* open access plus

Volume: 11   Issue: 3
Pp: 254-266
Zsuzsanna Suba
DOI: 10.2174/1574892811666160415160211

HER3 and its Ligand, Heregulin, as Targets for Cancer Therapy

Volume: 11   Issue: 3
Pp: 267-274
Hisato Kawakami and Kimio Yonesaka
DOI: 10.2174/1574892811666160418123221

Review of PI3K/mTOR Inhibitors Entering Clinical Trials to Treat Triple Negative Breast Cancers

Volume: 11   Issue: 3
Pp: 283-296
Amélie Fouqué, Mickael Jean, Pierre van de Weghe and Patrick Legembre
DOI: 10.2174/1574892811666160519113731

Improved Anti-Tumor Activity of Novel Highly Bioactive Liposome-Bound TRAIL in Breast Cancer Cells

Volume: 11   Issue: 2
Pp: 197-214
Diego De Miguel, Ana Gallego-Lleyda, José M. Ayuso, Aleksandra Pawlak, Blanca Conde, Ignacio Ochoa, Luis J. Fernández, Alberto Anel and Luis Martinez-Lostao
DOI: 10.2174/1574892811666160229121544

Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment open access plus

Volume: 11   Issue: 2
Pp: 184-196
Li Huang, Rongzhang He, Weihao Luo, Yuan-Shan Zhu, Jia Li, Tan Tan, Xi Zhang, Zheng Hu and Dixian Luo
DOI: 10.2174/1574892811888160304113346

Isoliquiritigenin Inhibits Proliferation and Induces Apoptosis via Alleviating Hypoxia and Reducing Glycolysis in Mouse Melanoma B16F10 Cells

Volume: 11   Issue: 2
Pp: 215-227
Yanming Wang, Jun Ma, Xinyan Yan, Xiaoyu Chen, Lingling Si, Ying Liu, Jichun Han, Wenjin Hao and Qiusheng Zheng
DOI: 10.2174/1573406412666160307151904

Trends in Biotechnological Drugs for Cancer Treatment promotion: free to download

Volume: 11   Issue: 1
Pp: 112-120
Natalia L. von Ranke, Iolanda M. Fierro and Adelaide M.S. Antunes
DOI: 10.2174/1574892810666150928160202

Multi-Targeted Agents in Cancer Cell Chemosensitization: What We Learnt from Curcumin Thus Far promotion: free to download

Volume: 11   Issue: 1
Pp: 67-97
Devivasha Bordoloi, Nand K. Roy, Javadi Monisha, Ganesan Padmavathi and Ajaikumar B. Kunnumakkara
DOI: 10.2174/1574892810666151020101706

Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In vivo, In vitro and Network Analyses promotion: free to download

Volume: 11   Issue: 1
Pp: 121-133
Amr Amin, Alaaeldin A. Hamza, Sayel Daoud, Kamal Khazanehdari, Ala’a Al Hrout, Badriya Baig, Amphun Chaiboonchoe, Thomas E. Adrian, Nazar Zaki and Kourosh Salehi-Ashtiani
DOI: 10.2174/1574892810666151102110248

Perspectives in Engineered Mesenchymal Stem/Stromal Cells Based Anti- Cancer Drug Delivery Systems promotion: free to download

Volume: 11   Issue: 1
Pp: 98-111
Darinka Gjorgieva Ackova, Tatjana Kanjevac, Lia Rimondini and Darko Bosnakovski
DOI: 10.2174/1574892811666151111142721

Quinazolines as Apoptosis Inducers and Inhibitors: A Review of Patent Literature promotion: free to download

Volume: 11   Issue: 1
Pp: 2-66
Samir Mehndiratta, Sameer Sapra, Gurpreet singh, Manwinder Singh and Kunal Nepali
DOI: 10.2174/1574892811666151218151506

FOXM1 and its Oncogenic Signaling in Gastric Cancer

Volume: 10   Issue: 3
Pp: 270-279
Hanying Wang and Chen Huang
DOI: 10.2174/1574892810666150617112421

pH Gradient Reversal: An Emerging Hallmark of Cancers

Volume: 10   Issue: 3
Pp: 244-258
Mohit Sharma, Madhusudan Astekar, Sonal Soi, Bhari S. Manjunatha, Devi C. Shetty and Raghu Radhakrishnan
DOI: 10.2174/1574892810666150708110608

Cabozantinib in Thyroid Cancer open access plus

Volume: 10   Issue: 3
Pp: 259-269
Poupak Fallahi, Silvia M. Ferrari, Flavia Di Bari, Gabriele Materazzi, Salvatore Benvenga, Paolo Miccoli and Alessandro Antonelli
DOI: 10.2174/1574892810666150708110816

“Impact of Smoking Cessation Treatment” on Lung Function and Response Rate in EGFR Mutated Patients: A Short-Term Cohort Study

Volume: 10   Issue: 3
Pp: 342-351
Aldo Pezzuto, Luciano Stumbo, Marco Russano, Pierfilippo Crucitti, Simone Scarlata, Marco Caricato and Giuseppe Tonini
DOI: 10.2174/1574892810666150806111014

HDAC Inhibitors as Novel Anti-Cancer Therapeutics

Volume: 10   Issue: 2
Pp: 145-162
Cristabelle De Souza and Biswa P. Chatterji
DOI: 10.2174/1574892810666150317144511

New Perspective Therapy of Breast Cancer Based on Selective Dopamine Receptor D2 Agonist and Antagonist Effects on MCF-7 Cell Line

Volume: 10   Issue: 2
Pp: 214-223
Majid Pornour, Ghasem Ahangari, Seyed H. Hejazi and Abdolkhalegh Deezagi
DOI: 10.2174/1574892810666150416111831

Immune Checkpoint Inhibition: Therapeutic Implications in Epithelial Ovarian Cancer

Volume: 10   Issue: 2
Pp: 133-144
Teresa C. Longoria and Ramez N. Eskander
DOI: 10.2174/1574892810666150504121000

Alteronol Induces Differentiation of Melanoma B16-F0 Cells promotion: free to download

Volume: 10   Issue: 1
Pp: 116-127
Caixia Wang, Bo Zhang, Na Chen, Liangliang Liu, Jinglei Liu, Qi Wang, Zhenhua Wang, Xiling Sun and Qiusheng Zheng
DOI: 10.2174/1574892809666140923125521

Cancer Stem Cells: The ‘Achilles Heel’ of Chemo-Resistant Tumors promotion: free to download

Volume: 10   Issue: 1
Pp: 2-22
In-Sun Hong, Hwa-Yong Lee and Jeong-Seok Nam
DOI: 10.2174/1574892809666141129172658

Targeting Hormonal Signaling Pathways in Castration Resistant Prostate Cancer

Volume: 9   Issue: 3
Pp: 267-285
Marilena Manea, Marina Montagnani Marelli, Roberta M. Moretti, Roberto Maggi, Monica Marzagalli and Patrizia Limonta
DOI: 10.2174/1574892809666140520113953

Cell Surface Nucleolin as a Target for Anti-Cancer Therapies

Volume: 9   Issue: 2
Pp: 137-152
Marina Koutsioumpa and Evangelia Papadimitriou
DOI: 10.2174/1574892808666131119095953