Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Abstract Ahead of Print

Tryptanthrin analogues as inhibitors of enoyl-acyl carrier protein reductase: activity against Mycobacterium tuberculosis, toxicity, modeling of enzyme binding

Volume:19
Gheorghe H Duca, Serghei Pogrebnoi, Veaceslav Boldescu, Fatma Aksakal, Andrei Uncu, Vladimir Valica, Livia Uncu, Simona Negreș, Florica Nicolescu and Fliur Macaev*

Algorithmic and Stochastic Representations of Gene Regulatory Networks and Protein-Protein Interactions

Volume:19
Alexiou Athanasios*, Chatzichronis Stylianos, Asma Perveen, Abdul Hafeez and Ghulam Md Ashraf *

Pharmaceutical Interfering of Neddylation as Promising Treatments for Various Cancers

Volume:19
Lina Yin, Yuanyuan Xue, Qiannan Shang, Haichao Zhu, Meihua Liu, Yingxiang Liu and Qingzhong Hu*

How cancer cells resist chemotherapy: Design and Development of Drugs Targeting

Volume:19
Vadim V. Tarasov Tarasov, Vladimir N. Chubarev, Ghulam Md Ashraf, Samira A. Dostdar, Alexander V. Sokolov, Tatiana I. Melnikova, Susanna S. Sologova, Ekaterina M. Grigorevskich, Alfiya Makhmutovа, Alexander S. Kinzirsky, Sergey G. Klochkov and Gjumrakch Aliev*

In Vitro, In Silico and Ex Vivo Studies of Dihydroartemisinin derivatives as antitubercular agents

Volume:19
Komal Kalani, Sarfraz Alam, Vineeta Chaturvedi, Feroz Khan and Santosh Kumar Srivastava*

4H-1,3-Benzothiazin-4-one a promising class against MDR/XDR-TB

Volume:19
Marcus Vinicius Nora de Souza* and Thais Cristina Mendonça Nogueira

Synthesis, Screening and Docking Analysis of Hispolon Pyrazoles and Isoxazoles as Potential Antitubercular Agents

Volume:19
Neduri V. Balaji, Bollikolla HariBabu*, Vanga Umamaheswara Rao, Gottumukkala V. Subbaraju, Kurre Purna Nagasree and Muthyala Murali Krishna Kumar*

Targeting Kinase Interaction Networks: A New Paradigm In Ppi Based Design Of Kinase Inhibitors

Volume:19
Pranitha Jenardhanan, Manivel Panneerselvam and Premendu P. Mathur*

Applications of in silico Methods for Design and Development of Drugs Targeting Protein-Protein Interactions

Volume:19
Vittoria Cicaloni, Alfonso Trezza, Francesco Pettini and Ottavia Spiga*

Protein/ Hormone Based Nanoparticles as Carriers for Drugs Targeting Protein-Protein Interactions

Volume:19
Ebtesam Al-Suhaimi*, Vijaya Ravinayagam, B. Rabindran Jermy, Tarhini Mohamad and Abdelhamid Elaissari

Influence of Amino Acid Mutations and Small Molecules for Targeted Inhibition of Proteins Involved in Cancer

Volume:19
Vishnupriya Kanakaveti, P. Anoosha, R. Sakthivel, S. K. Rayala and M. Michael Gromiha*

Dihydroartemisinin and its analogs: A new class of antitubercular agents

Volume:19
Komal Kalani, Vineeta Chaturvedi, Sudeep Tondon and Santosh Kumar Srivastava*

Targeting DNA gyrase to combat Mycobacterium tuberculosis: An update

Volume:19
Swetarka Das, Tanu Garg, Nanduri Srinivas, Arunava Dasgupta and Sidharth Chopra*

Synthesis and antibacterial activity of Mefloquine-based analogs against sensitive and resistant Mycobacterium tuberculosis strains

Volume:19
Adriele da Silva Araújo , Adriana Marques Moraes, Maria Cristina S. Lourenço, Cláudia O. Pessoa, Emerson Teixeira da Silva and Marcus Vinícius Nora de Souza*

Acid Ceramidase; A Novel Therapeutic Target in Cancer

Volume:19
Yadu Vijayan, Manendra Babu Lankadasari and Kuzhuvelil B. Harikumar*

An Overview of HDAC Inhibitors and their Synthetic Routes

Volume:19
Xiaopeng Peng, Guochao Liao, Pinghua Sun, Zhiqiang Yu and Jianjun Chen*

Imidazole and 1,2,4-Triazole-based Derivatives Gifted with Antitubercular Activity: Cytotoxicity and Computational Assessment

Volume:19
Daniele Zampieri*, Francesca Cateni, Mariarosa Moneghini, Marina Zacchigna, Erik Laurini, Domenico Marson, Alessandro De Logu, Adriana Sanna and Maria G. Mamolo

An Overview on the Potential Antimycobacterial Agents Targeting Serine/Threonine Protein Kinases from Mycobacterium tuberculosis

Volume:19
Matteo Mori, José Camilla Sammartino, Luca Costantino, Arianna Gelain, Fiorella Meneghetti, Stefania Villa and Laurent Roberto Chiarelli

Peptides as Potential Anticancer Agents

Volume:19
Shams Aaghaz*, Vivek Gohel and Ahmed Kamal*