Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Articles Ahead of Print

The Value of Neuroimaging Techniques in the Translation and Trans- Diagnostic Validation of Psychiatric Diagnoses – Selective Review

Volume:20
Anna Todeva-Radneva*, Rositsa Paunova, Sevdalina Kandilarova and Drozdstoy St. Stoyanov

Natural Products as a Paradigm for the Treatment of Coxsackievirusinduced Myocarditis

Volume:20
Madhu Khanna*, Anju Gautam, Roopali Rajput and Latika Sharma

Recent Development of 1,2,4-triazole-containing Compounds as Anticancer Agents

Volume:20
Xiaoyue Wen, Yongqin Zhou*, Junhao Zeng and Xinyue Liu

Access to a Library of 1,3-disubstituted-1,2,3-triazenes and Evaluation of their Antimicrobial Properties

Volume:20
Insa Seck, Samba Fama Ndoye, Lalla Aicha Ba, Alioune Fall, Abdoulaye Diop, Ismaïla Ciss, Abda Ba, Cheikh Sall, Amadou Diop, Cheikh Sadibou Boye, Generosa Gomez, Yagamare Fall and Matar Seck*

In Vitro α-glucosidase Inhibition and Computational Studies of Kaempferol Derivatives from Dryopteris cycanida

Volume:20
Surriya Amin, Barkat Ullah, Mumtaz Ali, Haroon Khan*, Abdur Rauf, Sher Ali Khan and Eduardo Sobarzo-Sánchez*

Moxifloxacin-isatin Hybrids Tethered by 1,2,3-triazole and their Anticancer Activities

Volume:20
Mingli Yang, Hailin Liu*, Yazhou Zhang*, Xiujun Wang* and Zhi Xu

An Update on Glutamatergic System in Suicidal Depression and on the role of Esketamine

Volume:20
Domenico De Berardis*, Carmine Tomasetti, Maurizio Pompili, Gianluca Serafini, Federica Vellante, Michele Fornaro, Alessandro Valchera, Giampaolo Perna, Umberto Volpe, Giovanni Martinotti, Silvia Fraticelli, Massimo Di Giannantonio, Yong-Ku Kim and Laura Orsolini

Periodontal Pathogens and Neuropsychiatric Health

Volume:20
Abhishek Wadhawan, Mark A. Reynolds, Hina Makkar, Alison J. Scott, Eileen Potocki, Andrew J. Hoisington, Lisa A. Brenner, Aline Dagdag, Christopher A. Lowry, Yogesh Dwivedi and Teodor T. Postolache*

Clinical Relevance of Alternative Lengthening of Telomeres in Cancer

Volume:20
Guilherme G. da Silva, Karollyne S. Morais, Daniel S. Arcanjo and Diêgo M. de Oliveira*

Potential Telomere-Related Pharmacological Targets

Volume:20
Joseph Berei, Adam Eckburg, Edward Miliavski, Austin D. Anderson, Rachel J. Miller, Joshua Dein, Allison M. Giuffre, Diana Tang, Shreya Deb, Kavya Sri Racherla, Meet Patel, Monica Saravana Vela and Neelu Puri*

Targeting Tau Hyperphosphorylation via Kinase Inhibition: Strategy to Address Alzheimer's Disease

Volume:20
Ahmad Abu TurabNaqvi, Gulam Mustafa Hasan and Md. Imtaiyaz Hassan*

Telomere- Related Markers for Cancer

Volume:20
Xiaotian Yuan, Mingkai Dai and Dawei Xu*

Withdrawal Notice: Updated Understanding of the Degenerative Disc Diseases - Causes Versus Effects - Treatments, Studies and Hypothesis

Volume:19
Cristian Muresanu, Siva G. Somasundaram, Margarita E. Neganova, Elena V. Bovina, Sergey V. Vissarionov, Okom N. F. C. Ofodile, Vladimir P. Fisenko, Valentin Bragin, Nina N. Minyaeva, Vladimir N. Chubarev, Sergey G. Klochkov, Vadim V. Tarasov, Cecil E. Kirkland and Gjumrakch Aliev*

Withdrawal Notice: A Chlorhexidine-containing Brush-on Gel as Adjuvant Treatment for Plaque-Induced Gingivitis

Volume:19
Gianna Maria Nardi , Roberta Grassi, Guglielmo Campus, Maria Letizia Pareti , Dario Di Stasio and Fedora della Vella*

Withdrawal Notice: The Long-Term Effect of Medically Enhancing Melanin Intrinsic Bioenergetics Capacity in Prematurity

Volume:19
Arturo Solís Herrera, Paola E. Solís Arias, María del Carmen Arias Esparza, Luis Fernando Torres Bernal, Andrey D. Bondarev, Vladimir P. Fisenko, Vladimir N. Chubarev, Nina N. Minyaeva, Lyudmila M. Mikhaleva, Vadim V. Tarasov, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*

Withdrawal Notice: The Association of Sleep Disorders, Obesity, and Sleep-Related Hypoxia with Cancer

Volume:19
Anna Brzecka, Karolina Sarul, Tomasz Dyła, Marco Avila-Rodriguez, Ricardo Cabezas-Perez, Vladimir N. Chubarev, Nina N. Minyaeva, Sergey G. Klochkov, Margarita E. Neganova, Liudmila M. Mikhaleva, Siva G. Somasundaram, Cecil E. Kirkland, Vadim V. Tarasov and Gjumrakch Aliev*

Inhibition of Hemoglobin Degrading Protease Falcipain-2 as a Mechanism for Anti-Malarial Activity of Triazole-Amino Acid Hybrids

Volume:20
Vigyasa Singh, Rahul Singh Hada, Amaduddin, Babita Aneja, Mohammad Abid, Kailash C. Pande and Shailja Singh*

Focusing on DNA Repair and Damage Tolerance Mechanisms in Mycobacterium tuberculosis: An Emerging Therapeutic Theme

Volume:20
Pooja Mittal, Rajesh Sinha, Amit Kumar, Pooja Singh, Archana Singh, Moses Rinchui Ngasainao and Indrakant K. Singh*

Outwitting an Old Neglected Nemesis: A Review on Leveraging Integrated Data-Driven Approaches to Aid in Unraveling of Leishmanicides of Therapeutic Potential

Volume:20
Samuel K. Kwofie*, Emmanuel Broni, Bismark Dankwa, Kweku S. Enninful, Gabriel B. Kwarko, Louis Darko, Ravi Durvasula, Prakasha Kempaiah, Brijesh Rathi, Whelton A. Miller III, Abu Yaya and Michael D. Wilson

PEGylation and Cell-Penetrating Peptides: Glimpse into the Past and Prospects in the Future

Volume:20
Sumit Kumar, Devender Singh, Pooja Kumari, Rajender Singh Malik, Poonam, Keykavous Parang and Rakesh Kumar Tiwari*

Mathematical Modeling to Address Challenges in Pancreatic Cancer

Volume:20
Prashant Dogra, Javier Ruiz Ramírez, María J. Peláez, Zhihui Wang, Vittorio Cristini, Gulshan Parasher and Manmeet Rawat*

4-Oxoquinoline Derivatives as Antivirals: A Ten Years Overview

Volume:20
Pedro N. Batalha, Luana da S. M. Forezi, Nathalia M. de C. Tolentino, Fernanda S. Sagrillo, Vanessa G. de Oliveira, Maria Cecília B. V. de Souza and Fernanda da C. S. Boechat*

A Novel Hydrocolloid Film Based on Pectin, Starch and Gunnera tinctoria and Ugni molinae Plant Extracts for Wound Dressing Applications

Volume:20
Constanza Sabando, Walther Ide, Maité Rodríguez-Díaz, Gustavo Cabrera-Barjas, Johanna Castaño, Rebeca Bouza, Niels Müller, Cristian Gutiérrez, Luis Barral, Joaquín Rojas, Fernando Martínez and Saddys Rodríguez-Llamazares*

Synthesis, In Vitro and In Silico Studies of Indolequinone Derivatives against Clinically Relevant Bacterial Pathogens

Volume:20
Talita Odriane Custodio Leite, Juliana Silva Novais, Beatriz Lima Cosenza de Carvalho, Vitor Francisco Ferreira, Leonardo Alves Miceli, Letícia Fraga, Bárbara Abrahim-Vieira, Carlos Rangel Rodrigues, Agnes Marie Sá Figueiredo, Helena Carla Castro and Anna Claudia Cunha*

Phenylamino-pyrimidine (PAP) Privileged Structure: Synthesis and Medicinal Applications

Volume:20
Luiz Claudio Ferreira Pimentel , Anna Claudia Cunha , Lucas Villas Boas Hoelz, Henayle Fernandes Canzian , Debora Inacio Leite Firmino Marinho, Nubia Boechat and Monica Macedo Bastos*

Integrated Protocol to Design Potential Inhibitors of Dipeptidyl Peptidase- 4 (DPP-4)

Volume:20
Simone Queiroz Pantaleão, Eric Allison Philot, Michell de Oliveira Almeida, Angelica Nakagawa Lima, Mirela Inês de Sairre, Ana Ligia Scott and Kathia Maria Honorio*

Antioxidant and Antibacterial Activity of Sulfonamides Derived from Carvacrol: A Structure-Activity Relationship Study

Volume:19
Aldo S. de Oliveira*, Luiz F. S. de Souza, Ricardo J. Nunes, Susana Johann, David L. Palomino-Salcedo, Leonardo L. G. Ferreira and Adriano D. Andricopulo

Isoform-Selective PI3K Inhibitors for Various Diseases

Volume:20
Rammohan R. Yadav Bheemanaboina*

Molecular Docking and Quantum Studies of Lawsone Dimers Derivatives: New Investigation of Antioxidant Behavior and Antifungal Activity

Volume:20
Aldo S. de Oliveira*, David L. Palomino-Salcedo, Eduardo Zapp, Daniela Brondani, Thaynara D. Hoppe, Patrícia B. Brondani, Lidiane Meier, Susana Johann, Leonardo L. G. Ferreira and Adriano D. Andricopulo

In Silico Studies for Bacterystic Evaluation against Staphylococcus aureus of 2-naftomic Acid Analogues

Volume:19
Alex France Messias Monteiro, Marcus Tullius Scotti *, Alejandro Speck-Planche, Renata Priscila Costa Barros and Luciana Scotti

MCDCalc: Markov Chain Molecular Descriptors Calculator for Medicinal Chemistry

Volume:20
Paula Carracedo-Reboredo, Ramiro Corona, Mikel Martinez-Nunes, Carlos Fernandez-Lozano, Georgia Tsiliki, Haralambos Sarimveis, Eider Aranzamendi, Sonia Arrasate, Nuria Sotomayor, Esther Lete, Cristian Robert Munteanu and Humbert González-Díaz *

Antibacterial Activity of Cissus incisa Extracts against Multidrug- Resistant Bacteria

Volume:19
Deyani Nocedo-Mena, Elvira Garza-González, Mauricio González-Ferrara and María del Rayo Camacho-Corona*

Machine Learning as a Proposal for a Better Application of Food Nanotechnology Regulation in the European Union

Volume:19
Ricardo Santana *, Enrique Onieva, Robin Zuluaga, Aliuska Duardo-Sánchez and Piedad Gañán

Telomerase-based Cancer Therapeutics: A Review on their Clinical Trials

Volume:20
Nicola Relitti*, A Prasanth Saraswati, Stefano Federico, Tuhina Khan, Margherita Brindisi, Daniela Zisterer, Simone Brogi, Sandra Gemma, Stefania Butini and Giuseppe Campiani

Kynurenine Metabolism During Depressive, Manic, and Euthymic Phases of Bipolar Affective Disorder

Volume:19
Alexander Maget, Martina Platzer*, Susanne A. Bengesser, Frederike T. Fellendorf, Armin Birner, Robert Queissner, Carlo Hamm, Bernd Reininghaus, Andrzej Hecker, Lukas Tomberger, Renè Pilz, Nina Dalkner, Natalie Moll, Gregor Schütze, Markus Schwarz, Hans P. Kapfhammer and Eva Z. Reininghaus