Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Editorial [Hot topic: Medicinal Chemistry in the Pilot Phase of the Molecular Libraries Screening Center Network (Guest Editor: Donna M. Huryn)] promotion: free to download

Volume:9   Issue: 13
Pp: 1158-1158
Donna M. Huryn
DOI: 10.2174/156802609789753626

Cancer and Virus Leads by HTS, Chemical Design and SEA Data Mining

Volume:9   Issue: 13
Pp: 1159-1171
Pahk Thepchatri, Jaeki Min, Thota Ganesh, Yuhong Du, Iestyn Lewis, Serdar Kurtkaya, Andrew Prussia, Lian Li, Blossom Sneed, Richard K. Plemper, Haian Fu, Dennis C. Liotta, James P. Snyder, Raymond Dingledine and Aiming Sun
DOI: 10.2174/156802609789753581

Small-Molecule Modulators of the NF-κB Pathway Newly Identified by a Translocation-Based Cellular Assay

Volume:9   Issue: 13
Pp: 1172-1180
Yuli Xie, Alison Rinderspacher, Yidong Liu, Gangli Gong, Deborah H. Smith, Michael Wyler, Lars Branden and Shi-Xian Deng
DOI: 10.2174/156802609789753617

The Pilot Phase of the NIH Chemical Genomics Center

Volume:9   Issue: 13
Pp: 1181-1193
Craig J. Thomas, Douglas S. Auld, Ruili Huang, Wenwei Huang, Ajit Jadhav, Ronald L. Johnson, William Leister, David J. Maloney, Juan J. Marugan, Sam Michael, Anton Simeonov, Noel Southall, Menghang Xia, Wei Zheng, James Inglese and Christopher P. Austin
DOI: 10.2174/156802609789753644

A Case Study from the Chemistry Core of the Pittsburgh Molecular Library Screening Center: The Polo-like Kinase Polo-Box Domain (Plk1- PBD)

Volume:9   Issue: 13
Pp: 1194-1205
Peter Wipf, David Arnold, Karen Carter, Shuzhi Dong, Paul A. Johnston, Elizabeth Sharlow, John S. Lazo and Donna H. Huryn
DOI: 10.2174/156802609789753590

Discovery and Development of a Potent and Highly Selective Small Molecule Muscarinic Acetylcholine Receptor Subtype I (mAChR 1 or M1) Antagonist In Vitro and In Vivo Probe

Volume:9   Issue: 13
Pp: 1217-1226
C. David Weaver, Douglas J. Sheffler, L. Michelle Lewis, Thomas M. Bridges, Richard Williams, Natalia T. Nalywajko, J. Phillip Kennedy, Matthew M. Mulder, Satyawan Jadhav, Leslie A. Aldrich, Carrie K. Jones, Joy Marlo, Colleen M. Niswender, Matthew M. Mock, Fang Zheng, P. Jeffrey Conn and Craig W. Lindsley
DOI: 10.2174/156802609789753635

Discovery of Selective Probes and Antagonists for G Protein-Coupled Receptors FPR/FPRL1 and GPR30

Volume:9   Issue: 13
Pp: 1227-1236
Jeffrey B. Arterburn, Tudor I. Oprea, Eric R. Prossnitz, Bruce S. Edwards and Larry A. Sklar
DOI: 10.2174/156802609789753608