Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Editorial [Hot topic: Medicinal Chemistry Strategies to Minimize hERG Channel Effects 23 May (Guest Editor:Mark T. Bilodeau)] promotion: free to download

Volume:8   Issue: 13
Pp: 1101-1101
Mark T. Bilodeau
DOI: 10.2174/156802608785700025

The hERG Channel and Risk of Drug-Acquired Cardiac Arrhythmia: An Overview

Volume:8   Issue: 13
Pp: 1102-1112
Armando A. Lagrutta, Elena S. Trepakova and Joseph J. Salata
DOI: 10.2174/156802608785700016

Ligand Structural Aspects of hERG Channel Blockade

Volume:8   Issue: 13
Pp: 1113-1127
Alex M. Aronov
DOI: 10.2174/156802608785700061

The Impact of IKr Blockade on Medicinal Chemistry Programs

Volume:8   Issue: 13
Pp: 1128-1139
Ian M. Bell and Mark T. Bilodeau
DOI: 10.2174/156802608785700034

Overcoming hERG Affinity in the Discovery of Maraviroc; A CCR5 Antagonist for the Treatment of HIV

Volume:8   Issue: 13
Pp: 1140-1151
David A. Price, Duncan Armour, Marcel de Groot, Derek Leishman, Carolyn Napier, Manos Perros, Blanda L. Stammen and Anthony Wood
DOI: 10.2174/156802608785700007

Lead Optimization of Melanin Concentrating Hormone Receptor 1 Antagonists with low hERG Channel Activity

Volume:8   Issue: 13
Pp: 1152-1157
Andrew S. Judd, Andrew J. Souers and Philip R. Kym
DOI: 10.2174/156802608785700052

Molecule of the Month

Volume:8   Issue: 13
Pp: 1158-1158
Craig W. Lindsley
DOI: 10.2174/156802608785700043