Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Editorial (Thematic Issue: Heterocycle and Hydrocarbon Compounds from Natural Sources in Medicinal Chemistry: From Synthesis to Computational Design in Pharmacological Applications – Part II) free to download

Volume:17   Issue: 4
Pp: 381-382
Eduardo Sobarzo-Sanchez
DOI: 10.2174/1568026616666160906142336



Mechanisms Underlying Anti-hyperalgesic Properties of Kaempferol-3,7- di-O-α-L-rhamnopyranoside Isolated from Dryopteris cycadina

Volume:17   Issue: 4
Pp: 383-390
Mumtaz Ali, Abdur Rauf, Taibi Ben Hadda, Saud Bawazeer, Tareq Abu-Izneid, Haroon Khan, Muslim Raza, Sher Ali Khan, S. U.A. Shah, Samreen Pervez, Seema Patel and Ilkay Erdogan Orhan
DOI: 10.2174/1568026616666160824101429



Coumarin and Derivates as Lipid Lowering Agents

Volume:17   Issue: 4
Pp: 391-398
Silvia Tejada, Miquel Martorell, Xavier Capo, Josep A. Tur, Antoni Pons and Antoni Sureda
DOI: 10.2174/1568026616666160824102322



Evaluation of the Novel Antichagasic Activity of [1,2,3]Triazolo[1,5-a]pyridine Derivatives

Volume:17   Issue: 4
Pp: 399-411
Michel Lapier, Maria C. Zuniga-Lopez, Benjamin Aguilera-Venegas, Rosa Adam, Belen Abarca, Rafael Ballesteros, Rodrigo Lopez-Munoz, Juan Diego Maya and Claudio Olea-Azar
DOI: 10.2174/1568026616666160824103040



Elucidation of Phosphodiesterase-1 Inhibitory Effect of Some Selected Natural Polyphenolics Using In Vitro and In Silico Methods

Volume:17   Issue: 4
Pp: 412-417
Abdur Rauf, Ilkay Erdogan Orhan, Abdulselam Ertas, Hamdi Temel, Taibi Ben Hadda, Muhammad Saleem, Muslim Raza and Haroon Khan
DOI: 10.2174/1568026616666160824103615



Heterocyclic Compounds: Effective α-Amylase and α-Glucosidase Inhibitors

Volume:17   Issue: 4
Pp: 428-440
Mina Saeedi, Abbas Hadjiakhondi, Seyed Mohammad Nabavi and Azadeh Manayi
DOI: 10.2174/1568026616666160824104655



Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition

Volume:17   Issue: 4
Pp: 441-459
Rosario Randino, Ilaria Moronese, Elena Cini, Valentina Bizzarro, Marco Persico, Manuela Grimaldi, Mario Scrima, Anna Maria D`Ursi, Ettore Novellino, Eduardo Sobarzo-Sánchez, Luca Rastrelli, Caterina Fattorusso, Antonello Petrella, Manuela Rodriquez* and Maurizio Taddei
DOI: 10.2174/1568026616666160824105645



Flavonoids and Chagas' Disease: The Story So Far!

Volume:17   Issue: 4
Pp: 460-466
Seyed Fazel Nabavi, Antoni Sureda, Maria Daglia, Morteza Izadi, Luca Rastrelli and Seyed Mohammad Nabavi
DOI: 10.2174/1568026616666160824110141



Melatonin and Respiratory Diseases: A Review

Volume:17   Issue: 4
Pp: 467-488
Solomon Habtemariam, Maria Daglia, Antoni Sureda, Zeliha Selamoglu, Mehmet Fuat Gulhan and Seyed Mohammad Nabavi
DOI: 10.2174/1568026616666160824120338



A Medical Approach to the Monoamine Oxidase Inhibition by Using 7Hbenzo[ e]perimidin-7-one Derivatives

Volume:17   Issue: 4
Pp: 489-497
Mitchell Bacho, Eduardo Coelho-Cerqueira, Cristian Follmer, Seyed Mohammad Nabavi, Luca Rastrelli, Eugenio Uriarte and Eduardo Sobarzo-Sanchez
DOI: 10.2174/1568026616666160824120929



New Adamantyl Chalcones: Synthesis, Antimicrobial and Anticancer Activities

Volume:17   Issue: 4
Pp: 498-506
Aouatef Tabbi, Dahmane Tebbani, Angelamaria Caporale, Carmela Saturnino, S. F. Nabavi, Palma Giuseppe, Claudio Arra, Zerrin Canturk, Gulhan Turan-Zitouni, Hocine Merazig, Eduardo Sobarzo-Sanchez and Luca Rastrelli
DOI: 10.2174/1568026616666160824121935