Current Topics in Medicinal Chemistry


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA


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Editorial (Thematic Issue: Playing Well with Others! Initiating and Sustaining Successful Collaborations between Industry, Academia and Government) promotion: free to download

Volume:14   Issue: 3
Pp: 291-293
Craig J. Thomas and John C. McKew
DOI: 10.2174/1568026613666131127125351

Open Innovation Drug Discovery (OIDD): A Potential Path to Novel Therapeutic Chemical Space open access plus

Volume:14   Issue: 3
Pp: 294-303
Maria Alvim-Gaston, Timothy Grese, Abdelaziz Mahoui, Alan D. Palkowitz, Marta Pineiro-Nunez and Ian Watson
DOI: 10.2174/1568026613666131127125858

Leveraging Public Private Partnerships to Innovate under Challenging Budget Times

Volume:14   Issue: 3
Pp: 326-329
Lili M. Portilla and Mark L. Rohrbaugh
DOI: 10.2174/1568026613666131127155703

Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease

Volume:14   Issue: 3
Pp: 330-339
Elizabeth A. Ottinger, Mark L. Kao, Nuria Carrillo-Carrasco, Nicole Yanjanin, Roopa Kanakatti Shankar, Marjo Janssen, Marcus Brewster, Ilona Scott, Xin Xu, Jim Cradock, Pramod Terse, Seameen J. Dehdashti, Juan Marugan, Wei Zheng, Lili Portilla, Alan Hubbs, William J. Pavan, John Heiss, Charles H.Vite, Steven U. Walkley, Daniel S. Ory, Steven A. Silber, Forbes D. Porter, Christopher P. Austin and John C. McKew
DOI: 10.2174/1568026613666131127160118

Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS) open access plus

Volume:14   Issue: 3
Pp: 340-342
David H. Drewry, Timothy M. Willson and William J. Zuercher
DOI: 10.2174/1568026613666131127160819

Editorial (Thematic Issue: Genomics and Proteomics behind Drug Design) promotion: free to download

Volume:14   Issue: 3
Pp: 343-343
Yasset Perez-Riverol and Paulo Costa Carvalho
DOI: 10.2174/1568026613666131204101110

Characterization of Protein Complexes using Targeted Proteomics

Volume:14   Issue: 3
Pp: 344-350
Yassel Ramos Gomez, Sebastien Gallien, Vivian Huerta, Jan van Oostrum, Bruno Domon and Luis Javier Gonzalez
DOI: 10.2174/1568026613666131204130124

Regulation by IFN-α/IFN-γ Co-Formulation (HerberPAG®) of Genes Involved in Interferon-STAT-Pathways and Apoptosis in U87MG

Volume:14   Issue: 3
Pp: 351-358
Claudia Bello, Dania Vazquez-Blomquist, Jamilet Miranda, Yanelda Garcia, Lidia Ines Novoa, Daniel Palenzuela and Iraldo Bello
DOI: 10.2174/1568026613666131204125725

Potential Correlation between Tumor Aggressiveness and Protein Expression Patterns of Nipple Aspirate Fluid (NAF) Revealed by Gel-Based Proteomic Analysis

Volume:14   Issue: 3
Pp: 359-368
Giselle Villa Flor Brunoro, Andre Teixeira da Silva Ferreira, Monique Ramos de Oliveira Trugilho, Tamires Sousa de Oliveira, Luis Claudio Belo Amêndola, Jonas Perales, Richard Hemmi Valente, Claudia Vitória de Moura Gallo, Dante Pagnoncelli and Ana Gisele da Costa Neves-Ferreira
DOI: 10.2174/1568026613666131204121854

Using Mass Spectrometry-Based Peptidomics to understand the Brain and Disorders such as Parkinson’s Disease and Schizophrenia

Volume:14   Issue: 3
Pp: 369-381
Cecília Cerqueira Cafe-Mendes, Emer S. Ferro, Luiz Roberto G. Britto and Daniel Martins-de-Souza
DOI: 10.2174/1568026613666131204120747

Proteome Analysis of Formalin-Fixed Paraffin-Embedded Tissues from a Primary Gastric Melanoma and its Meningeal Metastasis: A Case Report

Volume:14   Issue: 3
Pp: 382-387
Juliana de S. da G. Fischer, Nathalie H. S. Canedo, Katia Maria da S. Goncalves, Leila Maria Cardao Chimelli, Monique Franca, Felipe V. Leprevost, Priscila Ferreira Aquino, Paulo C. Carvalho and Maria da Gloria C. Carvalho
DOI: 10.2174/1568026613666131204114218

A Survey of Molecular Descriptors Used in Mass Spectrometry Based Proteomics

Volume:14   Issue: 3
Pp: 388-397
Enrique Audain, Aniel Sanchez, Juan Antonio Vizcaíno and Yasset Perez-Riverol
DOI: 10.2174/1568026613666131204113537

A Practical Guide to Sequencing Genomes and Transcriptomes

Volume:14   Issue: 3
Pp: 398-406
Alejandro Sanchez-Flores and Cei Abreu-Goodger
DOI: 10.2174/1568026613666131204142353

GARM: Genome Assembly, Reconciliation and Merging Pipeline

Volume:14   Issue: 3
Pp: 418-424
Luz Mayela Soto-Jimenez, Karel Estrada and Alejandro Sanchez-Flores
DOI: 10.2174/1568026613666131204110628

Database Construction and Peptide Identification Strategies for Proteogenomic Studies on Sequenced Genomes

Volume:14   Issue: 3
Pp: 425-434
Celine Hernandez, Patrice Waridel and Manfredo Quadroni
DOI: 10.2174/1568026613666131204105652

Bioinformatics Tools for the Functional Interpretation of Quantitative Proteomics Results

Volume:14   Issue: 3
Pp: 435-449
Teresa Nunez Villavicencio-Diaz, Arielis Rodriguez-Ulloa, Osmany Guirola-Cruz and Yasset Perez-Riverol
DOI: 10.2174/1568026613666131204105110

Alterations of the Kidney Cortex Proteome in Response to Exercise Training in Normoglycemic and Hyperglycemic Conditions

Volume:14   Issue: 3
Pp: 450-461
Roger de Moraes, Richard H. Valente, Ileana R. Leon, Monique R.O. Trugilho, Antonio G. Pacheco, Antonio C.L. Nobrega, Marilia B. Gomes, Jonas Perales and Eduardo Tibirica
DOI: 10.2174/1568026613666131204115656