Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Editorial: (Thematic Issue: Medicinal Chemistry of Farnesoid X Receptor (FXR) Modulators: The-State-of-the-Art) free to download

Volume:14   Issue: 19
Pp: 2127-2128
Maura Marinozzi
DOI: 10.2174/1568026614666141112104841

Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands

Volume:14   Issue: 19
Pp: 2129-2142
Andrea Carotti, Maura Marinozzi, Chiara Custodi, Bruno Cerra, Roberto Pellicciari, Antimo Gioiello and Antonio Macchiarulo
DOI: 10.2174/1568026614666141112094058

Knocking on FXR's Door:The "Hammerhead"-Structure Series of FXRs Agonists - Amphiphilic Isoxazoles with Potent In Vitro and In Vivo Activities

Volume:14   Issue: 19
Pp: 2143-2158
Christian Gege, Olaf Kinzel, Christoph Steeneck, Andreas Schulz and Claus Kremoser
DOI: 10.2174/1568026614666141112094430

Bile Acid Derivatives as Ligands of the Farnesoid X Receptor: Molecular Determinants for Bile Acid Binding and Receptor Modulation

Volume:14   Issue: 19
Pp: 2159-2174
Antimo Gioiello, Bruno Cerra, Serena Mostarda, Chiara Guercini, Roberto Pellicciari and Antonio Macchiarulo
DOI: 10.2174/1568026614666141112100208

Medicinal Chemistry and Pharmacological Effects of Farnesoid X Receptor (FXR) Antagonists

Volume:14   Issue: 19
Pp: 2188-2205
Christina Lamers, Manfred Schubert-Zsilavecz and Daniel Merk
DOI: 10.2174/1568026614666141112103516