Current Topics in Medicinal Chemistry


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA


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Editorial (Thematic Issue: Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics) free to download

Volume:13   Issue: 19
Pp: 2395-2396
Giuseppe Legname and Maria Laura Bolognesi
DOI: 10.2174/15680266113136660167

Strain Specificity and Drug Resistance in Anti-Prion Therapy

Volume:13   Issue: 19
Pp: 2397-2406
Lakshmi Miller-Vedam and Sina Ghaemmaghami
DOI: 10.2174/15680266113136660168

NMR Structural Studies of Human Cellular Prion Proteins

Volume:13   Issue: 19
Pp: 2407-2418
Ivana Biljan, Gregor Ilc, Gabriele Giachin, Giuseppe Legname and Janez Plavec
DOI: 10.2174/15680266113136660169

Computational Studies on the Prion Protein

Volume:13   Issue: 19
Pp: 2419-2431
Giulia Rossetti, Salvatore Bongarzone and Paolo Carloni
DOI: 10.2174/15680266113136660170

Logical Design of Medical Chaperone for Prion Diseases

Volume:13   Issue: 19
Pp: 2432-2440
Kazuo Kuwata
DOI: 10.2174/15680266113136660171

Prion Chemical Biology: On the Road to Therapeutics? open access plus

Volume:13   Issue: 19
Pp: 2441-2464
Beining Chen, Mark Thompson, Jennifer Louth and Kai Guo
DOI: 10.2174/15680266113136660172

Therapy in Prion Diseases open access plus

Volume:13   Issue: 19
Pp: 2465-2476
Gianluigi Forloni, Vladimiro Artuso, Ignazio Roiter, Michela Morbin and Fabrizio Tagliavini
DOI: 10.2174/15680266113136660173

Thienyl Pyrimidine Derivatives with PrPSc Oligomer-Inducing Activity are a Promising Tool to Study Prions

Volume:13   Issue: 19
Pp: 2477-2483
Thibaut Imberdis, Adeline Ayrolles-Torro, Jean-Michel Verdier and Véronique Perrier
DOI: 10.2174/15680266113136660174

Hybrid Molecules Synergistically Acting Against Protein Aggregation Diseases

Volume:13   Issue: 19
Pp: 2484-2490
Carsten Korth, Ralf Klingenstein and Andreas Müller-Schiffmann
DOI: 10.2174/15680266113136660175

Modulation of Prion by Small Molecules: From Monovalent to Bivalent and Multivalent Ligands

Volume:13   Issue: 19
Pp: 2491-2503
Matteo Staderini, Giuseppe Legname, Maria Laura Bolognesi and J. Carlos Menéndez
DOI: 10.2174/15680266113136660176

Animal Models for Testing Anti-Prion Drugs

Volume:13   Issue: 19
Pp: 2504-2521
Natalia Fernández-Borges, Saioa R. Elezgarai, Hasier Eraña and Joaquín Castilla
DOI: 10.2174/15680266113136660177

Amyloid-Binding Compounds and their Anti-Prion Potency

Volume:13   Issue: 19
Pp: 2522-2532
Kenta Teruya and Katsumi Doh-ura
DOI: 10.2174/15680266113136660178