Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Editorial (Hot Topic: Synthetic, Natural and Related Compounds: New Approach to Chronic Diseases Studies) free to download

Volume:12   Issue:19
Pp: 2035-2036
Fátima Regina Mena Barreto Silva and Luisa Helena Cazarolli
DOI: 10.2174/1568026611212190001

Docking, Synthesis and Anti-Diabetic Activity of Novel Sulfonylhydrazone Derivatives Designed as PPAR-Gamma Agonists

Volume:12   Issue:19
Pp: 2037-2048
Gisele Zapata-Sudo, Lidia M. Lima, Sharlene L. Pereira, Margarete M. Trachez, Filipe P. da Costa, Beatriz J. Souza, Carlos E. S. Monteiro, Nelilma C. Romeiro, Everton D. D’Andrea, Roberto T. Sudo and Eliezer J. Barreiro
DOI: 10.2174/1568026611212190002

Acylhydrazones Contribute to Serum Glucose Homeostasis Through Dual Physiological Targets

Volume:12   Issue:19
Pp: 2049-2058
Marisa Jadna Silva Frederico, Allisson Jhonatan Gomes Castro, Alessandra Mascarello, Camila Pires Mendes, Virginia Dermachi Kappel, Taisa Regina Stumpf, Paulo Cesar Leal, Ricardo Jose Nunes, Rosendo Augusto Yunes and Fatima Regina Mena Barreto Silva
DOI: 10.2174/1568026611212190003

Estrogen Receptor 1 Agonist PPT Stimulates Slc2a4 Gene Expression and Improves Insulin-Induced Glucose Uptake in Adipocytes

Volume:12   Issue:19
Pp: 2059-2069
R. S. Campello, A. B. Alves-Wagner, T. F. Lucas, R. C. Mori, D. T. Furuya, C. S. Porto and U. F. Machado
DOI: 10.2174/1568026611212190004

The Central Nervous System as a Promising Target to Treat Diabetes Mellitus open access plus

Volume:12   Issue:19
Pp: 2070-2081
Jose Donato Jr.
DOI: 10.2174/1568026611212190005

Equinatoxin II Potentiates Temozolomide- and Etoposide-Induced Glioblastoma Cell Death

Volume:12   Issue:19
Pp: 2082-2093
Suzana Assad Kahn, Deborah Biasoli, Celina Garcia, Luiz Henrique M. Geraldo, Bruno Pontes, Morgana Sobrinho, Ana Carina Bon Frauches, Luciana Romao, Rossana C. Soletti, Fernando dos Santos Assuncao, Fernanda Tovar-Moll, Jorge Marcondes de Souza, Flavia R.S. Lima, Gregor Anderluh and Vivaldo Moura-Neto
DOI: 10.2174/1568026611212190006

Biological Evaluation of 3-Acyl-2-Arylamino-1,4-Naphthoquinones as Inhibitors of Hsp90 Chaperoning Function

Volume:12   Issue:19
Pp: 2094-2102
David Rios, Julio Benites, Jaime A. Valderrama, Mirelle Farias, Rozangela C. Pedrosa, Julien Verrax and Pedro Buc Calderon
DOI: 10.2174/1568026611212190007

Effects of Natural Compounds on Xenopus Embryogenesis: A Potential Read Out for Functional Drug Discovery Targeting Wnt/β-catenin Signaling open access plus

Volume:12   Issue:19
Pp: 2103-2113
Nathalia G. Amado, Barbara F. Fonseca, Debora Malta Cerqueira, Alice H. Reis, Alessandro Bolis Costa Simas, Ricardo Machado Kuster, Fabio A. Mendes and Jose G. Abreu
DOI: 10.2174/1568026611212190008