Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Editorial [Hot topic: G-Protein Coupled Receptors: Drug Targets of Key Importance (Guest Editors: Luca Piali and Christoph Boss)] promotion: free to download

Volume:11   Issue: 6
Pp: 608-608
Luca Piali and Christoph Boss
DOI: 10.2174/1568026611109060608

EBI2, GPR18, and GPR17 – Three Structurally Related but Biologically Distinct 7TM Receptors

Volume:11   Issue: 6
Pp: 618-628
Kristine Norregaard, Tau Benned-Jensen and Mette Marie Rosenkilde
DOI: 10.2174/1568026611109060618

Novel Anti-Inflammatory-Pro-Resolving Mediators and Their Receptors

Volume:11   Issue: 6
Pp: 629-647
Charles N. Serhan, Sriram Krishnamoorthy, Antonio Recchiuti and Nan Chiang
DOI: 10.2174/1568026611109060629

The Evolution of Histamine H3 Antagonists/Inverse Agonists

Volume:11   Issue: 6
Pp: 648-660
Evan P. Lebois, Carrie K. Jones and Craig W. Lindsley
DOI: 10.2174/1568026611109060648

Molecular Determinants of Selective Agonist and Antagonist Binding to the Histamine H4 Receptor

Volume:11   Issue: 6
Pp: 661-679
Enade P. Istyastono, Chris de Graaf, Iwan J.P. de Esch and Rob Leurs
DOI: 10.2174/1568026611109060661

mGluR5 Negative Allosteric Modulators Overview: A Medicinal Chemistry Approach Towards a Series of Novel Therapeutic Agents

Volume:11   Issue: 6
Pp: 680-695
Jean-Philippe Rocher, Beatrice Bonnet, Christelle Bolea, Robert Lutjens, Emmanuel Le Poul, Sonia Poli, Mark Epping-Jordan, Anne-Sophie Bessis, Bernard Ludwig and Vincent Mutel
DOI: 10.2174/1568026611109060680

Discovery of Dual Orexin Receptor Antagonists (DORAs) for the Treatment of Insomnia

Volume:11   Issue: 6
Pp: 696-725
Paul J. Coleman, Christopher D. Cox and Anthony J. Roecker
DOI: 10.2174/1568026611109060696

Synthetic Sphingosine 1-Phosphate Receptor Modulators - Opportunities and Potential Pitfalls

Volume:11   Issue: 6
Pp: 726-757
Martin H. Bolli, Cyrille Lescop and Oliver Nayler
DOI: 10.2174/1568026611109060726