Current Topics in Medicinal Chemistry


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA


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Abstract Ahead of Print

A Possible Modulation Mechanism of Intramolecular and Intermolecular Interactions for NCAM Polysialylation and Cell Migration

Bo Lu, Xue-Hui Liu, Si-Ming Lia, Zhi-Long Lu, Dong Chen, Frederic A. Troy II, Ri-Bo Huang and Guo-Ping Zhou*

A study for therapeutic treatment against Parkinson’s Disease via Chou’s 5-steps rule

Jianqiang Lan, Jinqiang Liu, Chenghong Liao, David J. Merkler, Qian Han* and Jianyong Li*

Synthesis of coumarin derivatives as versatile scaffolds for GSK-3β enzyme inhibition

Carla S. Franciscoa, Clara L. Javarini, Iatahanderson de S. Barcelos , Pedro A. B. Morais, Heberth de Paula, Warley de S. Borges, Álvaro Cunha Neto and Valdemar Lacerda Jr.*

Novel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum

Kamilla Rodrigues Rogerio, Cedric Stephan Graebin, Luiza Helena Pinto Domingues, Luana Santos Oliveira, Vitoria de Souza Fernandes da Silva, Claudio Tadeu Daniel-Ribeiro, Leonardo J. M. Carvalho and Nubia Boechat*

Biological production of (S)-acetoin: a state-of-the-art review

Neng-Zhong Xie*, Jian-Xiu Li and Ri-Bo Huang*

Recent Advances in Ginsenosides as Potential Therapeutics Against Breast Cancer

Yu-hang Guo, Revathimadhubala Kuruganti and Ying Gao*

Identifying cancer targets based on machine learning methods via Chou’s 5-steps rule and general pseudo components

Ruirui Liang, Jiayang Xie, Chi Zhang, Mengying Zhang, Hai Huang, Haizhong Huo, Xin Cao and Bing Niu*

The Present and Future of Novel Protein Degradation Technology

Liwen Xia, Wei Liu, Yinsen Song, Hailiang Zhu and Yongtao Duan*

Targeting Protein-Protein Interaction with Covalent Small-Molecule Inhibitors

Bingbing Li, Deqin Rong and Yuanxiang Wang*

STING Activation and Its Application in Immuno-Oncology

Yiqian Liana*, Kevin J. Duffya and Jingsong Yang

Differences in kynurenine metabolism during depressive, manic, and euthymic phases of bipolar affective disorder

Alexander Maget, Martina Platzer*, Susanne A. Bengesser, Frederike T. Fellendorf, Armin Birner, Robert Queissner, Carlo Hamm, Bernd Reininghaus, Andrzej Hecker, Lukas Tomberger, Renè Pilz, Nina Dalkner, Natalie Moll, Gregor Schütze, Markus Schwarz, Hans P. Kapfhammer and Eva Z. Reininghaus