Current Topics in Medicinal Chemistry

Editor-in-Chief:

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Abstract Ahead of Print

Griseofulvin derivatives: Synthesis, molecular docking and biological evaluation

Volume:19
Victor Kartsev, Athina Geronikaki*, Anthi Petrou, Boris Lichitsky, Marina Kostic, Marija Smiljkovic, Marina Soković and Samvel Sirakanyan

Unfolded Protein Response as a Therapeutic Target in Cardiovascular Disease

Volume:19
Guangyu Zhang, Xiaoding Wang, Thomas G. Gillette, Yingfeng Deng and Zhao V. Wang*

A Computer - Aided Drug Designing for Pharmacological inhibition of ALK inhibitors induces apoptosis and differentiation in Non-small cell lung cancer

Volume:19
Saphy Sharda, Ravina Khandelwal, Ritu Adhikary, Diksha Sharma, Manisha Majhi, Tajamul Hussain, Anuraj Nayarisseri* and Sanjeev Kumar Singh*

Sperm quality in mouse after exposure to low doses of TCDD

Volume:19
Heba Yehia Anwar Elsayed, Esvieta Tenorio Borroto*, Alberto Barbabosa Pliego, Jorge Acosta Dibarrat, Fabiola Rivera Ramirez, Juan Carlos Vázquez Chagoyán, Nazario Pescador Salas and Hector Diaz-Albiter

Identification of essential 2D and 3D chemical features for discovery of the novel tubulin polymerization inhibitors

Volume:19
Fateme Azimi, Jahan B. Ghasemi*, Lotfollah Saghaei, Farshid Hassanzadeh, Mohammad Mahdavi, Hojjat Sadeghi-Aliabadi, Marcus T. Scotti and Luciana Scotti*

Recent Progress on Discovery of Sirt2 Inhibitors for the Treatment of Various Cancers

Volume:19
Ting Wang, Zhuyu Xu, Yongping Lu, Baowen Qi*, Lan Bai*, Wenbo Liu, Chengchen Zhang and Zhongliang Jiang

Ensemble-based modeling of chemical compounds with antimalarial activity

Volume:19
Ana Yisel Caballero-Alfonso, Maykel Cruz-Monteagudo, Eduardo Tejera, Emilio Benfenati, Fernanda Borges, M. Natália D. S. Cordeiro, Vinicio Armijos-Jaramillo and Yunierkis Perez-Castillo*

Higher-Order and Mixed Discrete Derivatives like a Novel Graph-Theoretical Invariant for Generating New Molecular Descriptors

Volume:19
Oscar Martínez-Santiago, Yovani Marrero-Ponce*, Ricardo Vivas-Reyes, Mauricio E. Orozco Ugarriza, Elízabeth Hurtado-Rodríguez, Yoan Martínez-López, F. Javier Torres, Cesar H. Zambrano and Hai Pham‑The

New mechanistic insight on the PIM-1 kinase inhibitor AZD1208 using multidrug resistant human erythroleukemia cell lines and molecular docking simulations

Volume:19
Maiara Bernardes Marques*, Michael González-Durruthy*, Bruna Félix da Silva Nornberg, Bruno Rodrigues Oliveira, Daniela Volcan Almeida, Ana Paula de Souza Votto and Luis Fernando Marins

Antihyperalgesic activity of quillaic acid obtained from Quillaja saponaria Mol.

Volume:19
Sylvia Arrau, Maité Rodríguez-Díaz, Bruce K. Cassels, Gabriela Valenzuela-Barra, Carla Delporte*, Andrés Barriga and Hugo F. Miranda*