Abstract
The development of novel new generation vaccine systems that is based on proteins, peptides or DNA is of great current interest. However, due to the lower efficiencies of these new generation vaccines, they are seldomly used alone. Rather, their formulations often contain adjuvants, either to enhance the immune responses or to reduce dosing. The present chapter will provide a brief overview of the recent advances in peptide-based cancer vaccine adjuvants, focusing mainly on Liposome-Protamine-DNA (LPD) nanoparticle-mediated antigen delivery.
Keywords: immunogens, cancer vaccines, peptide antigen, mhc molecule, antigen presenting cells (apc), anti-tumor
Current Drug Delivery
Title: Lipid-Protamine-DNA-Mediated Antigen Delivery
Volume: 2 Issue: 4
Author(s): Dileep P. Vangasseri, Su-Ji Han and Leaf Huang
Affiliation:
Keywords: immunogens, cancer vaccines, peptide antigen, mhc molecule, antigen presenting cells (apc), anti-tumor
Abstract: The development of novel new generation vaccine systems that is based on proteins, peptides or DNA is of great current interest. However, due to the lower efficiencies of these new generation vaccines, they are seldomly used alone. Rather, their formulations often contain adjuvants, either to enhance the immune responses or to reduce dosing. The present chapter will provide a brief overview of the recent advances in peptide-based cancer vaccine adjuvants, focusing mainly on Liposome-Protamine-DNA (LPD) nanoparticle-mediated antigen delivery.
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Cite this article as:
Vangasseri P. Dileep, Han Su-Ji and Huang Leaf, Lipid-Protamine-DNA-Mediated Antigen Delivery, Current Drug Delivery 2005; 2 (4) . https://dx.doi.org/10.2174/156720105774370168
DOI https://dx.doi.org/10.2174/156720105774370168 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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