Abstract
Recent progress in gene therapy has increased the need for non-invasive imaging methods that would allow early diagnosis of successful treatment. Magnetic resonance methods, magnetic resonance imaging (MRI) and spectroscopy (MRS), have shown great promise to achieve this goal. The current mini-review describes recent advances in experimental MRI and MRS to detect individual treatment steps in gene therapy of tumours from gene transfection to therapy response. Limitations of the current techniques are also discussed.
Keywords: Diffusion, relaxation, T1r, lipids, molecular imaging
Current Gene Therapy
Title: Tumour Gene Therapy Monitoring Using Magnetic Resonance Imaging and Spectroscopy
Volume: 5 Issue: 6
Author(s): Mikko I. Kettunen and Olli H.J. Grohn
Affiliation:
Keywords: Diffusion, relaxation, T1r, lipids, molecular imaging
Abstract: Recent progress in gene therapy has increased the need for non-invasive imaging methods that would allow early diagnosis of successful treatment. Magnetic resonance methods, magnetic resonance imaging (MRI) and spectroscopy (MRS), have shown great promise to achieve this goal. The current mini-review describes recent advances in experimental MRI and MRS to detect individual treatment steps in gene therapy of tumours from gene transfection to therapy response. Limitations of the current techniques are also discussed.
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Cite this article as:
Kettunen I. Mikko and Grohn H.J. Olli, Tumour Gene Therapy Monitoring Using Magnetic Resonance Imaging and Spectroscopy, Current Gene Therapy 2005; 5 (6) . https://dx.doi.org/10.2174/156652305774964686
DOI https://dx.doi.org/10.2174/156652305774964686 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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Programmed Cell Death (PCD) is recognized as a pivotal biological mechanism with far-reaching effects in the realm of cancer therapy. This complex process encompasses a variety of cell death modalities, including apoptosis, autophagic cell death, pyroptosis, and ferroptosis, each of which contributes to the intricate landscape of cancer development and ...read more
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