Current Pharmaceutical Biotechnology

Editor-in-Chief

Nikolaos Labrou
Department of Biotechnology
Agricultural University of Athens
Athens
(Greece)

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Articles Ahead of Print

The P-MAPA immunomodulator partially prevents apoptosis induced by Zika virus infection in THP-1 cells

Volume:21
Morganna C. Lima, Elisa A. N. Azevedo, Clarice N. L. de Morais, Larissa I. O. de Sousa, Bruno M. Carvalho, Iseu N. da Silva and Rafael F. O. Franca*

Oleophylic Nanospheres Self-Assembly by Emulsion Technique Utilizing the Automatic Nanoscalar Interfacial Alternation (ANIAE)

Volume:21
Hao Ran, Weibin Liu, Xin Pan, Chuanbin Wu*, Guilan Quan, Ying Huang and Yingtong Cui

Global Trends in Cannabis and Cannabidiol Research from 1940 to 2019

Volume:21
Jingting Liu, Haimei Chen, Steven Newmaster, Shubin Wang and Chang Liu*

Potential Pharmaceutical and Food Applications of Postbiotics: A Review

Volume:21
Aziz Homayouni Rad, Amin Abbasi*, Hossein Samadi Kafil and Khudaverdi Ganbarov

Influence of the Intestinal Microbiota on Diabetes Management

Volume:21
Eva Alvarez-Vieites, Aroa López-Santamarina, José Manuel Miranda, Alicia del Carmen Mondragón, Alexandre Lamas, Alejandra Cardelle-Cobas, Carolina Nebot, Carlos Manuel Franco* and Alberto Cepeda

Noncoding RNAs in Medicinal Plants and Their Regulatory Roles in Bioactive Compound Production

Volume:21
Caili Li, Meizhen Wang, Xiaoxiao Qiu, Hong Zhou and Shanfa Lu*

Role of P-gp and HDAC2 and their Reciprocal Relationship in Uncontrolled Asthma

Volume:21
Ravi Mishra, Rachna Chaturvedi, Zia Hashim*, Alok Nath, Ajmal Khan, Mansi Gupta, Harshit Singh and Vikas Agarwal

Saponins from the Sea Cucumber Promote the Osteoblast Differentiation in MC3T3-E1 Cells through the Activation of the BMP2/ Smads Pathway

Volume:21
Zhuo Li*, Yingying Tian, Hongge Ma, Meiling Wang, Ziyi Yan, Changhu Xue and Jingfeng Wang

Proteomics Analysis of Trastuzumab Toxicity in the H9c2 Cardiomyoblast Cell Line and its Inhibition by Carvedilol

Volume:21
Elham Beiranvand, Fatemeh Torkashvand, Seyed Nasser Ostad, Mehdi Mirzaie, Esmat Mirabzadeh Ardakani, Fatemeh Zandi, Soroush Sardari, Ghasem Hosseini Salekdeh, Mohammad Ali Shokrgozar and Behrouz Vaziri*

The Influence of Salinomycin on the Expression Profile of mRNAs Encoding Selected Caspases and MiRNAs Regulating their Expression in Endometrial Cancer Cell Line

Volume:21
Krzysztof Januszyk*, Piotr Januszyk, Beniamin Oskar Grabarek, Dariusz Boroń and Marcin Oplawski

Cisplatin Changes Expression of SEMA3B in Endometrial Cancer

Volume:21
Wojciech Peszek*, Piotr Kras, Beniamin Oskar Grabarek, Dariusz Boroń and Marcin Oplawski

Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line

Volume:21
Kamil Kiełbasiński*, Wojciech Peszek, Beniamin Oskar Grabarek, Dariusz Boroń, Magdalena Wierzbik-Strońska and Marcin Oplawski

Targeted Photodynamic Therapy (PDT) of Lung Cancer with Biotinylated Silicon (IV) Phthalocyanine

Volume:21
Wenyi Dong, Ke Li, Shijie Wang, Ling Qiu, Qingzhu Liu, Minhao Xie and Jianguo Lin*

Bioactive Molecules from the Alpinia Genus: A Comprehensive Review

Volume:21
Santwona Dash, Manasa Kumar Panda, Mayanglambam Chandrakumar Singh, Bimal Prasad Jit, Yengkhom Disco Singh and Jayanta Kumar Patra*

Novel Therapeutic Approaches and Targets for the Treatment of Suppurativa Hidradenitis

Volume:21
Roberta Giuffrida, Serafinella Patrizia Cannavò, Marialorena Coppola and Claudio Guarneri*

Cytotoxic and Antibiotic Potential of Secondary Metabolites from the Lichen Umbilicaria muhlenbergii

Volume:21
Lyndon Letwin, Ladislav Malek, Zacharias Suntres and Lew Christopher*

Protective Effects of Cocos Nucifera Oil in Paraphenylene Diamine Toxicity

Volume:21
El-Shaimaa A. Arafa, Manal Ali Buabeid*, Waseem Hassan, Ghulam Murtaza, Tahir Ali Chohan and Hammad Ahmed

Tinospora cordifolia (Giloy): Phytochemistry, Ethnopharmacology, Clinical Application and Conservation Strategies

Volume:21
Pradeep Kumar*, Madhu Kamle, Dipendra Kumar Mahato, Himashree Bora, Bharti Sharma, Prasad Rasane and Vivek K. Bajpai

Lichens in Genus Parmelia: An Overview and their Application

Volume:21
Arumugam Dhanesh Gandhi, Sivaji Sathiyaraj, Gunasekaran Suriyakala, Sivakumar Saranya, Tirumalpur Neelakandan Baskaran, Balasubramani Ravindran and Ranganathan Babujanrthanam*

The Role of the Coagulase-negative Staphylococci (CoNS) in Infective Endocarditis; a Narrative Review from 2000 to 2020

Volume:21
Mohammad Ali Noshak*, Mohammad Ahangarzadeh Rezaee, Alka Hasani and Mehdi Mirzaii

Molecular Profiling of Human Induced Pluripotent Stem Cell-Derived Cells and their Application for Drug Safety Study

Volume:21
Toshikatsu Matsui, Norimasa Miyamoto, Fumiyo Saito and Tadahiro Shinozawa*

MicroRNA: Promising Roles in Cancer Therapy

Volume:21
Atieh Hashemi* and Gilar Gorji-bahri

The Effect of Cyclosporine A on Dermal Fibroblast Cell – Transcriptomic Analysis of Inflammatory Response Pathway

Volume:21
Grażyna Janikowska*, Ewa Kurzeja, Marcin Janikowski, Barbara Strzałka-Mrozik, Alina Pyka-Pająk and Tomasz Janikowski

Ethnopharmacological Applications of Mango (Mangiferaindica L.) Peel - A Review

Volume:21
Katike Umamahesh*, Arumugam Dhanesh Gandhi and Obulam Vijaya Sarathi Reddy

Differences in the Expression Pattern of mRNA Protein SEMA3F in Endometrial Cancer in vitro under Cisplatin Treatment

Volume:21
Przemysław Kieszkowski*, Dariusz Dąbruś, Beniamin Oskar Grabarek and Dariusz Boroń

Morusin Inhibits Human Osteosarcoma via the PI3K-AKT Signaling Pathway

Volume:21
Yong Zhang, Qiuyan Weng, Jianming Chen and Jinming Han*

Apigenin Alleviates Renal Fibroblast Activation through AMPK and ERK Signaling Pathways In Vitro

Volume:21
Ningning Li, Jinzhong Zhang, Tao Sun, Yanfei Lei, Xianghua Liu and Zhenzhen Li*

Analysis of the Clinical Diagnostic Value of GMFB in Cerebral Infarction

Volume:21
Zhaohu Yuan*, Zhiwu Yu, Yiyu Zhang and Huikuan Yang

In Silico Elucidation of the Plausible Inhibitory Potential of Withaferin A of Withania Somnifera Medicinal Herb Against Breast Cancer Targeting Estrogen Receptor

Volume:21
M. Ajmal Ali*, Mohammad Abul Farah*, Khalid M. Al-Anazi, Syed Hussain Basha, Fang Bai, Joongku Lee, Fahad M.A. Al-Hemaid, Ahmed Hossam Mahmoud and Waleed A.Q. Hailan

Thymoquinone, an Active Compound of Nigella Sativa: Role in Prevention and Treatment of Cancer

Volume:21
Saleh A. Almatroodi, Ahmad Almatroudi, Mohammed A. Alsahli, Amjad Ali Khan and Arshad Husain Rahmani*

A Systematic Review and Meta-Analysis: The Effectiveness of Probiotics for Viral Gastroenteritis

Volume:21
Fereshteh Ansari, Fariba Pashazadeh, Elaheh Nourollahi, Sakineh Hajebrahimi, Zachary Munn and Hadi Pourjafar*

Delonix regia a Folklore Remedy for Diabetes; Attenuates Oxidative Stress and Modulates Type II Diabetes Mellitus

Volume:21
Darosham Khan, Ali Sharif*, Mehroz Zafar, Bushra Akhtar, Muhammad Furqan Akhtar and Sana Awan

MiR-493 Induces Cytotoxic Autophagy in Prostate Cancer Cells through Regulation on PHLPP2

Volume:21
Jun Deng, Ming Ma , Wei Jiang, Liangliang Zheng and Suping Cui *

Tripterine: A Potential Anti-Allergic Compound

Volume:21
Bao-jun Zhu, Ze-quan Qian, Hui-run Yang and Ru-xia Li*

Altered Expression of MicroRNAs in the Bone Marrow of Multiple Myeloma Patients and their Relationship to Cytogenetic Aberrations

Volume:21
Hanaa R.M. Attia*, Amany H. Abdelrahman, Mona Hamed Ibrahim, Maha M. Eid, Ola M. Eid, Mohamed T. Sallam, Mosaad M. El Gammal and Mahmoud M. Kamel

A Comprehensive Insight Towards Pharmaceutical Aspects of Graphene Nanosheets

Volume:21
Fatemeh Emadi, Arash Emadi and Ahmad Gholami*

Effects and Mechanism of Chlorogenic Acid on Weight Loss

Volume:21
Yanchun Zhong, Yueling Ding, Laiqing Li, Meina Ge, Guangguo Ban, Hongxia Yang, Jun Dai and Licheng Zhang*

Anticancer Potential of Calli Versus Seedling Extracts Derived from Rosmarinus officinalis and Coleus hybridus

Volume:21
Sarah Albogami*, Hadeer Darwish , Hala Abdelmigid , Saqer Alotaibi, Ahmed Nour El-Deen, Alaa Alnefaie and Afnan Alattas

Current Prospects of Nutraceuticals: A Review

Volume:21
Vedant Sachdeva, Arpita Roy and Navneeta Bharadvaja*

Oral Supplements of Ginkgo biloba Extract Alleviate Neuroinflammation, Oxidative Impairments and Neurotoxicity in Rotenone-Induced Parkinsonian Rats

Volume:21
Nema Mohammed, Heba Abdou, Amina Essawy*, Mona Tass, Manal Alfwuaires and Ashraf Abdel-Moneim

Curcumin Therapeutic Modulation of the Wnt Signaling Pathway

Volume:21
Amirhossein Sahebkar*, Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohamamdinejad, Habib Yaribeygi, Maria-Corina Serban and Hossein M. Orafai

Should the Vancomycin Minimal Inhibitory Concentration be used as an Infant Critical Care Regular Criteria?

Volume:21
Nadielle Bidu, Bruno Fernandes, Jucelino Conceição Filho, Regina Bastos, Joice Pedreira and Ricardo David Couto*

TNF Receptor: Fc Fusion Protein Downregulates RANKL/OPG Ratio by Inhibiting CXCL16/CXCR6 in Active Ankylosing Spondylitis

Volume:21
Peiyi Zhang, Shufen Zhou, Zhe Chen, Ye Tian, Qianqian Wang, Hui Li, Tiantian Zhang, Qin Guo, Meiying Wang and Chengshan Guo*

Folate-modified Graphene Oxide as the Drug Delivery System to Load Temozolomide

Volume:21
Li-Hua Wang, Jia-Yuan Liu, Lin Sui, Peng-Hui Zhao, Hai-Di Ma, Zhen Wei* and Yong-Li Wang*

Effects of Succinic Acid Supplementation on Stable Cell Line Growth, Aggregation, and IgG and IgA Production

Volume:21
Victoria Argentova*, Teimur Aliev, Dmitry Dolgikh and M.P. Kirpichnikov

Biological Activities and Phenolic Compound Content of Astilboides tabularis (Hemsl.) Engler Extracts

Volume:21
Jinfeng Yang , Lee Chanok, Kim Heekyu, Yong Soo Kwon and Myong Jo Kim*

Matrix Metalloproteinase 9 is Regulated by LOX-1 and erk1/2 Pathway in Dental Peri-Implantitis

Volume:21
Qian Zhang, Haitao Xu, Na Bai, Fei Tan, Huirong Xu and Jie Liu*

Synergistic Effect of Tazobactam on Amikacin MIC in Acinetobacter baumannii Isolated from Burn Patients in Tehran, Iran

Volume:21
Leila Azimi, Sahel Valadan Tahbaz, Reza Alaghehbandan, Farank Alinejad* and Abdolaziz Rastegar Lari

The Effects of X-Ray Irradiation on Safety and Nutritional Value of Food: a Systematic Review Article

Volume:21
Zakiyeh Balouch Zehi, Asma Afshari, Seyyed Mohammad Ali Noori, Behrooz Jannat and Mohammad Hashemi*

Prevalence of Multi-Drug Resistant Tuberculosis among Tuberculosis Patients Attending Chest Clinics in Osun-State, Nigeria

Volume:21
Oyedeji Jimoh Gbadebo, Adeyemo Charles, Dissou Affolabi, Abiodun Tope, Alli Oyebode, Onaolapo James Olakunle, Onaolapo Yetunde Adejoke, Adesiji Yemisi and Olowe Olugbenga Adekunle*

Expression Profiles of MicroRNAs in Stem Cells Differentiation

Volume:21
Hadi Rajabi, Somayeh Aslani, Alireza Abhari* and Davoud Sanajou

Development of Poly (Methyl vinyl ether-alt-maleic acid) Microneedles for Transdermal Delivery of Atorvastatin Calcium

Volume:21
Pablo Serrano Castañeda, Clara Luisa Domínguez Delgado, Isabel Marlen Rodríguez Cruz, Luz María Melgoza Contreras, Eva María Molina Trinidad, Miriam López Cervantes and José Juan Escobar-Chávez*

Screening of an Alkaline CMCase-Producing Strain and the Optimization of Its Fermentation Condition

Volume:21
Junmei Zhou, Lianghong Yin*, Chenbin Wu, Sijia Wu, Jidong Lu, Hailing Fang and Yongchang Qian*

Oral Biofilm on Dental Materials Among Khat Chewers

Volume:21
Mohammed M Al Moaleem*, Amit Porwal, Nasser M Al Ahmari and Mansoor Shariff

Enhancing the Antibacterial Activity of Erythromycin with Titanium Dioxide Nanoparticles against MRSA

Volume:21
Kaleem Ullah, Shujaat Ali Khan, Abdul Mannan, Romana Khan, Ghulam Murtaza* and Muhammad Arfat Yameen*

Monocyclic Peptides: Types, Synthesis and Applications

Volume:21
Yalda Khazaei-poul, Shohreh Farhadi, Sepideh Ghani, Safar Ali Ahmadizad and Javad Ranjbari*

Plant Phenolics as Pathogen-Carrier Immunogenicity Modulator Haptens

Volume:21
Irais Castillo-Maldonado , María-de-la-Luz Sevilla-González , Dealmy Delgadillo-Guzmán , Agustina Ramírez-Moreno , Nidia Cabral-Hipólito , Mario-Alberto Rivera-Guillén , Luis-Benjamín Serrano-Gallardo, María-del-Carmen Vega-Menchaca and David Pedroza-Escobar *

Icariin Stimulates hFOB 1.19 Osteoblast Proliferation and Differentiation via OPG/RANKL Mediated by the Estrogen Receptor

Volume:21
Lin-Jun Sun, Chong Li, Xiang-hao Wen, Lu Guo, Zi-Fen Guo, Lan-qing Liao and Yu Guo*

Green Synthesis of Silver Nanoparticles Using Artocarpus hirsutus Seed Extract and its Antibacterial Activity

Volume:21
S. Shobana, S. Veena, S. S. M. Sameer, K. Swarnalakshmi and L. A. Vishal*

The Application of HL60-IL-6 Assay for in vitro Pyrogen Detection of CAR-T Cells Products

Volume:21
Can Wang*, Mingren Wang, Gaomin Li, Ziqiang Wang, Hong Shao and Gang Chen

Blending of PLGA-PEG-PLGA for Improving the Erosion and Drug Release Profile of PCL Microspheres

Volume:21
Siyuan Wang, Xiaobo Feng, Ping Liu, Youxiu Wei and Baojun Xiao*