Current Pharmaceutical Design

Editor-in-Chief:

William A. Banks  
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Building 1, Room 810A
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Seattle, WA 98108
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Ahead of Print Article(s)

Circulating Matrix Metalloproteinase-9 Levels in Patients with Systemic Lupus Erythematosus: A Meta-analysis

Volume:24
Yan-Mei Mao, Song Wang, Chan-Na Zhao, Qian Wu, Yi-Lin Dan, Shi-Yang Guan, Tian-Tian LV, Li-Na Liu, Peng Wang and Hai-Feng Pan*

Pure Polyphenols Applications for Cardiac Health and Disease

Volume:24
Claudia N Santos, Andreia Gomes, Carole Oudot, Daniela Dias-Pedroso, Ana Rodriguez-Mateos, Helena L.A. Vieira and Catherine Brenner*

Correlation of Salusin Beta with hs-CRP and ADMA in Hypertensive Children and Adolescents

Volume:24
Urszula Kolakowska, Elzbieta Kuroczycka –Saniutycz, Witold Olanski and Anna Wasilewska*

The Role of Cancer-associated Fibroblasts in Tumorigenesis of Gastric Cancer

Volume:24
Zhilong Ma, Min Chen, Xiaohu Yang, Bin Xu, Zhenshun Song, Bo Zhou* and Tingsong Yang*

Current Perspectives Regarding Stem Cell-based Therapy for Ischemic Stroke

Volume:24
Young Seok Park*, Joo Won Lee, Ho-Beom Kwon and Kyeong-Ah Kwak

Combination of SGLT-2 Inhibitors and GLP-1 Receptor Agonists: Potential Benefits in Surrogate and Hard Endpoints

Volume:24
Michael Doumas, Κonstantinos Imprialos, Konstantinos Stavropoulos, Andromachi Reklou, Alexandros Sachinidis and Vasilios G. Athyros*

The Efficacy of Omega-3 Supplement on Prevention of Retinopathy of Prematurity in Premature Infants: A Randomized Double-blinded Controlled trial

Volume:24
Nasrin Khalesi, Arash Bordbar, Nastaran Khosravi, Morteza Kabirian and Alireza Karimi*

Process Intensification Techniques for the Production of Nano- and Submicronic Particles for Food and Medical Applications

Volume:24
Marco Stoller*, Luca Di Palma, Srikanth Vuppala, Nicola Verdone and Giorgio Vilardi

Recent Advances in Nanosuspension Technology for Drug Delivery

Volume:24
Daisy Arora, Bharat Khurana, Goutam Rath, Sanju Nanda and Amit K. Goyal*

Biological and In silico Studies on Synthetic Analogues of Tyrosine Betaine as Inhibitors of Neprilysin - A Drug Target for the Treatment of Heart Failure

Volume:24
Daniel Fabio Kawano*, Marcelo Rodrigues de Carvalho, Mauricio Ferreira Marcondes Machado, Adriana Karaoglanovic Carmona, Gilberto Ubida Leite Braga and Ivone Carvalho

Polyphenols, their Metabolites and Derivatives as Drug Leads

Volume:24
Filipa A. Almeida, Cláudia Nunes dos Santos and Maria Rita Ventura*

Technetium-99m-based Radiopharmaceuticals in Sentinel Lymph Node Biopsy: Gynecologic Oncology Perspective

Volume:24
Kamil Zalewski*, Malgorzata Benke, Bartlomiej Mirocha, Jakub Radziszewski, Magdalena Chechlinska and Magdalena Kowalewska

Hydroxytyrosol: Emerging Trends in Potential Therapeutic Applications

Volume:24
Maria Carmen Lopez de las Hazas, Laura Rubio*, Alba Macia and Maria Jose Motilva

The Emerging Roles of the HERC Ubiquitin Ligases in Cancer

Volume:24
Xinliang Mao*, Gautam Sethi, Zubin Zhang and Qi Wang

Recent Trends in Nanocrystals for Pharmaceutical Applications

Volume:24
Leming Sun*, Yanzi Hu and Lianbing Zhang*

Exploiting Significance of Physical Exercise in Prevention of Gastrointestinal Disorders

Volume:24
Jan Bilski, Agnieszka Mazur-Bialy, Marcin Magierowski, Slawomir Kwiecien, Dagmara Wojcik, Agata Ptak-Belowska, Marcin Surmiak, Aneta Targosz, Katarzyna Magierowska and Tomasz Brzozowski*

Nanocrystals Technology for Pharmaceutical Science

Volume:24
Zhongyao Cheng, Yumei Lian, Zul Kamal , Xin Ma, Jianjun Chen, Xinbo Zhou *, Jing Su* and Mingfeng Qiu*

Crystal Engineering: Upcoming Paradigm for Efficacious Pulmonary Drug Delivery

Volume:24
Preshita P. Desai, Sanyat S. Mapara and Vandana B. Patravale*

The Effects of Polymorphism on Physicochemical Properties and Pharmacodynamics of Solid Drugs

Volume:24
Yanan Zhou, Jingkang Wang*, Yan Xiao, Ting Wang and Xin Huang

Cocrystal and its Application in the Field of Active Pharmaceutical Ingredients and Food Ingredients

Volume:24
Na Wang, Chuang Xie, Haijiao Lu, Nannan Guo, Yajing Lou, Weiyi Su and Hongxun Hao*

Anti-Cancer and Radio-Sensitizing Effects of Curcumin in Nasopharyngeal Carcinoma

Volume:24
Amir Abbas Momtazi, Faezeh Ghasemi, Amirreza Hesari, Muhammed Majeed, Michele Caraglia and Amirhossein Sahebkar*

Carboxymethyl-hexanoyl Chitosan Nanodroplets for Ultrasonic Imaging and Drug Delivery to Tumor

Volume:24
Yu Jinsui, Situ Bing, Luo Muhua, Li Yue, Liao Jianyi, Du Meng, Cai Kuan, Yang Chaopin, Zhang Hui and Chen Zhiyi*

Immunometabolic Changes in Hepatocytes Arising from Obesity and the Practice of Physical Exercise

Volume:24
Paula Alves Monteiro*, Wagner Prado, Thiago Ricardo dos Santos Tenório, Luciane Magri Tomaz, David H St-Pierre and Fabio Santos Lira

Phase Behavior of Polymorphic Fats in Drug Delivery Systems - A Review of the State of Art

Volume:24
J. R. Campos, A. R. Fernandes, P. Severino, M. L. Garcia, S. B. Souto and E. B. Souto*

One Molecule, Many Targets and Numerous Effects: The Pleiotropy of Curcumin Lies in its Chemical Structure

Volume:24
Mahdi Hatamipour, Thomas P. Johnston and Amirhossein Sahebkar*

Recent Advances in Magnetic Nanoparticle-based Molecular Probes for Hepatocellular Carcinoma Diagnosis and Therapy

Volume:24
Qi Zhang, Sudan Wang, Ruirui Qiao*, Michael Whittaker, John Quinn, Thomas P. Davis and Hongjun Li

Anti-aging and Anti-aggregation Properties of Polyphenolic Compounds in C. elegans

Volume:24
Nikoletta Papaevgeniou and Niki Chondrogianni*

Chitosan-coated C-phycocyanin Liposome for Extending the Neuroprotective Time Window Against Ischemic Brain Stroke

Volume:24
Goo Yong Chung, Kyou Hee Shim, Hye Jin Kim, Seul Ki Min and Hwa Sung Shin*

Role of Oxidative Stress in Diabetic Retinopathy and the Beneficial Effects of Flavonoids

Volume:24
Mohammad Shamsul Ola*, Dalia Al-Dosari and Abdullah S. Alhomida

Similar and Distinct Mechanisms in the Protective Processes of Upper and Lower Gastrointestinal Tract

Volume:24
K. Gyires*, Sz. B. László, B. Lázár and Z. S. Zádori

Defense Mechanisms Against Acid Exposure by Dental Enamel Formation, Saliva and Pancreatic Juice Production

Volume:24
Robert Racz, Akos Nagy, Zoltan Rakonczay , Erika Katalin Dunavari, Gabor Gerber and Gabor Varga*

MALT Lymphoma, Stress Ulcer and Cholinergic Nerves from the Viewpoint of Bilateral and Unilateral Truncal Vagotomy and Substance P

Volume:24
Yosuke Kodama, Kazuki Sasaki, Futa Murasato, Anders Øverby, Shinichi Takahashi, Somay Y Murayama, Hidenori Matsui and Masahiko Nakamura*

Nanocrystal Technology as a Strategy to Improve Drug Bioavailability and Antitumor Efficacy for the Cancer Treatment

Volume:24
Mingxue Fan, Sicong Geng, Yang Liu, Jing Wang, Yiting Wang, Jian Zhong*, Zhiqiang Yan* and Lei Yu

Role of Formyl Peptide Receptors in Gastrointestinal Healing

Volume:24
Nella Prevete, Amato de Paulis, Dolores Sgambato, Rosa Marina Melillo, Giuseppe D’Argenio, Lorenzo Romano, Rocco Maurizio Zagari and Marco Romano*

Soft Biomaterial-based Nanocrystal in Pharmaceutical

Volume:24
Nandi Chen, Taojunfeng Su, Zhe Cheng* and Feifei An*

Nanocrystals: The Preparation, Precise Control, and Application Toward the Pharmaceutics and Foods Industry

Volume:24
Cao Wu, Zhou Chen*, Ya Hu, Zhiyuan Rao, Wangping Wu and Zhaogang Yang

Pharmaceutical Strategies for Stabilizing Drug Nanocrystals

Volume:24
Hyerim Yang, Hyeongmin Kim, Sumin Jung, Hyeyeon Seo, Shofa Khoirun Nida, Seung-Yup Yoo and Jaehwi Lee*

Editorial: Crystallization for Pharmaceutical and Food Science

Volume:24
Hongxun Hao*, Jian Zhong , Qiuxiang Yin and Xichang Wang

Lifestyle and Peptic Ulcer Disease

Volume:24
Berrak C Yegen*

Internal and External Triggering Mechanism of “Smart” Nanoparticle-Based DDSs in Targeted Tumor Therapy

Volume:24
Xian-ling Qiana, Jun Li , Ran Wei, Hui Lin and Li-xia Xiong*

Otilonium Bromide: A Drug with a Complex Mechanism of Action

Volume:24
Stefano Evangelista, Chiara Traini and Maria Giuliana Vannucchi*

Molecular Targets of Phytochemicals for Skin Inflammation

Volume:24
Jong-Eun Kim and Ki Won Lee*

Role of Melatonin in the Inflammatory Process and its Therapeutic Potential

Volume:24
Livia Carrascal, Pedro Nunez-Abades, Antonio Ayala and Mercedes Cano*

N-Acetyl Cysteine and Vitamin D Supplementation in Treatment Resistant Obsessive- Compulsive Disorder Patients: A General Review

Volume:24
Flavia di Michele*, Alberto Siracusano, Alessandra Talamo and Cinzia Niolu

Heterocyclic N-oxides - A Promising Class of Agents against Tuberculosis, Malaria and Neglected Tropical Diseases

Volume:24
Guilherme Felipe dos Santos Fernandes, Aline Renata Pavan and Jean Leandro dos Santos*

Comparative Study of the Effects Exerted by N-Valproyl-L-Phenylalanine and N-valproyl-L-tryptophan on CA1 Hippocampal Epileptiform Activity in Rat

Volume:24
Fabio Carletti*, Valerio Rizzo, Giuditta Gambino, Viviana De Caro, Flavia Maria Sutera, Libero Italo Giannola, Giuseppe Ferraro and Pierangelo Sardo*

The Effects of Coenzyme Q10 Supplementation on Lipid Profiles Among Patients with Metabolic Diseases: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Volume:24
Nasrin Sharifi, Reza Tabrizi, Mahmood Moosazadeh, Naghmeh Mirhosseini, Kamran B Lankarani, Maryam Akbari, Maryam Chamani, Fariba Kolahdooz and Zatollah Asemi*

A Novel Fluorescence-Labeled Curcumin Conjugate: Synthesis, Evaluation and Imaging on Human Cell Lines

Volume:24
Sumbla Sheikh*, Alexander Sturzu , Hubert Kalbacher , Thomas Nagele, Christopher Weidenmaier , Marius Horger, Christian Schwentner , Ulrike Ernemann and Stefan Heckl

Comparative Assay of 2D and 3D Cell Culture Models: Proliferation, Gene Expression and Anticancer Drug Response

Volume:24
Aline G. Souza*, Isaura Beatriz. B. Silva, Esther Campos-Fernandez, Leticia S. Barcelos, Jessica Brito Souza, Karina Marangoni, Luiz R. Goulart and Vivian Alonso-Goulart

Management of Antithrombotic Therapy in Patients with Coronary Artery Disease or Atrial Fibrillation who Underwent Abdominal Surgical Operations

Volume:24
Dimitrios Schizas*, Maria Kariori, Konstantinos Dean Boudoulas, Gerasimos Siasos, Nikolaos Patelis, Charalampos Kalantzis , Moldovan Carmen-Maria and Manolis Vavuranakis

Association Between Drug Burden Index and Functional and Cognitive Function in Patients with Multimorbidity

Volume:24
Angela Mª Villalba-Moreno, Eva Rocio Alfaro-Lara, Aitana Rodriguez-Perez, Daniel Banez-Toro, Susana Sanchez-Fidalgo*, Mª Concepcion Perez-Guerrero, Bernardo Santos-Ramos and Mª Dolores Nieto-Martin

Orthopedic Aspects of the Diabetic Foot

Volume:24
E. J.A. Tijdens-Creusen, Paul C Jutte*, W. M.H.H. Schoumakers, M. M. Van der Klauw and Marjan Wouthuyzen-Bakker

Potential Use of Nanomedicine for the Anti-inflammatory Treatment of Neurodegenerative Diseases

Volume:24
Maria Dolores Cayero-Otero, Ana M. Espinosa-Oliva*, Antonio J. Herrera, Irene Garcia-Dominguez, Mercedes Fernandez-Arevalo, Lucia Martin-Banderas and Rocio M. de Pablos

Virtual Screening Studies for Discovery of Novel Inhibitors of Inflammatory Process Targets

Volume:24
Marcus Tullius Scotti*, Mateus Feitosa Alves, Chonny Alexander Herrera-Acevedo and Luciana Scotti

Signaling Pathways in Inflammation and Anti-inflammatory Therapies

Volume:24
Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*

Cytochrome P450S and Alcoholic Liver Disease

Volume:24
Yongke Lu* and Arthur I. Cederbaum

Advances in the Use of Anti-inflammatory Agents to Manage Chemotherapy-induced Oral and Gastrointestinal Mucositis

Volume:24
Vaishnavi J. Mahendran, Andrea M. Stringer, Susan J. Semple, Yunmei Song and Sanjay Garg*

Recent Findings in Molecular Basis of Inflammation and Anti-inflammatory Plants

Volume:24
Sedigheh Kazemi, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei*

Inflammation and Heart Diseases

Volume:24
Li Yue-Chun*

The Potential Mechanisms of Exercise-induced Cognitive Protection: A Literature Review

Volume:24
Jennifer E. Norman*, Jennifer Rutkowsky, Sue Bodine and John C. Rutledge

Phage-based Nanomedicines as New Immune Therapeutic Agents for Breast Cancer

Volume:24
Atefeh Arab*, Rezvan Yazdian Robati*, Jessica Nicastro, Roderick Slavcev and Javad Behravan

The Role of Inflammation in Neurological Disorders

Volume:24
Diana Degan, Raffaele Ornello, Cindy Tiseo, Antonio Carolei, Simona Sacco and Francesca Pistoia*

Plant-produced Recombinant Influenza A Vaccines Based on the M2e Peptide

Volume:24
Eugenia S. Mardanova and Nikolai V. Ravin*

The Impact of Omega 3 Fatty Acids in Atherosclerosis and Arterial Stiffness: An Overview of their Actions

Volume:24
Alexios Verveniotis, Gerasimos Siasos*, Evangelos Oikonomou, Vasiliki Tsigkou, Nikolaos Papageorgiou, Marina Zaromitidou, Theodora Psaltopoulou, Georgios Marinos, Spyridon Deftereos, Manolis Vavuranakis, Christodoulos Stefanadis, Athanasios G. Papavassiliou and Dimitris Tousoulis

TA-65, A Telomerase Activator improves Cardiovascular Markers in Patients with Metabolic Syndrome

Volume:24
Maria Luz Fernandez*, Minu Sara Thomas, Bruno S. Lemos, Diana M. DiMarco, Amanda Missimer, Melissa Melough, Ock K. Chun, Ana Gabriela Murillo, Hana Alyousef and Isabel Medina-Vera

Natural Snake Venom Inhibitors and their Pharmaceutical Uses: Challenges and Possibilities

Volume:24
Soledad Lorena Saavedra*, Lucia Avila, Silvana Laura Giudicessi, Fernando Albericio, Silvia Andrea Camperi, Osvaldo Cascone and Maria Camila Martinez-Ceron*

Novel Optical Techniques for Imaging Microcirculation in the Diabetic Foot

Volume:24
Onno August Mennes*, J. J. van Netten, R. H.J.A Slart and Wiendelt Steenbergen

New Imaging Tracers for the Infected Diabetic Foot (Nuclear and Optical Imaging)

Volume:24
Alfred O. Ankrah, Hans C. Klein and Philip H. Elsinga*

An Overview on Diabetic foot Infections, including Issues Related to Associated Pain, Hyperglycemia and Limb Ischemia

Volume:24
Ilker Uckay*, Francois R. Jornayvaz, Dan Lebowitz, Giacomo Gastaldi, Karim Gariani and Benjamin A. Lipsky

Diabetic Foot Infection: The Role of PET/CT Imaging

Volume:24
Elite Arnon-Sheleg and Zohar Keidar*

Leukocyte Imaging of the Diabetic Foot

Volume:24
Chiara Lauri, Andor W.J.M. Glaudemans and Alberto Signore*

Synthesis of Novel Derivatives of Quinazoline Schiff base Compound Promotes Epithelial Wound Healing

Volume:24
Elham Bagheri, Kamelia Saremi, Fatemeh Hajiaghaalipour, Fadhil Lafta Faraj, Hapipah Mohd Ali, Mahmood Ameen Abdulla, Si Lay Khaing and Nur’Ain Salehen*

Editorial: The Diabetic Foot

Volume:24
Andor W.J.M. Glaudemans*, Thomas C. Kwee and Riemer H.J.A. Slart

Applications of Polymeric Nanoparticles in Oral Diseases: A Review of Recent Findings

Volume:24
Paula Chaves, Joao Oliveira, Alex Haas and Ruy Carlos Ruver Beck *

Cyclodextrins as Drug Carriers in Pharmaceutical Technology: The State of the Art

Volume:24
Jaime Conceição*, Oluwatomide Adeoye, Helena Maria Cabral-Marques and Jose Manuel Sousa Lobo

Mutations of Nuclear and Mitochondrial Genomes as Potential Targets for the Treatment of Metabolic Syndrome

Volume:24
Elena V. Galitsyn, Andrey V. Zhelankin, Igor A. Sobenin* and Alexander N. Orekhov

Nanodiagnostics and Nanodelivery Applications in Genetic Alterations

Volume:24
Maria Sofia Falzarano, Cristina Flesia, Roberta Cavalli , Caterina Guiot and Alessandra Ferlini*

mazE Antitoxin of Toxin Antitoxin System and fbpA as Reliable Targets to Eradication of Neisseria meningitidis

Volume:24
Abbas Maleki, Sobhan Ghafourian, Iraj Pakzad, Behzad Badakhsh and Nourkhoda Sadeghifard*

Immunotheraphy in Allergic Diseases

Volume:24
Albert Roger, Maria Basagana, Aina Teniente-Serra, Nathalie Depreux, Yanina Jurgens , Clara Padro, Sira Miquel, Carolina Elduque and Eva M Martinez-Caceres*

Targeting lncRNAs for Cardiovascular Therapeutics in Coronary Artery Disease

Volume:24
Dongsheng Yu, Chuanfeng Tang, Peiyu Liu, Weichun Qian* and Liang Sheng*

Adhesive Drug Delivery Systems Based on Polyelectrolyte Complex Nanoparticles (PEC NP) for Bone Healing

Volume:24
Martin Muller*, David Vehlow, Bernhard Torger and Birgit Urban

A Review on Oral Liquid as an Emerging Technology in Controlled Drug Delivery System

Volume:24
Sangmesh Raosaheb Torne, Angappan Sheela* and N C Sarada