Current Pharmaceutical Design

William A. Banks  
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Editor's Choice

Neuroprotection in Hypoxic-Ischemic Brain Injury Targeting Glial Cells

Volume: 23   Issue: 26
Pp: 3899-3906
Sofia Mucci, Maria Ines Herrera, George E. Barreto, Rodolfo Kolliker-Frers and Francisco Capani
DOI: 10.2174/1381612823666170727145422

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Recent Advances on the Role of microRNAs in both Insulin Resistance and Cancer

Volume: 23   Issue: 25
Pp: 3658-3666
Adele Vivacqua, Paola De Marco, Antonino Belfiore and Marcello Maggiolini
DOI: 10.2174/1381612823666170622105123

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Gene Delivery with Organic Electronic Biomaterials

Volume: 23   Issue: 24
Pp: 3614-3625
Kathryn F.A. Clancy and John G. Hardy
DOI: 10.2174/1381612823666170710124137

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Polyamine Transport and Synthesis in Trichomonas vaginalis: Potential Therapeutic Targets

Volume: 23   Issue: 23
Pp: 3359-3366
Maria Elizbeth Alvarez-Sanchez, Jose Luis Villalpando, Laura Itzel Quintas-Granados and Rossana Arroyo
DOI: 10.2174/1381612823666170703162754

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Gut Microbiota: A New Marker of Cardiovascular Disease

Volume: 23   Issue: 22
Pp: 3233-3238
Antonio Garcia-Rios, Jose David Torres-Peña, Francisco Perez-Jimenez and Pablo Perez-Martinez
DOI: 10.2174/1381612823666170317144853

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miR-126 as a Therapeutic Agent for Diabetes Mellitus

Volume: 23   Issue: 22
Pp: 3309-3314
Elham Pishavar and Javad Behravan
DOI: 10.2174/1381612823666170424120121

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BDNF/NF-κB Signaling in the Neurobiology of Depression

Volume: 23   Issue: 21
Pp: 3154-3163
Ariel Caviedes, Carlos Lafourcade, Claudio Soto and Ursula Wyneken
DOI: 10.2174/1381612823666170111141915

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Surface Engineered Dendrimers in siRNA Delivery and Gene Silencing

Volume: 23   Issue: 20
Pp: 2952-2975
Vishakha Tambe, Shreya Thakkar, Nidhi Raval, Dilip Sharma, Kiran Kalia and Rakesh K. Tekade
DOI: 10.2174/1381612823666170314104619

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Food as Pharma? The Case of Glucosinolates

Volume: 23   Issue: 19
Pp: 2697-2721
Edoardo Capuano, Matthijs Dekker, Ruud Verkerk and Teresa Oliviero
DOI: 10.2174/1381612823666170120160832

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Cytokines Induced During Influenza Virus Infection

Volume: 23   Issue: 18
Pp: 2616-2622
Tatiana Betakova, Anna Kostrabova, Veronika Lachova and Lucia Turianova
DOI: 10.2174/1381612823666170316123736

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Curcumin and Endothelial Function: Evidence and Mechanisms of Protective Effects

Volume: 23   Issue: 17
Pp: 2462-2473
Maryam S. Karimian, Matteo Pirro, Thomas P. Johnston, Muhammed Majeed and Amirhossein Sahebkar
DOI: 10.2174/1381612823666170222122822

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Gut Microbiota Modulation and Anti-Inflammatory Properties of Dietary Polyphenols in IBD: New and Consolidated Perspectives

Volume: 23   Issue: 16
Pp: 2344-2351
Angelo Santino, Aurelia Scarano, Stefania De Santis, Maria De Benedictis, Giovanna Giovinazzo and Marcello Chieppa
DOI: 10.2174/1381612823666170207145420

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Traumatic Brain Injury: Preclinical Imaging Diagnostic(s) and Therapeutic Approaches

Volume: 23   Issue: 13
Pp: 1909-1915
Eric L. Kaijzel, Ermond R. van Beek, Marieke A. Stammes, Ivo Que, Alan B. Chan, Clemens W.G.M. Lowik and Luis J. Cruz
DOI: 10.2174/1381612823666170116141116

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Targeting Obesity for the Prevention of Chronic Cardiovascular Disease Through Gut Microbiota-Herb Interactions: An Opportunity for Traditional Herbs

Volume: 23   Issue: 8
Pp: 1142-1152
Feng Chen, Jun Jiang, Dan-Dan Tian, Qi Wen, Yong-Hui Li, Jun-Qing Zhang, Chen Cheng and Tengfei Wang
DOI: 10.2174/1381612822666161014115724

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The Role of Biologically Active Ingredients from Chinese Herbal Medicines in the Regulation of Autophagy in Treating Cardiovascular Diseases and Other Chronic Diseases

Volume: 23   Issue: 7
Pp: 1060-1069
Jie Li, Yonghong Gao, Xiaomeng Ren, Yanda Li, Lijun Wu, Xinyu Yang, Jie Wang, Hongcai Shang, Xingjiang Xiong and Yanwei Xing
DOI: 10.2174/1381612822666161021161850

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PPAR Agonists, Atherogenic Dyslipidemia and Cardiovascular Risk

Volume: 23   Issue: 6
Pp: 894-902
Dragana Nikolic, Giuseppa Castellino, Maciej Banach, Peter P. Toth, Ekaterina Ivanova, Alexander N. Orekhov, Giuseppe Montalto and Manfredi Rizzo
DOI: 10.2174/1381612822666161006151134

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miRNAs: New Biomarkers and Therapeutic Targets in Dementia

Volume: 23   Issue: 5
Pp: 669-692
Ana Teresa de Barros Viegas, Joana Ribeiro Guedes, Ana Rafaela Oliveira, Ana Maria Sequeira Cardoso and Ana Luisa Colaco Cardoso
DOI: 10.2174/1381612823666170111094702

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Glaucoma: Hot Topics in Pharmacology

Volume: 23   Issue: 4
Pp: 596-607
Shiama I. Balendra, Parth Arvind Shah, Mishank Jain, Andrzej Grzybowski and Maria F. Cordeiro
DOI: 10.2174/1381612822666161129151308

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Predictive Biomarkers for Linking Disease Pathology and Drug Effect

Volume: 23   Issue: 1
Pp: 29-54
Bernd Mayer, Andreas Heinzel, Arno Lukas and Paul Perco
DOI: 10.2174/1381612822666161006153639

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Perivascular adipose tissue as an endocrine organ: the role of statins

Volume: 23   Issue:
Pp: 1-1
Fabio Sanna, Marios Margaritis and Charalambos Antoniades
DOI: 10.2174/1381612823666170926133843

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Genetic Predictors of Drug Hypersensitivity

Volume: 22   Issue: 45
Pp: 6725-6733
Jose A. Cornejo-Garcia, Abderrahim Oussalah, Miguel Blanca, Rosa-Maria Gueant-Rodriguez, Cristobalina Mayorga, Julie Waton, Annick Barbaud, Francesco Gaeta, Antonino Romano and Jean-Louis Gueant
DOI: 10.2174/1381612822666160927114941

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Unraveling Antibody Display: Systems Biology and Personalized Medicine

Volume: 22   Issue: 43
Pp: 6560-6576
Luiz Ricardo Goulart, Paula Souza Santos, Ana Paula Carneiro, Barbara Brasil Santana, Antonio C. Vallinoto and Thaise Goncalves Araujo
DOI: 10.2174/1381612822666160923112816

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The Gut-Brain Axis, Including the Microbiome, Leaky Gut and Bacterial Translocation: Mechanisms and Pathophysiological Role in Alzheimer’s Disease

Volume: 22   Issue: 40
Pp: 6152-6166
Cristiano A. Köhler, Michael Maes, Anastasiya Slyepchenko, Michael Berk, Marco Solmi, Krista L. Lanctôt and André F. Carvalho
DOI: 10.2174/1381612822666160907093807

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Targeted Nanosystems to Prostate Cancer

Volume: 22   Issue: 39
Pp: 5962-5975
Luiz Cláudio Rodrigues Pereira da Silva, Flávia Almada do Carmoa, Luiz Eurico Nasciutti, Patrícia Zancan, Plínio Cunha Sathler and Lucio Mendes Cabral
DOI: 10.2174/1381612822666160715131359

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Cardiovascular Prevention in Obese Patients

Volume: 22   Issue: 37
Pp: 5687-5697
Manuel F. Landecho, Rafael Moncada, Víctor Valentí and Gema Fruhbeck
DOI: 10.2174/1381612822666160822125834

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Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers

Volume: 22   Issue: 34
Pp: 5257-5269
Hamid Reza Mirzaei, Amirhossein Sahebkar, Mohsen Mohammadi, Reza Yari, Hossein Salehi, Mohammad Hasan Jafari, Afshin Namdar, Ehsan Khabazian, Mahmoud Reza Jaafari and Hamed Mirzaei
DOI: 10.2174/1381612822666160303110838

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Experimental-Theoretic Approach to Drug-Lymphocyte Interactome Networks with Flow Cytometry and Spectral Moments Perturbation Theory

Volume: 22   Issue: 33
Pp: 5114-5119
Esvieta Tenorio-Borroto, Fabiola Rivera Ramírez, Juan Carlos Vazquez Chagoyan, Roberto Montes de Oca Jimenez, Xerardo Garcia-Mera and Humberto Gonzalez-Diaz
DOI: 10.2174/1381612822666160805164308

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Statins in Stroke Prevention: Present and Future

Volume: 22   Issue: 30
Pp: 4638-4644
Luis Castilla-Guerra, María del Carmen Fernandez-Moreno and Miguel Angel Colmenero-Camacho
DOI: 10.2174/1381612822666160510125229

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Antiplatelet Therapy in Acute Coronary Syndromes. Evidence Based Medicine

Volume: 22   Issue: 29
Pp: 4519-4536
Evangelos Oikonomou, Georgia Vogiatzi, Georgios-Angelos Papamikroulis, Leon Naar, Gerasimos Siasos, Konstantinos Mourouzis, Theodoros Zografos, Manolis Vavuranakis, Alexis Antonopoulos and Dimitris Tousoulis
DOI: 10.2174/1381612822666160617105634

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Modulation of Energy Intake and Expenditure Due to Habitual Physical Exercise

Volume: 22   Issue: 24
Pp: 3681-3699
Matoulek Martin, Slaby Krystof, Radvansky jiri, Dankova Martina, Vetrovska Renata, Mikes Ondrej, Svacina Stepan and Tuka Vladimir
DOI: 10.2174/1381612822666160419144200

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Modelling DNA Repair Pathways: Recent Advances and Future Directions

Volume: 22   Issue: 23
Pp: 3527-3546
Francesco Gentile, Jack A. Tuszynski and Khaled H. Barakat
DOI: 10.2174/1381612822666160420141435

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Natural Polymeric Nanoparticles for Brain-Targeting: Implications on Drug and Gene Delivery

Volume: 22   Issue: 22
Pp: 3305-3323
Ahmed O. Elzoghby, Mahmoud M. Abd-Elwakil, Kholod Abd-Elsalam, Mustafa T. Elsayed, Yosra Hashem and Ola Mohamed
DOI: 10.2174/1381612822666160204120829

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Association of Oxidative Stress with Psychiatric Disorders

Volume: 22   Issue: 20
Pp: 2960-2974
Waseem Hassan, Hamsa Noreen, Vitor Castro-Gomes, Imdadullah Mohammadzai, Joao Batista Teixeira da Rocha and J. Landeira-Fernandez
DOI: 10.2174/1381612822666160307145931

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An Update on Natural Products with Carbonic Anhydrase Inhibitory Activity

Volume: 22   Issue: 12
Pp: 1570-1591
Anastasia Karioti, Fabrizio Carta and Claudiu T. Supuran
DOI: 10.2174/1381612822666151211094235

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Albumin-Based Nanodevices as Drug Carriers

Volume: 22   Issue: 10
Pp: 1371-1390
Ana Loureiro, Nuno G. Azoia, Andreia C. Gomes and Artur Cavaco-Paulo
DOI: 10.2174/1381612822666160125114900

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Can Probiotics Cure Inflammatory Bowel Diseases?

Volume: 22   Issue: 7
Pp: 904-917
Siva Kumar Korada, Nagendra sastry Yarla, Anupam Bishayee, Gjumrakch Aliev, Aruna Lakshmi K., Arunasree M.K., Dhananjaya B.L. and Vijendra Mishra
DOI: 10.2174/1381612822666151209153249

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Cadherins: The Superfamily Critically Involved in Breast Cancer

Volume: 22   Issue: 5
Pp: 616-638
Maeirah Afzal Ashaie and Ezharul Hoque Chowdhury
DOI: 10.2174/138161282205160127095338

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The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatment

Volume: 22   Issue: 3
Pp: 397-403
Sharareh Gholamin, Alireza Pasdar, Mohammad Sadegh Khorrami, Hamed Mirzaei, Hamid Reza Mirzaei, Rasoul Salehi, Gordon A. Ferns, Majid Ghayour-Mobarhan and Amir Avan
DOI: 10.2174/1381612822666151112151924

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Oxidative stress and Parkinson’s disease: New hopes in treatment with herbal antioxidants

Volume: 22   Issue: 2
Pp: 238-246
Amir Sarrafchi, Mahmoud Bahmani, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei
DOI: 10.2174/1381612822666151112151653

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Cross-Talk Between Adipose Tissue Health, Myocardial Metabolism and Vascular Function: The Adipose-Myocardial and Adipose-Vascular Axes promotion: free to download

Volume: 22   Issue: 1
Pp: 59-67
Patricia Iozzo and Maria Angela Guzzardi
DOI: 10.2174/1381612822666151109111834

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Controlled Release Inhalable Polymeric Microspheres for Treatment of Pulmonary Arterial Hypertension

Volume: 21   Issue: 40
Pp: 5868-5876
Aparna Saigal, Wai Kiong Ng, Reginald B.H. Tan and Sui Yung Chan
DOI: 10.2174/1381612821666151008124451

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New Approaches With Natural Product Drugs for Overcoming Multidrug Resistance in Cancer

Volume: 21   Issue: 38
Pp: 5589-5604
Jelena Dinic, Ana Podolski-Renic, Tijana Stankovic, Jasna Bankovic and Milica Pesic
DOI: 10.2174/1381612821666151002113546

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Cyclodextrin-Based Delivery Systems for Arthritic Diseases: From Development to Experimental Therapeutics

Volume: 21   Issue: 33
Pp: 4907-4916
Monica Helena Monteiro Nascimento, Alessandra Cristina Santos Akkari, Kelly Cristina Freitas Mariano, Antonio Sergio Kimus Braz, Christiane Bertachini Lombello and Daniele Ribeiro de Araujo
DOI: 10.2174/1381612821666150820104427

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Brain Targeting of siRNA via Intranasal Pathway

Volume: 21   Issue: 31
Pp: 4606-4613
Chandana Mohanty, Paromita Kundu and Sanjeeb K. Sahoo
DOI: 10.2174/138161282131151013191737

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Antisense Therapy for Cardiovascular Diseases

Volume: 21   Issue: 30
Pp: 4417-4426
M. Ian Phillips, Jessica Costales, Robert J. Lee, Edilamar Oliveira and Andrew B. Burns
DOI: 10.2174/1381612821666150803150402

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Stimuli-Responsive Nanoparticles for siRNA Delivery

Volume: 21   Issue: 29
Pp: 4131-4144
Josimar O. Eloy, Raquel Petrilli, Renata F. V. Lopez and Robert J. Lee
DOI: 10.2174/1381612821666150901095349

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Atrial Fibrillation and Gastro-Oesophageal Reflux Disease - Controversies and Challenges

Volume: 21   Issue: 26
Pp: 3829-3834
Mariana Floria, Oana Barboi, Ciprian Rezus, Valentin Ambarus, Cristina Cijevschi-Prelipcean, Gheorghe Balan and Vasile Liviu Drug
DOI: 10.2174/1381612821666150319100003

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The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy

Volume: 21   Issue: 25
Pp: 3582-3588
Zofia Blach-Olszewska, Ewa Zaczynska, Kasia Gustaw-Rothenberg, Marco Avila-Rodrigues, George E. Barreto, Jerzy Leszek and Gjumrakch Aliev
DOI: 10.2174/1381612821666150710144829

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Multifunctional Delivery Systems for Advanced oral Uptake of Peptide/Protein Drugs

Volume: 21   Issue: 22
Pp: 3097-3110
Jin Woo Park, Sun Jin Kim, Dong Sup Kwag, Sol Kim, Jeyoung Park, Yu Seok Youn, You Han Bae and Eun Seong Lee
DOI: 10.2174/1381612821666150531163944

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The Regulation of miRNAs in Inflammation-Related Carcinogenesis

Volume: 21   Issue: 21
Pp: 3023-3031
Yiming Ma, Wenxiao Han, Lan Yang, Longmei He and Hongying Wang
DOI: 10.2174/1381612821666150514105606

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Potential of Peptide-Based Enhancers for Transdermal Delivery

Volume: 21   Issue: 20
Pp: 2814-2822
Luciana B. Lopes, Vanessa F.M. Carvalho and Debora P. de Lemos
DOI: 10.2174/1381612821666150428143243

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Characterization of Particulate Drug Delivery Systems for Oral Delivery of Peptide and Protein Drugs

Volume: 21   Issue: 19
Pp: 2611-2628
Philip Carsten Christophersen, Mathias Fano, Lasse Saaby, Mingshi Yang, Hanne Mørck Nielsen and Huiling Mu
DOI: 10.2174/1381612821666150416100943

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Molecular Imaging and Targeted Drug Delivery Using Albumin-Based Nanoparticles

Volume: 21   Issue: 14
Pp: 1889-1898
Ji Young Yhee, Jangwook Lee, Hyeyoun Chang, Jeewon Lee, Ick Chan Kwon and Kwangmeyung Kim
DOI: 10.2174/1381612821666150302115809

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