Current Gene Therapy

Ignacio Anegon
Director INSERM UMR 1064-Center for Research in Transplantation and Immunology
CHU de Nantes. 30, boulevard
Nantes
France

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Most Cited Article

Targeted Genome Editing Tools for Disease Modeling and Gene Therapy promotion: free to download

Volume:14   Issue:1
Pp: 2-9
Mi Cai and Yi Yang
DOI: 10.2174/156652321402140318165450

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Preclinical Evaluation of Efficacy and Safety of an Improved Lentiviral Vector for the Treatment of β-Thalassemia and Sickle Cell Disease open access plus

Volume:15   Issue:1
Pp: 64-81
Olivier Negre, Cynthia Bartholomae, Yves Beuzard, Marina Cavazzana, Lauryn Christiansen, Celine Courne, Annette Deichmann, Maria Denaro, Edouard de Dreuzy, Mitchell Finer, Raffaele Fronza, Beatrix Gillet-Legrand, Christophe Joubert, Robert Kutner, Philippe Leboulch, Leila Maouche, Anais Paulard, Francis J. Pierciey, Michael Rothe, Byoung Ryu, Manfred Schmidt, Christof von Kalle, Emmanuel Payen and Gabor Veres
DOI: 10.2174/1566523214666141127095336

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Exosomes: A Role for Naturally Occurring Nanovesicles in Cancer Growth, Diagnosis and Treatment

Volume:15   Issue:2
Pp: 182-192
Akhil Srivastava, Justyna Filant, Katherine M. Moxley, Anil Sood, Scott McMeekin and Rajagopal Ramesh
DOI: 10.2174/1566523214666141224100612

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Clinical Immunotherapy of B-Cell Malignancy Using CD19-Targeted CAR T-Cells promotion: free to download

Volume:14   Issue:1
Pp: 35-43
John Maher
DOI: 10.2174/1566523213666131223130554

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TALEN-Mediated Generation and Genetic Correction of Disease-Specific Human Induced Pluripotent Stem Cells

Volume:14   Issue:6
Pp: 461-472
Sivaprakash Ramalingam, Narayana Annaluru, Karthikeyan Kandavelou and Srinivasan Chandrasegaran
DOI: 10.2174/1566523214666140918101725

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Genetically Redirected T Lymphocytes for Adoptive Immunotherapy of Solid Tumors promotion: free to download

Volume:14   Issue:1
Pp: 52-62
Valeria Leuci, Giulia Mesiano, Loretta Gammaitoni, Massimo Aglietta and Dario Sangiolo
DOI: 10.2174/1566523213666131223130353

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A Hantavirus Pulmonary Syndrome (HPS) DNA Vaccine Delivered Using a Spring-powered Jet Injector Elicits a Potent Neutralizing Antibody Response in Rabbits and Nonhuman Primates open access plus

Volume:14   Issue:3
Pp: 200-210
Steve Kwilas, Jennifer M. Kishimori, Matthew Josleyn, Kurt Jerke, John Ballantyne, Michael Royals and Jay W. Hooper
DOI: 10.2174/1566523214666140522122633

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Endoglin Silencing has Significant Antitumor Effect on Murine Mammary Adenocarcinoma Mediated by Vascular Targeted Effect

Volume:15   Issue:3
Pp: 228-244
Tanja Dolinsek, Bostjan Markelc, Masa Bosnjak, Tanja Blagus, Lara Prosen, Simona Kranjc, Monika Stimac, Ursa Lampreht, Gregor Sersa and Maja Cemazar
DOI: 10.2174/1566523215666150126115501

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Integrase-Deficient Lentivirus: Opportunities and Challenges for Human Gene Therapy

Volume:14   Issue:5
Pp: 352-364
Kuan-Can Liu, Bao-Shun Lin, An-Ding Gao, Hong-Yu Ma, Meng Zhao, Rui Zhang, Hui-Hui Yan, Xun-Fei Yi, Si-Jie Lin, Jian-Wen Que and Xiao-Peng Lan
DOI: 10.2174/1566523214666140825124311

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Controlled Gene Delivery Can Enhance Therapeutic Outcome for Cancer Immune Therapy for Melanoma

Volume:15   Issue:1
Pp: 32-43
Shawna A. Shirley, Cathryn G. Lundberg, Fanying Li, Niculina Burcus and Richard Heller
DOI: 10.2174/1566523214666141121111630

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Dual Receptor-Specific Peptides Modified Liposomes as VEGF siRNA Vector for Tumor-Targeting Therapy

Volume:14   Issue:4
Pp: 289-299
Zhenzhen Yang, Bai Xiang, Dawen Dong, Zhanzhang Wang, Jingquan Li and Xianrong Qi
DOI: 10.2174/1566523214666140612151726

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Basic Biology of Adeno-Associated Virus (AAV) Vectors Used in Gene Therapy

Volume:14   Issue:2
Pp: 86-100
Balaji Balakrishnan and Giridhara R. Jayandharan
DOI: 10.2174/1566523214666140302193709

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Symptomatic Improvement, Increased Life-Span and Sustained Cell Homing in Amyotrophic Lateral Sclerosis After Transplantation of Human Umbilical Cord Blood Cells Genetically Modified with Adeno-Viral Vectors Expressing a Neuro-Protective Factor and a Neural Cell Adhesion Molecule

Volume:15   Issue:3
Pp: 266-276
Rustem Robertovich Islamov, Albert Anatolyevich Rizvanov, Marat Alexandrovich Mukhamedyarov, Ilnur Ildusovich Salafutdinov, Ekaterina Evgenevna Garanina, Valeria Yuryevna Fedotova, Valeria Vladimirovna Solovyeva, Yana Olegovna Mukhamedshina, Zufar Zufarovich Safiullov, Andrey Alexandrovich Izmailov, Daria Sergeevna Guseva, Andrey Lvovich Zefirov, Andrey Pavlovich Kiyasov and Andras Palotas
DOI: 10.2174/1566523215666150126122317

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Single-Stranded γPNAs for In Vivo Site-Specific Genome Editing via Watson-Crick Recognition

Volume:14   Issue:5
Pp: 331-342
Raman Bahal, Elias Quijano, Nicole A. McNeer, Yanfeng Liu, Dinesh C. Bhunia, Francesco Lopez-Giraldez, Rachel J. Fields, William M. Saltzman, Danith H. Ly and Peter M. Glazer
DOI: 10.2174/1566523214666140825154158

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Current Genome Editing Tools in Gene Therapy: New Approaches to Treat Cancer

Volume:15   Issue:5
Pp: 511-529
Oleg Shuvalov, Alexey Petukhov, Alexandra Daks, Olga Fedorova, Alexander Ermakov, Gerry Melino and Nickolai A Barlev
DOI: 10.2174/1566523215666150818110241

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Gene Therapy for Chronic Granulomatous Disease: Current Status and Future Perspectives

Volume:14   Issue:6
Pp: 447-460
Kerstin B. Kaufmann, Maria Chiriaco, Ulrich Siler, Andrea Finocchi, Janine Reichenbach, Stefan Stein and Manuel Grez
DOI: 10.2174/1566523214666140918113201

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Adult Stem Cells and Skeletal Muscle Regeneration

Volume:15   Issue:4
Pp: 348-363
Domiziana Costamagna, Emanuele Berardi, Gabriele Ceccarelli and Maurilio Sampaolesi
DOI: 10.2174/1566523215666150630121024

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Tau Silencing by siRNA in the P301S Mouse Model of Tauopathy

Volume:14   Issue:5
Pp: 343-351
Hong Xu, Thomas W. Rosler, Thomas Carlsson, Anderson de Andrade, Ondrej Fiala, Matthias Hollerhage, Wolfgang H. Oertel, Michel Goedert, Achim Aigner and Gunter U. Hoglinger
DOI: 10.2174/156652321405140926160602

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Codon Swapping of Zinc Finger Nucleases Confers Expression in Primary Cells and In Vivo from a Single Lentiviral Vector

Volume:14   Issue:5
Pp: 365-376
Cecilia Abarrategui-Pontes, Alison Creneguy, Reynald Thinard, Eli J. Fine, Virginie Thepenier, Laure Fournier Le Ray, Thomas J. Cradick, Gang Bao, Laurent Tesson, Guillaume Podevin, Ignacio Anegon and Tuan Huy Nguyen
DOI: 10.2174/156652321405140926161748

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Pluripotent Stem Cells for Gene Therapy of Degenerative Muscle Diseases

Volume:15   Issue:4
Pp: 364-380
Mariana Loperfido, Heather B. Steele-Stallard, Francesco Saverio Tedesco and Thierry VandenDriessche
DOI: 10.2174/1566523215666150630121207

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Lentiviral-Mediated Gene Therapy in Fanconi Anemia-A Mice Reveals Long-Term Engraftment and Continuous Turnover of Corrected HSCs

Volume:15   Issue:6
Pp: 550-562
F. Javier Molina-Estevez, Ali Nowrouzi, MLuz Lozano, Anne Galy, Sabine Charrier, Christof von Kalle, Guillermo Guenechea, Juan A. Bueren and Manfred Schmidt
DOI: 10.2174/1566523215666150929110903

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CFTR Inactivation by Lentiviral Vector-mediated RNA Interference and CRISPR-Cas9 Genome Editing in Human Airway Epithelial Cells

Volume:15   Issue:5
Pp: 447-459
Jessica Bellec, Marc Bacchetta, Davide Losa, Ignacio Anegon, Marc Chanson and Tuan Huy Nguyen
DOI: 10.2174/1566523215666150812115939

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EMT Blockage Strategies: Targeting Akt Dependent Mechanisms for Breast Cancer Metastatic Behaviour Modulation

Volume:15   Issue:3
Pp: 300-312
D. Rafael, S. Doktorovova, H.F. Florindo, P. Gener, I. Abasolo, S.Jr. Schwartz and M.A. Videira
DOI: 10.2174/1566523215666150126123642

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Adeno-Associated Virus (AAV) Mediated Dystrophin Gene Transfer Studies and Exon Skipping Strategies for Duchenne Muscular Dystrophy (DMD)

Volume:15   Issue:4
Pp: 395-415
Klaudia Kawecka, Michael Theodoulides, Yalin Hasoglu, Susan Jarmin, Hanna Kymalainen, Anita Le-Heron, Linda Popplewell, Alberto Malerba, George Dickson and Takis Athanasopoulos
DOI: 10.2174/1566523215666150710123830

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Transfection of CXCR-4 Using Microbubble-Mediated Ultrasound Irradiation and Liposomes Improves the Migratory Ability of Bone Marrow Stromal Cells

Volume:15   Issue:1
Pp: 21-31
Gong Wang, Zhongxiong Zhuo, Qian Zhang, Yali Xu, Shengzheng Wu, Lu Li, Hongmei Xia and Yunhua Gao
DOI: 10.2174/1566523214666141121111220

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Foxf1 siRNA Delivery to Hepatic Stellate Cells by DBTC Lipoplex Formulations Ameliorates Fibrosis in Livers of Bile Duct Ligated Mice

Volume:15   Issue:3
Pp: 215-227
Kerstin Abshagen, Malte Brensel, Berit Genz, Kira Roth, Maria Thomas, Volker Fehring, Ute Schaeper and Brigitte Vollmar
DOI: 10.2174/1566523215666150126114634

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The Sleeping Beauty Transposon Vector System for Treatment of Rare Genetic Diseases: An Unrealized Hope?

Volume:15   Issue:3
Pp: 255-265
Philip Boehme, Johannes Doerner, Manish Solanki, Liu Jing, Wenli Zhang and Anja Ehrhardt
DOI: 10.2174/1566523215666150126121353

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Modulation of Notch Signaling as a Therapeutic Approach for Liver Cancer

Volume:15   Issue:2
Pp: 171-181
Guang Wu, George Wilson, Jacob George and Liang Qiao
DOI: 10.2174/1566523214666141224100319

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Gene Electrotransfer: A Mechanistic Perspective open access plus

Volume:16   Issue:2
Pp: 98-129
Christelle Rosazza, Sasa Haberl Meglic, Andreas Zumbusch, Marie-Pierre Rols and Damijan Miklavcic
DOI: 10.2174/1566523216666160331130040

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