Current Gene Therapy


Liang Cheng
College of Bioinformatics Science and Technology
Harbin Medical University
Harbin, Heilongjiang


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Foxf1 siRNA Delivery to Hepatic Stellate Cells by DBTC Lipoplex Formulations Ameliorates Fibrosis in Livers of Bile Duct Ligated Mice

Volume:15   Issue: 3
Pp: 215-227
Kerstin Abshagen, Malte Brensel, Berit Genz, Kira Roth, Maria Thomas, Volker Fehring, Ute Schaeper and Brigitte Vollmar
DOI: 10.2174/1566523215666150126114634

Endoglin Silencing has Significant Antitumor Effect on Murine Mammary Adenocarcinoma Mediated by Vascular Targeted Effect

Volume:15   Issue: 3
Pp: 228-244
Tanja Dolinsek, Bostjan Markelc, Masa Bosnjak, Tanja Blagus, Lara Prosen, Simona Kranjc, Monika Stimac, Ursa Lampreht, Gregor Sersa and Maja Cemazar
DOI: 10.2174/1566523215666150126115501

RETRACTED: Novel and safer self-inactivating vectors for gene therapy of Wiskott-Aldrich Syndrome promotion: free to download

Volume:15   Issue: 3
Pp: 245-254
Emanuele G. Coci, Tobias Maetzig, Daniela Zychlinski, Michael Rothe, Julia D. Suerth, Christoph Klein and Axel Schambach
DOI: 10.2174/1566523215666150126120327

The Sleeping Beauty Transposon Vector System for Treatment of Rare Genetic Diseases: An Unrealized Hope?

Volume:15   Issue: 3
Pp: 255-265
Philip Boehme, Johannes Doerner, Manish Solanki, Liu Jing, Wenli Zhang and Anja Ehrhardt
DOI: 10.2174/1566523215666150126121353

Symptomatic Improvement, Increased Life-Span and Sustained Cell Homing in Amyotrophic Lateral Sclerosis After Transplantation of Human Umbilical Cord Blood Cells Genetically Modified with Adeno-Viral Vectors Expressing a Neuro-Protective Factor and a Neural Cell Adhesion Molecule

Volume:15   Issue: 3
Pp: 266-276
Rustem Robertovich Islamov, Albert Anatolyevich Rizvanov, Marat Alexandrovich Mukhamedyarov, Ilnur Ildusovich Salafutdinov, Ekaterina Evgenevna Garanina, Valeria Yuryevna Fedotova, Valeria Vladimirovna Solovyeva, Yana Olegovna Mukhamedshina, Zufar Zufarovich Safiullov, Andrey Alexandrovich Izmailov, Daria Sergeevna Guseva, Andrey Lvovich Zefirov, Andrey Pavlovich Kiyasov and Andras Palotas
DOI: 10.2174/1566523215666150126122317

In Vivo Bacterial Imaging without Engineering; A Novel Probe-Based Strategy Facilitated by Endogenous Nitroreductase Enzymes

Volume:15   Issue: 3
Pp: 277-288
Michael Stanton, Michelle Cronin, Panos Lehouritis and Mark Tangney
DOI: 10.2174/1566523215666150126122712

EMT Blockage Strategies: Targeting Akt Dependent Mechanisms for Breast Cancer Metastatic Behaviour Modulation

Volume:15   Issue: 3
Pp: 300-312
D. Rafael, S. Doktorovova, H.F. Florindo, P. Gener, I. Abasolo, S.Jr. Schwartz and M.A. Videira
DOI: 10.2174/1566523215666150126123642

Prolyl Hydroxylase Domain-2 Silencing Induced by Hydrodynamic Limb Vein Injection Enhances Vascular Regeneration in Critical Limb Ischemia Mice through Activation of Multiple Genes

Volume:15   Issue: 3
Pp: 313-325
Shourong Wu, Jing Zhang, Can Huang, Huizhen Jia, Yunxia Wang, Zhiling Xu, Li Yang, Makoto Miyagishi and Vivi Kasim
DOI: 10.2174/156652321503150329003735