Current Gene Therapy


Liang Cheng
College of Bioinformatics Science and Technology
Harbin Medical University
Harbin, Heilongjiang


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Single-Stranded γPNAs for In Vivo Site-Specific Genome Editing via Watson-Crick Recognition

Volume:14   Issue: 5
Pp: 331-342
Raman Bahal, Elias Quijano, Nicole A. McNeer, Yanfeng Liu, Dinesh C. Bhunia, Francesco Lopez-Giraldez, Rachel J. Fields, William M. Saltzman, Danith H. Ly and Peter M. Glazer
DOI: 10.2174/1566523214666140825154158

Tau Silencing by siRNA in the P301S Mouse Model of Tauopathy

Volume:14   Issue: 5
Pp: 343-351
Hong Xu, Thomas W. Rosler, Thomas Carlsson, Anderson de Andrade, Ondrej Fiala, Matthias Hollerhage, Wolfgang H. Oertel, Michel Goedert, Achim Aigner and Gunter U. Hoglinger
DOI: 10.2174/156652321405140926160602

Integrase-Deficient Lentivirus: Opportunities and Challenges for Human Gene Therapy

Volume:14   Issue: 5
Pp: 352-364
Kuan-Can Liu, Bao-Shun Lin, An-Ding Gao, Hong-Yu Ma, Meng Zhao, Rui Zhang, Hui-Hui Yan, Xun-Fei Yi, Si-Jie Lin, Jian-Wen Que and Xiao-Peng Lan
DOI: 10.2174/1566523214666140825124311

Codon Swapping of Zinc Finger Nucleases Confers Expression in Primary Cells and In Vivo from a Single Lentiviral Vector

Volume:14   Issue: 5
Pp: 365-376
Cecilia Abarrategui-Pontes, Alison Creneguy, Reynald Thinard, Eli J. Fine, Virginie Thepenier, Laure Fournier Le Ray, Thomas J. Cradick, Gang Bao, Laurent Tesson, Guillaume Podevin, Ignacio Anegon and Tuan Huy Nguyen
DOI: 10.2174/156652321405140926161748

Reversal of Bone Cancer Pain by HSV-1-Mediated Silencing of CNTF in an Afferent Area of the Spinal Cord Associated with AKT-ERK Signal Inhibition

Volume:14   Issue: 5
Pp: 377-388
Xu Yang, Jia Liu, Zun-Jing Liu, Qing-Jie Xia, Mu He, Ran Liu, Wei Liu, Wei Wang, Jin Liu, Xin-Fu Zhou, Yun-Hui Zhang and Ting-Hua Wang
DOI: 10.2174/156652321405140926162236

Identification of Vβ7.1_H3F7 as a Therapeutic Gene Encoding TCR Specific to Hepatocellular Carcinoma

Volume:14   Issue: 5
Pp: 389-399
Shulin Huang, Han Shen, Zhiming Li, Sung-Kay Chiu, Runsheng Ruan, Lanfeng Xiao and Chi-Meng Tzeng
DOI: 10.2174/1566523214666140825124733

SALL4: Engine of Cell Stemness

Volume:14   Issue: 5
Pp: 400-411
Jianhua Xiong
DOI: 10.2174/1566523214666140825125138