Current Medicinal Chemistry

This journal supports open access

Editor-in-Chief:

Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

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Abstract Ahead of Print

Metal Complexes As Promising Agents For Biomedical Applications

Volume:26
Natalia V. Loginova*, Hleb I. Harbatsevich, Nikolai P. Osipovich, Galina A. Ksendzova, Tatsiana V. Koval’chuk and Genrikh I. Polozov

Metabolic reprogramming of cancer by chemicals that target glutaminase isoenzymes

Volume:26
José M. Matés*, José A. Campos-Sandoval, Juan de los Santos-Jiménez, Juan A. Segura, Francisco J. Alonso and Javier Márquez

Targeting n-3 polyunsaturated fatty acids in non-alcoholic fatty liver disease

Volume:26
Rodrigo Valenzuela*, Macarena Ortiz, María Catalina Hernández-Rodas, Francisca Echeverría and Luis A. Videla

Tear Inflammatory Molecules in Contact Lens Wearers: A Literature Review

Volume:26
Alberto López-de la Rosa, María J González-García, Margarita Calonge* and Amalia Enríquez-de-Salamanca

Targeting Immune Signaling Pathways in Clonal Hematopoiesis

Volume:26
Nessar Ahmad Azrakhsh, Patrycja Mensah-glanowska, Kristoffer Sand and Astrid Olsnes Kittang*

Role of dietary gluten in development of celiac disease and type I diabetes: management beyond gluten-free diet

Volume:26
Jinli Pei, Shuangshuang Wei, Yechun Pei, Hao Wu and Dayong Wang*

Recent Advances of Chitosan and Its Derivatives in Biomedical Applications

Volume:26
Fei Ding, Jiawei Fu, Chuang Tao, Yanhua Yu, Xianran He, Yangguang Gao and Yongmin Zhang*

Microbiota, Immune System and Autism Spectrum Disorders. An Integrative Model towards Novel Treatment Options

Volume:26
Barbara Carpita, Donatella Marazziti*, Lionella Palego, Gino Giannaccini, Laura Betti and Liliana Dell'Osso

Autoimmune Hepatitis and Stellate Cells; an Insight into the Role of Autophagy

Volume:26
Shahram Golbabapour, Kamran Bagheri-Lankarani, Saeid Ghavami and Bita Geramizadeh*

Discovery and Development of Cyclin-Dependent Kinase 8 Inhibitors

Volume:26
Xiao Lv, Yongbing Tian, Shiyu Li, Kai Cheng, Xufeng Huang, Haiyan Kong, Chenzhong Liao and Zhouling Xie*

Turning fear of boron toxicity into boron-containing drug design

Volume:26
Marvin Antonio Soriano-Ursúa *, Eunice Dalet Farfán-García and Simonetta Geninatti-Crich

Obesity and body composition in man and woman: associated diseases and new role of gut microbiota

Volume:26
Ennio Avolio*, Paola Gualtieri , Lorenzo Romano, Claudio Pecorella, Simona Ferraro, Laura Di Renzo and Antonino De Lorenzo

Carnosine and diabetic nephropathy

Volume:26
Verena Peters*, Benito Yard and Claus Peter Schmitt

Obesity and cardioprotection

Volume:26
Saveria Femminò, Pasquale Pagliaro and Claudia Penna*

Nanocrystals as effective delivery systems of poorly water soluble natural molecules

Volume:26
Francesco Lai, Michele Schlich, Rosa Pireddu, Anna Maria Fadda* and Chiara Sinico

Atherosclerosis and Nanomedicine Potential: Current Advance and Future Opportunities

Volume:26
Fan Jiang, Yunqi Zhu, Changyang Gong* and Xin Wei*

Insights into the design of inhibitors of the urease enzyme – a major target for the treatment of Helicobacter pylori infections

Volume:26
Ana Thereza Fiori-Duarte, Ricardo Pereira Rodrigues, Rodrigo Rezende Kitagawa and Daniel Fábio Kawano*

LncRNAs: Potential Novel Prognostic and Diagnostic Biomarkers in Colorectal Cancer

Volume:26
Narges Dastmalchi , Reza Safaralizadeh* and Mirsaed Miri Nargesi

Quaternized Chitosan Nanoparticles in Vaccine Applications

Volume:26
Shuang Yu , Shengnan Hao, Beini Sun , Dongying Zhao , Xingye Yan and Kai Zhao*

Nanostructured calcium-based biomaterials and their application in drug delivery

Volume:26
Li-Juan Yi, Jun-Feng Li, Ming-Guo Ma* and Ying-Jie Zhu

Recent Development on Anti-Obesity Compounds and Their Mechanisms of Action: A Review

Volume:26
Yixing Qiu, Huanghe Yu , Rong Zeng, Shiyin Guo, Muhammad Daniyal, Zeyu Deng, Aibing Wang and Wei Wang*

Red and NIR Light-Responsive Polymeric Nanocarriers for On-Demand Drug Delivery

Volume:26
Xinyu He, Xianzhu Yang*, Dongdong Li and Ziyang Cao

Mitochondria Associated Membranes (MAMs): Emerging drug targets for diabetes

Volume:26
U S Swapna Sasi , G Sindhu, P Salin Raj and K G Raghu *

Diabetic Cognitive Dysfunction: From Bench to Clinic

Volume:26
Jiyin Zhou, Zuo Zhang, Hongli Zhou and Guisheng Qian*

Cardioprotective Properties Of Hdl: Structural And Functional Considerations

Volume:26
E. Pappa, M. Elisaf, C. Kostara, E. Bairaktari and V. Tsimihodimos*

Comprehensive Review On Graphene Oxide For Use In Drug Delivery System

Volume:26
Muhammad Daniyal, Bin Liu and Wei Wang*

Thioredoxin, glutathione and related molecules in tumors of the nervous system

Volume:26
Vasco Branco*, José Pimentel, Maria Alexandra Brito and Cristina Carvalho

Benzimidazole-derived compounds designed for different targets of Alzheimer’s disease

Volume:26
Hayrettin Ozan Gulcan*, Açelya Mavideniz, Mustafa Fethi Sahin and Ilkay Erdogan Orhan

Biomarkers, Biosensors and Biomedicine

Volume:26
Weslley Felix de Oliveira, Priscila Marcelino dos Santos Silva, Luana Cassandra Breitenbach Barroso Coelho and Maria Tereza dos Santos Correia*

Differential characteristics of HMGB2 versus HMGB1 and their perspectives in ovary and prostate cancer

Volume:26
María Cámara-Quílez, Aida Barreiro-Alonso, Esther Rodríguez-Bemonte, María Quindós-Varela, Esperanza Cerdán and Mónica Lamas-Maceiras*

Annexins Bend Wound Edges during Plasma Membrane Repair

Volume:26
Adam Cohen Simonsen*, Theresa Louise Boye and Jesper Nylandsted*

Therapeutic applications of Peptides against Zika Virus: A Review

Volume:26
Preeti Karwal, Ishwar Dutt Vats, Niharika Sinha, Anchal Singhal, Teena Sehgal and Pratibha Kumari*

Reversine: A Synthetic Purine with a Dual Activity as a Cell Dedifferentiating Agent and a Selective Anticancer Drug

Volume:26
Marco Piccoli, Andrea Ghiroldi, Michelle M. Monasky, Federica Cirillo, Giuseppe Ciconte, Carlo Pappone and Luigi Anastasia*

Vanadium and Oxidative Stress Markers – In Vivo Model: a review

Volume:26
Agnieszka Ścibior* and Joanna Kurus

Lanthanum, Gallium and Their Impact on Oxidative Stress

Volume:26
Lozan Todorov*, Irena Kostova and Maria Traykova

Glycan Carriers As Glycotools For Medicinal Chemistry Applications

Volume:26
Mattia Vacchini, Rana Edwards, Roberto Guizzardi, Alessandro Palmioli, Carlotta Ciaramelli, Alice Paiotta, Cristina Airoldi, Barbara La Ferla and Laura Cipolla*

Recent progresses in Organic-Inorganic Nano technological platforms for cancer therapeutics

Volume:26
Sanjay Kumar, Anchal Singhal, Uma Narang, Sweta Mishra and Pratibha Kumari*

Targeting tumour metastasis: the emerging role of nanotechnology

Volume:26
Sarah Visentin, Mirela Sedić, Sandra Kraljević Pavelić and Krešimir Pavelić*

Cardiovascular effects of flavonoids

Volume:26
Manuel Sanchez, Miguel Romero, Manuel Gómez-Guzman, Juan Tamargo, Francisco Pérez-Vizcaino and Juan Duarte*

Hybrid imidazole-pyridine derivatives: an approach to novel anticancer DNA intercalators

Volume:26
Claudiu N. Lungu*, Bogdan Ionel Bratanovici , Grigore Maria Mirabela , Vasilichia Antoci and Ionel I. Mangalagiu*

Selective MMP-13 inhibitors: promising agents for the therapy of Osteoarthritis

Volume:26
Yichao Wan*, Wei Li, Zhipeng Liao, Mi Yan, Xuwang Chen* and Zilong Tang

Nitric Oxide in Life and Death of Neutrophils

Volume:26
Svetlana I. Galkina , Ekaterina A. Golenkina , Galina M. Viryasova , Yulia M. Romanova and Galina F. Sud’ina *

Unlocking the potential of HK2 in cancer metabolism and therapeutics

Volume:26
Sara N. Garcia , Rita C. Guedes and M. Matilde Marques*

Structure and function of L,D- and D,D-transpeptidase family enzymes from Mycobacterium tuberculosis

Volume:26
Gideon F. Tolufashe, Victor T. Sabe, Colins U. Ibeji, Thandokuhle Ntombela, Thavendran Govender, Glenn E. M. Maguire, Hendrik G. Kruger, Gyanu Lamichhane and Bahareh Honarparvar*

Discovery of Dengue Virus Inhibitors

Volume:26
Adib Afandi Abdullah, Yean Kee Lee, Sek Peng Chin, See Khai Lim, Vannajan Lee, Rozana Othman, Shatrah Othman, Noorsaadah Abdul Rahman, Rohana Yusof and Choon Han Heh*

Tansition Metal-Based Prodrugs for Anticancer Drug Delivery

Volume:26
Ana Maria Faísca Phillips* and Armando J. L. Pombeiro

Oxazole-based compounds as anticancer agents

Volume:26
Maria A. Chiacchio*, Giuseppe Lanza, Ugo Chiacchio, Salvatore V. Giofrè, Roberto Romeo, Daniela Iannazzo and Laura Legnani

Structural Basis for Inhibition of Enoyl-[Acyl Carrier Protein] Reductase (InhA) from Mycobacterium tuberculosis

Volume:26
Maurício Boff de Ávila, Gabriela Bitencourt-Ferreira and Walter Azevedo*

Recent advances in multi-target anti-Alzheimer disease compounds (2013 up to present)

Volume:26
Ning Wang, Panpan Qiu, Wei Cui, Bin Zhang, Xiaojun Yan and Shan He*

Novel Vaccine Candidates against Tuberculosis

Volume:26
Zhihao Li, Changping Zheng, Marco Terreni, Lisa Tanzi, Matthieu Sollogoub and Yongmin Zhang*

Carbon nano-onions: a valuable class of carbon nanomaterials in biomedicine

Volume:26
Silvia Giordani*, Adalberto Camisasca and Viviana Maffeis

Advances in carbon based nanomaterials for bio-medical applications

Volume:26
Tejendra Kumar Gupta, Pattabhi Ramaiah Budarapu*, Sivakumar Reddy Chappidi, Sudhir YB Sastry, Marco Paggi and Stephane PA Bordas

The Structural Details of Aspirin Molecules and Crystals.

Volume:25
Ana Maria Toader, Snezana D. Zaric, Christina M. Zalaru and Marilena Ferbinteanu*

Development of topical nanocarriers for skin cancer treatment using Quality by Design approach

Volume:25
Erzsebet Csanyi*, Mónika Bakonyi, Anita Kovács, Mária Budai-Szűcs, Ildikó Csóka and Szilvia Berkó

Tuberculosis – present medication and therapeutic prospects

Volume:25
Anna Jeliñsk, Marianna Zając, Adrianna Dadej, Szymon Tomczak, Małgorzata Geszke-Moritz and Izabela Muszalska*

Use of hemoglobin for delivering exogenous carbon monoxide in medicinal applications

Volume:25
Kazuaki Taguchi*, Toru Maruyama and Masaki Otagiri *

Anthocyanins As Modulators of Cell Redox-Dependent Pathways in Non-Communicable Diseases

Volume:25
Antonio Speciale, Antonella Saija, Romina Bashllari, Maria Sofia Molonia, Claudia Muscara, Cristina Occhiuto, Francesco Cimino* and Mariateresa Cristani

Pharmaceutical Mixtures: Still A Concern For Human And Environmental Health

Volume:25
Georgeta M. Simu, Jeanne Atchana , Codruta M. Soica, Dorina E. Coricovac, Sebastian C. Simu and Cristina A. Dehelean*

How Often are Orphan Drugs Orphaned by the Thermochemical Community?

Volume:25
Kathleen F. Edwards and Joel F. Liebman*

Aim for the readers! Bromodomains as new targets against Chagas’ disease

Volume:25
Victoria Lucia Alonso, Luis Emilio Tavernelli, Alejandro Pezza, Pamela Cribb, Carla Ritagliati and Esteban Carlos Serra*

Natural compounds therapeutic features in brain disorders by experimental, bioinformatics and cheminformatics methods

Volume:25
Speranta Avram, Alin Puia, Ana Maria Udrea, Dan Mihailescu, Maria Mernea*, Anca Dinischiotu, Florin Oancea and Johan Stiens

Current Development of Metal Complexes with Diamine Ligands as Potential Anticancer Agents

Volume:25
Sonja T Misirlic-Dencic*, Jelena Poljarevic, Andjelka M Isakovic, Tibor Sabo, Ivanka Markovic and Vladimir Trajkovic

Linseed essential oil – Source of Lipids as Active Ingredients for Pharmaceuticals and Nutraceuticals

Volume:25
Joana Campos , Patricia Severino, Classius Ferreira, A Zielinska, Antonello Santini, Selma Souto and Eliana B. Souto*

Novel Chemotherapeutic Agents - The Contribution of Scorpionates

Volume:25
Marta Amaral Andrade and Luísa M.D.R.S. Martins*