Current Medicinal Chemistry

This journal supports open access

Editor-in-Chief:

Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

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Meet Our Editorial Board Member free to download

Volume:26   Issue: 36
Pp: 6515-6516
Doris Mangiaracina Benbrook
DOI: 10.2174/092986732636191202125321



Chagas Disease Treatment: From New Therapeutic Targets to Drug Discovery and Repositioning free to download

Volume:26   Issue: 36
Pp: 6517-6518
Mariana R. Miranda and Melisa M. Sayé
DOI: 10.2174/092986732636191202125919



Dynamics of T Cells Repertoire During Trypanosoma cruzi Infection and its Post-Treatment Modulation

Volume:26   Issue: 36
Pp: 6519-6543
Adriana Egui, Paola Lasso, Elena Pérez-Antón, M. Carmen Thomas and Manuel Carlos López*
DOI: 10.2174/0929867325666181101111819



Aim for the Readers! Bromodomains As New Targets Against Chagas’ Disease

Volume:26   Issue: 36
Pp: 6544-6563
Victoria Lucia Alonso, Luis Emilio Tavernelli, Alejandro Pezza, Pamela Cribb, Carla Ritagliati and Esteban Serra*
DOI: 10.2174/0929867325666181031132007



NADPH Producing Enzymes as Promising Drug Targets for Chagas Disease

Volume:26   Issue: 36
Pp: 6564-6571
Artur T. Cordeiro*
DOI: 10.2174/0929867325666181009152844



Signal Transduction Pathways as Therapeutic Target for Chagas Disease

Volume:26   Issue: 36
Pp: 6572-6589
Alejandra Cecilia Schoijet, Tamara Sternlieb and Guillermo Daniel Alonso*
DOI: 10.2174/0929867326666190620093029



Repositioning of HIV Aspartyl Peptidase Inhibitors for Combating the Neglected Human Pathogen Trypanosoma cruzi

Volume:26   Issue: 36
Pp: 6590-6613
Leandro S. Sangenito*, Rubem F.S. Menna-Barreto, Cláudia M. d'Avila-Levy, Marta H. Branquinha* and André L.S. Santos*
DOI: 10.2174/0929867326666190610152934



The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies

Volume:26   Issue: 36
Pp: 6614-6635
Alan Talevi, Carolina Carrillo and Marcelo Comini*
DOI: 10.2174/0929867325666180926151059



Amino Acid and Polyamine Membrane Transporters in Trypanosoma cruzi: Biological Function and Evaluation as Drug Targets

Volume:26   Issue: 36
Pp: 6636-6651
Melisa Sayé, Chantal Reigada, Lucrecia Gauna, Edward A. Valera-Vera, Claudio A. Pereira* and Mariana R. Miranda
DOI: 10.2174/0929867326666190620094710



Drug Target Selection for Trypanosoma cruzi Metabolism by Metabolic Control Analysis and Kinetic Modeling

Volume:26   Issue: 36
Pp: 6652-6671
Emma Saavedra*, Zabdi González-Chávez, Rafael Moreno-Sánchez and Paul A.M. Michels*
DOI: 10.2174/0929867325666180917104242



Target-based Screening of the Chagas Box: Setting Up Enzymatic Assays to Discover Specific Inhibitors Across Bioactive Compounds

Volume:26   Issue: 36
Pp: 6672-6686
Emir Salas-Sarduy, Gabriela T. Niemirowicz, Juan José Cazzulo and Vanina E. Alvarez*
DOI: 10.2174/0929867326666190705160637