ISSN (Print): 1566-5240
ISSN (Online): 1875-5666
Volume 20, 10 Issues, 2020
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ISSN (Print): 1566-5240
ISSN (Online): 1875-5666
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Editor(s): Alessandra Pagliarani, Fabiana Trombetti and Vittoria Ventrella
eISBN: 978-1-60805-265-3, 2012
Organotins are widespread contaminants especially of water environments. Their chemically versatile structure makes organotin compounds able to bind to a variety of biomolecules thus widely affecting biological functions. Trisubstituted molecules, namely tributyltin (TBT) and triphenyltin (TPhT), have been widely employed in antifouling paints and are also exploited as plastic stabilizers that unfortunately cause harmful biological effects. Persistent bioaccumulation has resulted in organotins becoming a significant environmental threat. Chapter by chapter, the biological and biochemical effects of organotins are unravelled in this e-book by a careful analysis of the most recent findings with special focus on contaminant action mechanisms at cellular and molecular level. The e-book provides an intriguing insight into the molecular mechanisms involved in organotin toxicology thus serving as a useful reference to biochemists, biologists, ecotoxicologists and life science students.
Author(s): Olivier Renaudet and Nicolas Spinelli
eISBN: 978-1-60805-277-6, 2011
The interactions between carbohydrates and proteins have been extensively explored in a wide range of physiological and pathological processes over several decades. The recent emergence of glycomics has strengthened this interest and notably contributed to spectacular progress in understanding how carbohydrates mediate and regulate complex biological events. Synthesis and Biological Applications of Glycoconjugates gives a summary of contemporary findings in glycoconjugate research. Readers will be updated on major achievements in chemical methods and biological applications employed in modern glycomics. The Ebook should be of interest to a broad community of students and professional researchers in both academia and industry.
Editor(s): John A. Dangerfield
Co-Editor(s): Christoph Metzner
eISBN: 978-1-60805-123-6, 2010
This Ebook aims to review basic understandings and give current opinions about several important aspects of glycosylphosphatidylinositol-anchored (GPI) protein biology from leading experts in this exciting and emerging field. The scope ranges from micro-domain localization and signaling to proteomics aspects, biophysical behavior through trans-cellular mobility to chemical synthesis of GPI mimics and finally modification of multi-scaled membrane surfaces and potential medical and biotech uses. The applied slant makes it very useful to the current state of knowledge. It is hoped that it will prove to be of considerable interest to students and researchers in this field.
Editor(s): Maricela Rodriguez-Cruz
Co-Editor(s): Mardia López-Alarcón
eISBN: 978-1-60805-177-9, 2011
This E-book covers the main aspects about the benefits of omega-3 long chain polyunsaturated fatty acids (LC-PUFAs) to human health. The knowledge of physiological effects of LC-PUFAs at different levels is constantly expanding. Topics covered over 10 chapters thoroughly detail the role of omega-3 LCPUFAs in nutrition (gene regulation) and disease (clinical applications); information about food sources and recent intake recommendations is also explained. This book also discusses current data concerning the role of LC-PUFAs during pregnancy and lactation, in cognitive function, immune response, allergy, asthma, cardiovascular diseases, depression, obesity, and insulin resistance. The book should be useful for advanced graduate students, public health officials as well as researchers working with LC-PUFAs.
Editor(s): Vaclav Vetvicka
Co-Editor(s): Miroslav Novak
eISBN: 978-1-60805-210-3, 2011
ISBN: 978-1-60805-706-1 ISSN: 2211-0526 (Print)
β-Glucan is generally considered to be a very safe immunomodulator. It is a well-known biological response modifier (BRM) that has been used as an adjuvant therapy for cancer since 1980, mostly in Japan. β-Glucan enhances the innate host defense against certain bacteria, yeast, and viral pathogens. I addition, glucans are also considered to be important in prophylaxis against irradiation. Various types of glucans are now routinely added both to human and animal food. At least 26 clinical trials are currently under way in several countries. The authors of this ebook have selected and brought together information on both theoretical and practical aspects of β-glucan use. The book is suitable for readers seeking timely and precise information on β-glucan history and various biological effects including possible use in the treatment of various diseases, without having any preliminary knowledge of natural immunomodulators. The book should not only provide an inspiration for carbohydrate and clinical chemists for further investigations in biomedicine, but it also presents a number of practical applicable results in immunology
Author(s): Y. Robert Li
eISBN: 978-1-60805-322-3, 2012
Free radicals and related reactive species, including reactive oxygen and nitrogen species (ROS/RNS) play a critical role in the pathophysiological processes of various human diseases, including cardiovascular diseases, diabetes and metabolic syndrome, neurological disorders, and cancer among many others. This peer-reviewed E-book covers both the fundamental principles and the recent advances in free radical biomedicine along with in-depth discussions of the clinical correlations. It also provides a thorough coverage of the commonly used methods in free radical and antioxidant research with detailed schematic illustrations as well as succinct descriptions of the procedures. This volume should also be a valuable source of information for readers who wish to gain a sound understanding of the research methodologies in this rapidly evolving field.
Editor(s): Joe Tiralongo and Ivan Martinez-Duncker
eISBN: 978-1-60805-386-5, 2013
This eBook presents a summary of central aspects of sialobiology (i.e., the study of sialic acid and its relevance to biology). The importance of substitution by the sugar sialic acid and the role played by sialylated structures (eg. glycoproteins, glycolipids, glycoconjugates) in immune recognition, neural cell growth, embryogenesis and disease development including microbial pathogenesis and cancer progression, has become well-established.
Since 1995, the field of sialobiology has expanded greatly as many of the key enzymes involved in sialic acid biosynthesis, as well as the vast majority of sialic acid binding lectins involved in immune recognition, have only been cloned, characterised and structural eluciated after the publication of earlier works on the subject. This e-book also covers these recent developments. Chapters in this e-book have been contributed by eminent sialobiologists. Therefore, a book of this nature is timely and will prove to be a definitive volume with a high impact in this field for glycobiologists and cell biologists.
Author(s): Maddaly Ravi
eISBN: 978-1-60805-944-7, 2014
ISBN: 9778-1-60805-945-4 ISSN: 2352-8745 (Print)
Today’s academic environment presents assessment challenges defined by an increased volume of available information coupled with increased competition among students and time constraints. Multiple choice questions (MCQs) provide examiners with an opportunity to assess academic performance on the basis of instant recollection of correct answers in a minimal amount of time.
MCQs Series for Life Sciences Volume 1 is a collection of MCQs on advanced topics and offers the following benefits for readers:
Includes over 2600 relevant MCQs
Covers five advanced subjects including biochemistry, cell biology, developmental biology, genetics & molecular biology and immunology.
Simplified language and presentation of concepts
Answers to each question are provided
This MCQs eBook series in life sciences is, therefore, a handy reference for graduate and postgraduate students undertaking examinations or entrance tests as well as teachers or examiners involved in setting and controlling assessments in specific subjects in life sciences.
eISBN: 978-1-68108-639-2, 2018
ISBN: 978-1-68108-640-8 ISSN: 2468-2365 (Print) ISSN: 2352-8745 (Online)
Today's academic environment presents assessment challenges defined by an increased volume of available information coupled with increased competition among students and time constraints. Multiple choice questions (MCQs) provide examiners with an opportunity to assess academic performance on the basis of instant recollection of correct answers in a minimal amount of time.
MCQs Series for Life Sciences Volume 2 is a collection of MCQs on advanced topics and offers the following benefits for readers:
o Includes over 950 relevant MCQs
o Covers two major topics: cell culture and microbiology.
o Simplified language and presentation of concepts
o Answers to each question are provided
This MCQ book series in life sciences is a handy reference for graduate and postgraduate students undertaking examinations or entrance tests as well as teachers or examiners involved in setting and controlling assessments in specific subjects in life sciences.
Author(s): A.K.M. Shamsuddin and Guang-Yu Yang
eISBN: 978-1-68108-007-9, 2015
Inositol and its phosphates are ubiquitous across most life forms, wherein they play important roles in cellular integrity and functions such as signal transduction, DNA damage repair ion transport and mRNA transport. This reference details the biochemistry and industrial applications of inositol and its phosphate derivatives. Topics covered in this book include the use of inositol and its hexaphosphate (IP6) for numerous health benefits – as antioxidants, as an anti-cancer drug, for the management of atherosclerosis, diabetes, osteoporosis, Alzheimer’s disease, sickle cell anemia, and even in fighting tooth decay. Readers will also learn about Industrial applications of Inositol including preservation of food and wine, nanotechnology, lithium ion battery, fuel cell technology etc.
Inositol & its Phosphates: Basic Science to Practical Applications is a valuable reference for any researcher or aspiring biomedical professional seeking to know more about this fascinating metabolite.
Editor(s): Jacky J. Cosson
eISBN: 978-1-68108-128-1, 2015
Experimental research using spermatozoa, a highly specialized cell with organelles involved in gene transfer, energy supply and cellular motility, has always occupied the forefront of studies in cell and reproductive biology. Several spermatological experiments have focused on the attraction of a spermatozoon toward the egg – sperm chemotaxis or sperm guidance. This process ubiquitously occurs in the reproductive system of many organisms. After its discovery in the late 19th century in plants, sperm chemotaxis is known to play a crucial role in fertilization success in both plants and animals. Spermatology has expanded in focus in recent years, as the structure of molecules relevant to sperm chemotaxis has been recently determined in several species of invertebrates and vertebrates, which promises remarkable progress for understanding events relevant to sexual reproduction. Reflecting upon these trends in the long history of sperm chemotaxis, Flagellar Mechanics and Sperm Guidance gathers leaders in the field of spermatology, who have presented their experimental research on the chemical cues behind flagellate behavior in a variety of organisms including bikonts and spermatozoa of marine invertebrates and vertebrates (fish, amphibians and mammals). Reviews presented in this monograph provide both basic and detailed information on the initiation and activation of sperm motility at spawning, sperm thermotaxis, and other mechanics such as mathematical models of a spermatozoon swimming. A comparison between features of sperm chemotaxis among different organisms is also given.
Flagellar Mechanics and Sperm Guidance will stir interest in spermatology research among a broad variety of readers including researchers, Ph.D. students studying reproductive biology and teachers involved in advanced biology courses.
Editor(s): Luis Rodrigues da Silva and Branca Silva
eISBN: 978-1-68108-239-4, 2016
Plants have been widely used to treat diseases, owing to the presence of bioactive compounds (phytochemicals) which play important roles in health promotion and disease prevention. In recent years, advances in chemical extraction techniques, lifestyle and dietary choices for human health have increased the interest in the consumption and study of fruits, vegetables, and foods enriched with bioactive compounds and nutraceuticals. Thousands of dietary phytochemicals, such as flavonoids, phenolic acids, glucosinolates, terpenes and alkaloids, have been identified and categorized further according to a diverse array of biochemical properties. Many of these phytochemicals have been hypothesized to reduce the risk of several pathological conditions which include life threatening diseases such as heart disease and cancer, to name a few.
Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters is a 2 book set which presents a summary of different classes of phytochemicals commonly found in common edible food sources. Each chapter details the general chemical structures of compounds, naturally present in specific fruits, vegetables and grains, their biological importance and mechanisms of action.
The book set is an essential handbook for anyone interested in the natural product chemistry of these common crops.
Part 1 of this set covers details about different fruits (banana, citrus fruits, pears, etc.). Part 2 covers legumes, nuts, seeds and cereals.