Current Molecular Medicine

Editors-in-Chief:

David W. Li (China)
Andras Guttman (Hungary)

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Editorial: [Exciting Discoveries About New p53 Target Genes, Cancer Drugs and Diagnostic Tools, and Mechanisms of Various Human Diseases] free to download

Volume:12   Issue: 8
Pp: 899-900
David Wan-Cheng
DOI: 10.2174/156652412802480934

The p53-Bak Apoptotic Signaling Axis Plays an Essential Role in Regulating Differentiation of the Ocular Lens

Volume:12   Issue: 8
Pp: 901-916
M. Deng, P. Chen, F. Liu, S. Fu, H. Tang, Y. Fu, Z. Xiong, S. Hui, W. Ji, X. Zhang, L. Zhang, L. Gong, X. Hu, W. Hu, S. Sun, J. Liu, L. Xiao, W. -B. Liu, Y. -M. Xiao, S. -J. Liu, Y. Liu and D. W.-C. Li
DOI: 10.2174/156652412802480899

The Tumor Suppressor p53 Regulates c-Maf and Prox-1 to Control Lens Differentiation

Volume:12   Issue: 8
Pp: 917-928
F. -Y. Liu, X. -C. Tang, M. Deng, P. Chen, W. Ji, X. Zhang, L. Gong, Z. Woodward, J. Liu, L. Zhang, S. Sun, J. -P. Liu, K. Wu, M. -X. Wu, X. -L. Liu, M. -B. Yu, Y. Liu and D. W.-C. Li
DOI: 10.2174/156652412802480835

p53 is an Important Regulator of CCL2 Gene Expression

Volume:12   Issue: 8
Pp: 929-943
X. Tang, M. Asano, A. O’Reilly, A. Farquhar, Y. Yang and S. Amar
DOI: 10.2174/156652412802480844

Multiple Target-Specific Molecular Imaging Agents Detect Liver Cancer in a Preclinical Model open access plus

Volume:12   Issue: 8
Pp: 944-951
S. Ke, F. Zhang, W. Wang, X. Qiu, J. Lin, A. G. Cameron, C. Zou, X. Gao, C. Zou, V. F. Zhu and M. Li
DOI: 10.2174/156652412802480952

Andrographolide Inhibits Osteopontin Expression and Breast Tumor Growth Through Down Regulation of PI3 Kinase/Akt Signaling Pathway

Volume:12   Issue: 8
Pp: 952-966
S. Kumar, H. S. Patil, P. Sharma, D. Kumar, S. Dasari, V. G. Puranik, H. V. Thulasiram and G. C. Kundu
DOI: 10.2174/156652412802480826

Plumbagin Inhibits Breast Tumor Bone Metastasis and Osteolysis by Modulating the Tumor-Bone Microenvironment

Volume:12   Issue: 8
Pp: 967-981
Z. Li, J. Xiao, X. Wu, W. Li, Z. Yang, J. Xie, L. Xu, X. Cai, Z. Lin, W. Guo, J. Luo and M. Liu
DOI: 10.2174/156652412802480871

The PP2A-Aβ Gene is Regulated by Multiple Transcriptional Factors Including Ets-1, SP1/SP3, and RXRα /β

Volume:12   Issue: 8
Pp: 982-994
J. Liu, W. Ji, S. Sun, L. Zhang, H. -G. Chen, Y. Mao, L. Liu, X. Zhang, L. Gong, M. Deng, L. Chen, W. -J. Han, P. -C. Chen, W. -F. Hu, X. Hu, J. Liu, Z. Woodward, W. -B. Liu, Y. -M. Xiao, S. -P. Liang, Y. Liu, S. -J. Liu and D. W.-C. Li
DOI: 10.2174/156652412802480916

Selenite Benefits Embryonic Stem Cells Therapy in Parkinson’s Disease

Volume:12   Issue: 8
Pp: 1005-1014
L. -P. Tian, S. Zhang, L. Xu, W. Li, Y. Wang, S. -D. Chen and J. -Q. Ding
DOI: 10.2174/156652412802480880

siRNA Silencing of Gene Expression in Trabecular Meshwork: RhoA siRNA Reduces IOP in Mice

Volume:12   Issue: 8
Pp: 1015-1027
Q. Liu, K. Wu, X. Qiu, Y. Yang, X. Lin and M. Yu
DOI: 10.2174/156652412802480907

Medaka piwi is Essential for Primordial Germ Cell Migration

Volume:12   Issue: 8
Pp: 1040-1049
M. Li, N. Hong, J. Gui and Y. Hong
DOI: 10.2174/156652412802480853

In Vitro Regulatory Effect of Epididymal Serpin CRES on Protease Activity of Proprotein Convertase PC4/PCSK4

Volume:12   Issue: 8
Pp: 1050-1067
P. Mishra, Q. Qiu, A. Gruslin, Y. Hidaka, M. Mbikay and A. Basak
DOI: 10.2174/156652412802480961

Targeting the Tumor Proteasome as a Mechanism to Control the Synthesis and Bioactivity of Matrix Macromolecules

Volume:12   Issue: 8
Pp: 1068-1082
S. S. Skandalis, A. J. Aletras, C. Gialeli, A. D. Theocharis, N. Afratis, G. N. Tzanakakis and N. K. Karamanos
DOI: 10.2174/156652412802480943

Structure, Function and Control of Complement C5 and its Proteolytic Fragments

Volume:12   Issue: 8
Pp: 1083-1097
N. S. Laursen, F. Magnani, R. H. Gottfredsen, S. V. Petersen and G. R. Andersen
DOI: 10.2174/156652412802480925