Current Molecular Medicine

Editors-in-Chief:

David W. Li (China)
Andras Guttman (Hungary)

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Open Access Articles

Expression Suppression and Activity Inhibition of TRPM7 Regulate Cytokine Production and Multiple Organ Dysfunction Syndrome During Endotoxemia: a New Target for Sepsis open Access plus

Volume: 19   Issue: 8
Pp: 547-559
Sebastian Gatica, Felipe Eltit, Juan F. Santibanez, Diego Varela, Claudio Cabello-Verrugio and Felipe Simon*
DOI:10.2174/1566524019666190709181726

Stem Cells as a Resource for Treatment of Infertility-related Diseases open Access plus

Volume: 19   Issue: 8
Pp: 539-546
Jing Wang, Chi Liu, Masayuki Fujino, Guoqing Tong, Qinxiu Zhang, Xiao-Kang Li* and Hua Yan*
DOI:10.2174/1566524019666190709172636

Risk Factor for Residue After Uterine Artery Chemotherapy and Embolization in Combination with Dilatation and Curettage for Treating Caesarean Scar Pregnancy open Access plus

Volume: 19   Issue: 7
Pp: 525-531
Feng Cheng, Dan Shan, Sijia Guo, Shuang Cheng, Hongwei Yang, Jialin Han and Tongxiu Hu*
DOI:10.2174/1566524019666190612135728

Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water open Access plus

Volume: 19   Issue: 4
Pp: 294-302
Xiangzi Li, Liangtong Li, Xuanchen Liu, Jiawen Wu, Xiaoyu Sun, Zhilin Li, Yong-Jian Geng, Fulin Liu* and Yujuan Zhou*
DOI:10.2174/1566524019666190321113544

Naoxintong Retards Atherosclerosis by Inhibiting Foam Cell Formation Through Activating Pparα Pathway open Access plus

Volume: 18   Issue: 10
Pp: 698-710
Zeng Wang, Huairui Shi, Huan Zhao, Zhen Dong, Buchang Zhao, Xinyu Weng, Rongle Liu, Xiao Li, Kai Hu, Yunzeng Zou, Aijun Sun* and Junbo Ge *
DOI:10.2174/1566524019666190207143207

Potential Mutations in Chinese Pathologic Myopic Patients and Contributions to Phenotype open Access plus

Volume: 18   Issue: 10
Pp: 689-697
L. Chen, Y. Wei, W. Chi, D. Fang, X. Jiang and S. Zhang*
DOI:10.2174/1566524019666190211120016

Small Incision Femtosecond Laser-assisted X-ray-irradiated Corneal Intrastromal Xenotransplantation in Rhesus Monkeys: A Preliminary Study open Access plus

Volume: 18   Issue: 9
Pp: 612-621
He Jin, Liangping Liu, Hui Ding, Miao He, Chi Zhang and Xingwu Zhong*
DOI:10.2174/1566524019666190129123935

Comparison of Small-incision Femtosecond Laser-assisted Intrastromal Keratoplasty and Lamellar Keratoplasty in Rhesus Monkeys Using Xenogenic Corneal Lamellae open Access plus

Volume: 18   Issue: 6
Pp: 365-375
He Jin, Miao He, Wei Wang, Hongshan Liu, Xiaoying Zhong, Liangping Liu, Hui Ding and Xingwu Zhong*
DOI:10.2174/1566524018666181109120023

Oxidative Stress in Cerebral Small Vessel Disease Dizziness Patients, Basally and After Polyphenol Compound Supplementation open Access plus

Volume: 18   Issue: 3
Pp: 160-165
L. Ulivi, M. Maccarrone, N. Giannini, E. Ferrari, M.C. Caselli, V. Montano, L. Chico, A. Casani, E. Navari, N. Cerchiai, G. Siciliano, U. Bonuccelli and M. Mancuso*
DOI:10.2174/1566524018666180720165055

Decreased Expression of TIM-3 on Th17 Cells Associated with Ophthalmopathy in Patients with Graves’ Disease open Access plus

Volume: 18   Issue: 2
Pp: 83-90
J. Zhao, B. Lin, H. Deng, X. Zhi, Y. Li, Y. Liu, P.W. Bible, Q. Li, B. Xu, L. Wei, H. Yang* and D. Huang*
DOI:10.2174/1566524018666180705105753

ZNF424 Induces Apoptosis and Inhibits Proliferation in Lung Carcinoma Cells open Access plus

Volume: 18   Issue: 2
Pp: 109-115
W. Liu, W. Yuan, X. Li, J. Zhuang, X. Mo, G. Dai, Y. Wang, J. Chen, Y. Wan, Y. Li, X. Zhu, Y. Chen, S. Luo, Z. Jiang, Y. Shi, F. Chen, L. Cao, X. Ye, X. Fan*, P. Zhu*, K. Zhang* and X. Wu*
DOI:10.2174/1566524018666180705113642

Decreased Expression of MYPT1 Contributes to Tumor Angiogenesis and Poor Patient Prognosis in Human Prostate Cancer open Access plus

Volume: 18   Issue: 2
Pp: 100-108
Y. Liang, Y. Zhuo, Z. Lin, F. Jiang, Q. Dai, J. Lu, W. Dong, X. Zhu, Z. Han* and W. Zhong*
DOI:10.2174/1566524018666180705111342

Intraepithelial Attack Rather than Intratumorally Infiltration of CD8+T Lymphocytes is a Favorable Prognostic Indicator in Pancreatic Ductal Adenocarcinoma open Access plus

Volume: 17   Issue: 10
Pp: 689-698
J. Zhang, Y.F. Wang, B. Wu, Z.X. Zhong, K.X. Wang, L.Q. Yang, Y.Q. Wang, Y.Q. Li, J. Gao* and Z.S. Li*
DOI:10.2174/1566524018666180308115705

ROCK Inhibitor Y-27632 Promotes Human Retinal Pigment Epithelium Survival by Altering Cellular Biomechanical Properties open Access plus

Volume: 17   Issue: 9
Pp: 637-646
Y. Ni, Y. Qin, Z. Fang and Z. Zhang*
DOI:10.2174/1566524018666180316150936

Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development open Access plus

Volume: 17   Issue: 9
Pp: 627-636
F. Chen, W. Yuan, X. Mo, J. Zhuang, Y. Wang, J. Chen, Z. Jiang, X. Zhu, Q. Zeng, Y. Wan, F. Li, Y. Shi, L. Cao, X. Fan, S. Luo, X. Ye, Y. Chen, G. Dai, J. Gao, X. Wang, H. Xie*, P. Zhu*, Y. Li* and X. Wu*
DOI:10.2174/1566524018666180308113909

The bHLH Protein Nulp1 is Essential for Femur Development Via Acting as a Cofactor in Wnt Signaling in Drosophila open Access plus

Volume: 17   Issue: 7
Pp: 509-517
Q. Zeng, Y. Wan, P. Zhu, M. Zhao, F. Jiang, J. Chen, M. Tang, X. Zhu, Y. Li, H. Zha, Y. Wang, M. Hu, X. Mo, Y. Zhang, Y. Chen, Y. Chen, X. Ye, R. Bodmer, K. Ocorr, Z. Jiang*, J. Zhuang*, W. Yuan* and X. Wu*
DOI:10.2174/1566524018666180212145714

A Low Concentration of Tacrolimus/Semifluorinated Alkane (SFA) Eyedrop Suppresses Intraocular Inflammation in Experimental Models of Uveitis open Access plus

Volume: 17   Issue: 3
Pp: 211-220
S. De Majumdar, M. Subinya, J. Korward, A. Pettigrew, D. Scherer and H. Xu*
DOI:10.2174/1566524017666170807144009

Gene Expression Meta-Analysis of Potential Metastatic Breast Cancer Markers open Access plus

Volume: 17   Issue: 3
Pp: 200-210
R. Bell, R. Barraclough and O. Vasieva*
DOI:10.2174/1566524017666170807144946

Proteotoxic Stress Desensitizes TGF-beta Signaling Through Receptor Downregulation in Retinal Pigment Epithelial Cells open Access plus

Volume: 17   Issue: 3
Pp: 189-199
X. Tan, C. Chen, Y. Zhu, J. Deng, X. Qiu, S. Huang, F. Shang, B. Cheng* and Y. Liu*
DOI:10.2174/1566524017666170619113435

CXCR7 Participates in CXCL12-mediated Cell Cycle and Proliferation Regulation in Mouse Neural Progenitor Cells open Access plus

Volume: 16   Issue: 8
Pp: 738-746
Y. Wang, P. Xu, L. Qiu, M. Zhang, Y. Huang and J.C. Zheng
DOI:10.2174/1566524016666160829153453

Serum miRNAs Signature Plays an Important Role in Keloid Disease open Access plus

Volume: 16   Issue: 5
Pp: 504-514
Y. Luan, Y. Liu, C. Liu, Q. Lin, F. He, X. Dong and Z. Xiao
DOI:10.2174/1566524016666160429121345

STAT3 Activation in Circulating Monocytes Contributes to Neovascular Age-Related Macular Degeneration open Access plus

Volume: 16   Issue: 4
Pp: 412-423
M. Chen, J. Lechner, J. Zhao, L. Toth, R. Hogg, G. Silvestri, A. Kissenpfennig, U. Chakravarthy and H. Xu
DOI:10.2174/1566524016666160324130031

DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction open Access plus

Volume: 16   Issue: 1
Pp: 91-102
D. Zou, L. Chen, D. Deng, D. Jiang, F. Dong, C. McSweeney, Y. Zhou, L. Liu, G. Chen, Y. Wu and Y. Mao
DOI:10.2174/1566524016666151222150024

Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-infected Patients Treated with Highly Active Antiretroviral Therapy (HAART). open Access plus

Volume: 15   Issue: 10
Pp: 975-979
Z. Dai, W. Cai, F. Hu, Y. Lan, L. Li, C. Chung, B. Caughey, K. Zhang and X. Tang
DOI:10.2174/1566524016666151123114401

Thymic Nurse Cells Participate in Heterotypic Internalization and Repertoire Selection of Immature Thymocytes; Their Removal from the Thymus of Autoimmune Animals May be Important to Disease Etiology open Access plus

Volume: 15   Issue: 9
Pp: 828-835
J. C. Guyden, M. Martinez, R. V.E. Chilukuri, V. Reid, F. Kelly and M. -O.D. Samms
DOI:10.2174/1566524015666151026102328

Cell-in-cell phenomenon: A New Paradigm in Life Sciences. open Access plus

Volume: 15   Issue: 9
Pp: 810-818
X. Wang
DOI:10.2174/1566524015666151026095730

Integrins as Therapeutic Targets for Respiratory Diseases open Access plus

Volume: 15   Issue: 8
Pp: 714-734
C. M. Teoh, S. S.L. Tan and T. Tran
DOI:10.2174/1566524015666150921105339

Role of microRNAs in Vascular Remodeling open Access plus

Volume: 15   Issue: 8
Pp: 684-696
Y. -C. Fang and C. -H. Yeh
DOI:10.2174/1566524015666150921105031

Salivary Gland Dysplasia in Fgf10 Heterozygous Mice: A New Mouse Model of Xerostomia open Access plus

Volume: 15   Issue: 7
Pp: 674-682
A.J. May, L. Chatzeli, G.B. Proctor and A.S. Tucker
DOI:10.2174/1566524015666150831141307

Selective Inhibition of SIRT2 Improves Outcomes in a Lethal Septic Model open Access plus

Volume: 15   Issue: 7
Pp: 634-641
T. Zhao, H.B. Alam, B. Liu, R.T. Bronson, V.C. Nikolian, E. Wu, W. Chong and Y. Li
DOI:10.2174/156652401507150903185852

Activation of LINE-1 Retrotransposon Increases the Risk of Epithelial-Mesenchymal Transition and Metastasis in Epithelial Cancer open Access plus

Volume: 15   Issue: 7
Pp: 588-597
D. Rangasamy, N. Lenka, S. Ohms, J.E. Dahlstrom, A.C. Blackburn and P.G. Board
DOI:10.2174/1566524015666150831130827

Celastrol Inhibits Inflammatory Stimuli-Induced Neutrophil Extracellular Trap Formation open Access plus

Volume: 15   Issue: 4
Pp: 401-410
Y. Yu, C.D. Koehn, Y. Yue, S. Li, G.M. Thiele, M.P. Hearth-Holmes, T.R. Mikuls, J.R. O’Dell, L.W. Klassen, Z. Zhang and K. Su
DOI:10.2174/1566524015666150505160743

Improvement of Learning and Increase in Dopamine Level in the Frontal Cortex by Methylphenidate in Mice Lacking Dopamine Transporter open Access plus

Volume: 15   Issue: 3
Pp: 245-252
Y. Takamatsu, Y. Hagino, A. Sato, T. Takahashi, S.Y. Nagasawa, Y. Kubo, M. Mizuguchi, G.R. Uhl, I. Sora and K. Ikeda
DOI:10.2174/1566524015666150330144018

Neurobehavioral Differences Between Mice Receiving Distinct Neuregulin Variants as Neonates; Impact on Sensitivity to MK-801 open Access plus

Volume: 15   Issue: 3
Pp: 222-236
T. Kato, Y. Abe, S. Hirokawa, Y. Iwakura, M. Mizuno, H. Namba and H. Nawa
DOI:10.2174/1566524015666150330143300

Specific Roles of NMDA Receptor Subunits in Mental Disorders open Access plus

Volume: 15   Issue: 3
Pp: 193-205
H. Yamamoto, Y. Hagino, S. Kasai and K. Ikeda
DOI:10.2174/1566524015666150330142807

Imaging Genetics and Psychiatric Disorders open Access plus

Volume: 15   Issue: 2
Pp: 168-175
R. Hashimoto, K. Ohi, H. Yamamori, Y. Yasuda, M. Fujimoto, S. Umeda-Yano, Y. Watanabe, M. Fukunaga and M. Takeda
DOI:10.2174/1566524015666150303104159

Microendophenotypes of Psychiatric Disorders: Phenotypes of Psychiatric Disorders at the Level of Molecular Dynamics, Synapses, Neurons, and Neural Circuits open Access plus

Volume: 15   Issue: 2
Pp: 111-118
S. Kida and T. Kato
DOI:10.2174/1566524015666150303002128

Facioscapulohumeral Muscular Dystrophy: More Complex than it Appears open Access plus

Volume: 14   Issue: 8
Pp: 1052-1068
G. Ricci, M. Zatz and R. Tupler
DOI:10.2174/1566524014666141010155054

The Characteristics of Bax Inhibitor-1 and its Related Diseases open Access plus

Volume: 14   Issue: 5
Pp: 603-615
B. Li, R.K. Yadav, G.S. Jeong, H.-R. Kim and H.-J. Chae
DOI:10.2174/1566524014666140603101113

Regulation of RhoA Activity by Adhesion Molecules and Mechanotransduction open Access plus

Volume: 14   Issue: 2
Pp: 199-208
R.J. Marjoram, E.C. Lessey and K. Burridge
DOI:10.2174/1566524014666140128104541

Molecular Diagnosis in Autoimmune Skin Blistering Conditions open Access plus

Volume: 14   Issue: 1
Pp: 69-95
J.V. Otten, T. Hashimoto, M. Hertl, A.S. Payne and C. Sitaru
DOI:10.2174/15665240113136660079

The Multiple Aspects of Stroke and Stem Cell Therapy open Access plus

Volume: 13   Issue: 5
Pp: 821-831
B. Onteniente
DOI:10.2174/1566524011313050013

Single-Dose Microparticle Delivery of a Malaria Transmission- Blocking Vaccine Elicits a Long-Lasting Functional Antibody Response open Access plus

Volume: 13   Issue: 4
Pp: 479-487
R.R. Dinglasan, J.S. Armistead, J.F. Nyland, X. Jiang and H.Q. Mao
DOI:10.2174/1566524011313040002

Multiple Target-Specific Molecular Agents for Detection and Image Analysis of Breast Cancer Characteristics in Mice open Access plus

Volume: 13   Issue: 3
Pp: 446-458
S. Ke, W. Wang, X. Qiu, F. Zhang, J. T. Yustein, A. G. Cameron, S. Zhang, D. Yu, C. Zou, X. Gao, J. Lin, S. Yallampalli and M. Li
DOI:10.2174/1566524011313030014

Rock1 & 2 Perform Overlapping and Unique Roles in Angiogenesis and Angiosarcoma Tumor Progression open Access plus

Volume: 13   Issue: 1
Pp: 205-219
J. Montalvo, C. Spencer, A. Hackathorn, K. Masterjohn, A. Perkins, C. Doty, A. Arumugam, P. P. Ongusaha, R. Lakshmanaswamy, J. K. Liao, D. C. Mitchell and B. A. Bryan
DOI:10.2174/1566524011307010205

Podocyte Mitosis – A Catastrophe open Access plus

Volume: 13   Issue: 1
Pp: 13-23
L. Lasagni, E. Lazzeri, S. J. Shankland, H.-J. Anders and P. Romagnani
DOI:10.2174/1566524011307010013

Multiple Target-Specific Molecular Imaging Agents Detect Liver Cancer in a Preclinical Model open Access plus

Volume: 12   Issue: 8
Pp: 944-951
S. Ke, F. Zhang, W. Wang, X. Qiu, J. Lin, A. G. Cameron, C. Zou, X. Gao, C. Zou, V. F. Zhu and M. Li
DOI:10.2174/156652412802480952

Tissue Biomarkers for Prostate Cancer Radiation Therapy open Access plus

Volume: 12   Issue: 6
Pp: 772-787
P. T. Tran, R. K. Hales, J. Zeng, K. Aziz, T. Salih, R. P. Gajula, S. Chettiar, N. Gandhi, A. T. Wild, R. Kumar, J. M. Herman, D. Y. Song and T. L. DeWeese
DOI:10.2174/156652412800792589

Gene-Activation Mechanisms in the Regression of Atherosclerosis, Elimination of Diabetes Type 2, and Prevention of Dementia open Access plus

Volume: 11   Issue: 5
Pp: 391-400
P. V. Luoma
DOI:10.2174/156652411795976556

microRNAs in the Regulation of Adipogenesis and Obesity open Access plus

Volume: 11   Issue: 4
Pp: 304-316
R. A. McGregor and M. S. Choi
DOI:10.2174/156652411795677990

The Role of Immune and Inflammatory Mechanisms in ALS open Access plus

Volume: 11   Issue: 3
Pp: 246-254
P. A. McCombe and R. D. Henderson
DOI:10.2174/156652411795243450

Practical Aspects of microRNA Target Prediction open Access plus

Volume: 11   Issue: 2
Pp: 93-109
T. M. Witkos, E. Koscianska and W. J. Krzyzosiak
DOI:10.2174/156652411794859250

Monocyte and Macrophage Dysfunction as a Cause of HIV-1 Induced Dysfunction of Innate Immunity open Access plus

Volume: 10   Issue: 8
Pp: 727-740
P. Collini, M. Noursadeghi, I. Sabroe, R. F. Miller and D. H. Dockrell
DOI:10.2174/156652410793384141

From Nanotechnology to Nanomedicine: Applications to Cancer Research open Access plus

Volume: 10   Issue: 7
Pp: 640-652
R. Seigneuric, L. Markey, D. S.A. Nuyten, C. Dubernet, C. T.A. Evelo, E. Finot and C. Garrido
DOI:10.2174/156652410792630634

Molecular Mistletoe Therapy: Friend or Foe in Established Anti-Tumor Protocols? A Multicenter, Controlled, Retrospective Pharmaco-Epidemiological Study in Pancreas Cancer open Access plus

Volume: 10   Issue: 4
Pp: 430-439
H. Matthes, W.E. Friedel, P.R. Bock and K.S. Zanker
DOI:10.2174/156652410791317057

Prion Protein Misfolding open Access plus

Volume: 9   Issue: 7
Pp: 826-835
L. Kupfer, W. Hinrichs and M. H. Groschup
DOI:10.2174/156652409789105543

Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction open Access plus

Volume: 8   Issue: 6
Pp: 497-509
Helen M. Marriott, Timothy J. Mitchell and David H. Dockrell
DOI:10.2174/156652408785747924

Unique Biology of Mcl-1: Therapeutic Opportunities in Cancer open Access plus

Volume: 8   Issue: 2
Pp: 138-147
Gordon C. Shore and Matthew R. Warr
DOI:10.2174/156652408783769580

Insights from Animal Models on the Origins and Progression of Retinoblastoma open Access plus

Volume: 6   Issue: 7
Pp: 759-781
Marek Pacal and Rod Bremner
DOI:10.2174/1566524010606070759

Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis open Access plus

Volume: 6   Issue: 7
Pp: 739-748
James DeGregori and David G. Johnson
DOI:10.2174/1566524010606070739

Putting the Oncogenic and Tumor Suppressive Activities of E2F into Context open Access plus

Volume: 6   Issue: 7
Pp: 731-738
David G. Johnson and James DeGregori
DOI:10.2174/1566524010606070731