Abstract
Background and aims: Statins are an essential component of the therapeutic approach of patients with atherosclerotic disease. Statin use is also associated with improved peri-operative and long-term outcomes in these patients. We aimed to define the role of statin treatment in patients undergoing percutaneous revascularization procedures. Literature search method: We searched Medline for studies assessing the effect of statin treatment on percutaneous interventions. Literature search results: Early statin treatment is associated with improved outcomes in patients undergoing percutaneous coronary intervention procedures. Current evidence implies that statin treatment may also play a beneficial role in the management of patients undergoing percutaneous renal artery revascularization and endovascular abdominal aortic aneurysm repair, carotid angioplasty/stenting and endovascular peripheral arterial interventions. Conclusions: Preliminary data suggest that statins exert multiple beneficial actions in patients undergoing percutaneous interventions. Future randomized trials are expected to further evaluate the beneficial effects of statins in these procedures.
Keywords: Statins, percutaneous coronary intervention, peripheral arterial disease, endovascular abdominal aortic aneurysm repair, carotid angioplasty, carotid stenting
Current Drug Targets
Title: Statins Exert Multiple Beneficial Effects on Patients Undergoing Percutaneous Revascularization Procedures
Volume: 8 Issue: 8
Author(s): Kosmas I. Paraskevas, Vasilios G. Athyros, Despina D. Briana, Anna I. Kakafika, Asterios Karagiannis and Dimitri P. Mikhailidis
Affiliation:
Keywords: Statins, percutaneous coronary intervention, peripheral arterial disease, endovascular abdominal aortic aneurysm repair, carotid angioplasty, carotid stenting
Abstract: Background and aims: Statins are an essential component of the therapeutic approach of patients with atherosclerotic disease. Statin use is also associated with improved peri-operative and long-term outcomes in these patients. We aimed to define the role of statin treatment in patients undergoing percutaneous revascularization procedures. Literature search method: We searched Medline for studies assessing the effect of statin treatment on percutaneous interventions. Literature search results: Early statin treatment is associated with improved outcomes in patients undergoing percutaneous coronary intervention procedures. Current evidence implies that statin treatment may also play a beneficial role in the management of patients undergoing percutaneous renal artery revascularization and endovascular abdominal aortic aneurysm repair, carotid angioplasty/stenting and endovascular peripheral arterial interventions. Conclusions: Preliminary data suggest that statins exert multiple beneficial actions in patients undergoing percutaneous interventions. Future randomized trials are expected to further evaluate the beneficial effects of statins in these procedures.
Export Options
About this article
Cite this article as:
Kosmas I. Paraskevas , Vasilios G. Athyros , Despina D. Briana , Anna I. Kakafika , Asterios Karagiannis and Dimitri P. Mikhailidis , Statins Exert Multiple Beneficial Effects on Patients Undergoing Percutaneous Revascularization Procedures, Current Drug Targets 2007; 8 (8) . https://dx.doi.org/10.2174/138945007781386893
DOI https://dx.doi.org/10.2174/138945007781386893 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
Call for Papers in Thematic Issues
New drug therapy for eye diseases
Eyesight is one of the most critical senses, accounting for over 80% of our perceptions. Our quality of life might be significantly affected by eye disease, including glaucoma, diabetic retinopathy, dry eye, etc. Although the development of microinvasive ocular surgery reduces surgical complications and improves overall outcomes, medication therapy is ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Periodontal Bacteria Aggravate Chronic Renal Failure Induced by Subtotal Nephrectomy in Mice
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Targeting Chromatin Remodeling to Prevent Cardiovascular Disease in Diabetes
Current Pharmaceutical Biotechnology The Therapeutic Role of Taurine in Ischaemia-Reperfusion Injury
Current Pharmaceutical Design Pathophysiological Implications of Dipeptidyl Peptidases
Current Protein & Peptide Science Intracranial Aneurysms in Sickle Cell Disease
Current Neurovascular Research Use of Three-dimensional Printing in the Development of Optimal Cardiac CT Scanning Protocols
Current Medical Imaging Oxidative Stress and Lipid Peroxidation in Prolonged Users of Methamphetamine
Drug Metabolism Letters Mineralocorticoid Receptor Antagonism and Cardiac Remodeling in Ischemic Heart Failure
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Re-Wiring the Circuit: Mitochondria as a Pharmacological Target in Liver Disease
Current Medicinal Chemistry Impact of Tracer Retention Levels on Visual Analysis of Cerebral [<sup>18</sup>F]- Florbetaben Pet Images
Current Radiopharmaceuticals Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer’s Disease
Current Alzheimer Research Past and Present Behçet’s Disease Animal Models
Current Drug Targets Therapeutic Hypothermia in Brain Injuries and Related Diseases
Recent Patents on Inflammation & Allergy Drug Discovery Normal Bicaudate Index by Aging
Current Medical Imaging Preventing Death from Abdominal Aortic Aneurysm Rupture
Vascular Disease Prevention (Discontinued) Recent Patents on Electrospun Biomedical Nanostructures: An Overview
Recent Patents on Biomedical Engineering (Discontinued) Patient-Specific Modeling and Multi-Scale Blood Simulation for Computational Hemodynamic Study on the Human Cerebrovascular System
Current Pharmaceutical Biotechnology Hemodialysis Membranes for Acute and Chronic Renal Insufficiency
Current Neurovascular Research Experimental Models of Abdominal Aortic Aneurysms: An Overview
Current Pharmaceutical Design Radiological Assessment of Giant Cell Tumour of Bone in the Sacrum: From Diagnosis to Treatment Response Evaluation
Current Medical Imaging