Current Drug Metabolism

Editor-in-Chief:

Michael Sinz

Bristol Myers Squibb

Princeton, NJ

USA

 

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Expression and Function of Cytochrome P450 in Brain Drug Metabolism

Volume:8   Issue:4
Pp: 297-306
R. P. Meyer, M. Gehlhaus, R. Knoth and B. Volk
DOI: 10.2174/138920007780655478

CYP-Mediated Clozapine Interactions: How Predictable Are They?

Volume:8   Issue:4
Pp: 307-313
Manoranjenni Chetty and Michael Murray
DOI: 10.2174/138920007780655469

The Non-ABC Drug Transporter RLIP76 (RALBP-1) Plays a Major Role in the Mechanisms of Drug Resistance

Volume:8   Issue:4
Pp: 315-323
Yogesh C. Awasthi, Rajendra Sharma, Sushma Yadav, Seema Dwivedi, Abha Sharma and Sanjay Awasthi
DOI: 10.2174/138920007780655414

Role of P-Glycoprotein in the Intestinal Absorption of Tanshinone IIA, a Major Active Ingredient in the Root of Salvia miltiorrhiza Bunge

Volume:8   Issue:4
Pp: 325-340
Xi-Yong Yu, Shu-Guang Lin, Zhi-Wei Zhou, Xiao Chen, Jun Liang, Pei-Qing Liu, Wei Duan, Balram Chowbay, Jing-Yuan Wen, Chun-Guang Li and Shu-Feng Zhou
DOI: 10.2174/138920007780655450

Evaluation of Drug-Transporter Interactions Using In Vitro and In Vivo Models

Volume:8   Issue:4
Pp: 341-363
Cindy Q. Xia, Mark N. Milton and Liang-Shang Gan
DOI: 10.2174/138920007780655423

Transport of Cryptotanshinone, a Major Active Triterpenoid in Salvia Miltiorrhiza Bunge Widely Used in the Treatment of Stroke and Alzheimers Disease, Across the Blood-Brain Barrier

Volume:8   Issue:4
Pp: 365-377
Xi-Yong Yu, Shu-Guang Lin, Xiao Chen, Zhi-Wei Zhou, Jun Liang, Wei Duan, Balram Chowbay, Jing-Yuan Wen, Eli Chan, Jie Cao, Chun-Guang Li and Shu-Feng Zhou
DOI: 10.2174/138920007780655441

A Pharmacokinetic Interaction Between Clarithromycin and Sirolimus in Kidney Transplant Recipient

Volume:8   Issue:4
Pp: 379-381
Domenico Capone, Giuseppe Palmiero, Antonio Gentile, Vincenzo Basile, Stefano Federico, Massimo Sabbatini, Maria Potenza, Anna Perfetti, Maria Pieri and Giovanni Tarantino
DOI: 10.2174/138920007780655405

Synergistic Cytotoxic Activity of Recombinant TRAIL Plus the Non-Genotoxic Activator of the p53 Pathway Nutlin-3 in Acute Myeloid Leukemia Cells

Volume:8   Issue:4
Pp: 395-403
Paola Secchiero, Carlotta Zerbinati, Maria Grazia di Iasio, Elisabetta Melloni, Mario Tiribelli, Vittorio Grill and Giorgio Zauli
DOI: 10.2174/138920007780655432