Current Drug Metabolism

Editor-in-Chief:

Michael Sinz

Bristol Myers Squibb

Princeton, NJ

USA

 

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Editorial: [Hot Topics: Metabolism and Drug-Drug Interaction Potential of Biotherapeutics] free to download

Volume:13   Issue:7
Pp: 881-881
Albert P. Li
DOI: 10.2174/138920012802138697

Catabolic Fate and Pharmacokinetic Characterization of Trastuzumab Emtansine (T-DM1): an Emphasis on Preclinical and Clinical Catabolism

Volume:13   Issue:7
Pp: 901-910
Ben-Quan Shen, Daniela Bumbaca, Ola Saad, Qin Yue, Cinthia V. Pastuskovas, S. Cyrus Khojasteh, Jay Tibbitts, Surinder Kaur, Bei Wang, Yu-Waye Chu, Patricia M. LoRusso and Sandhya Girish
DOI: 10.2174/138920012802138598

Drug Interaction Potential of Trastuzumab Emtansine (T-DM1) Combined with Pertuzumab in Patients With HER2-Positive Metastatic Breast Cancer

Volume:13   Issue:7
Pp: 911-922
Dan Lu, Howard A. Burris III, Bei Wang, E. Claire Dees, Javier Cortes, Amita Joshi, Manish Gupta, Joo-Hee Yi, Yu-Waye Chu, Ted Shih, Liang Fang and Sandhya Girish
DOI: 10.2174/138920012802138688

De-Risking Bio-therapeutics for Possible Drug Interactions Using Cryopreserved Human Hepatocytes

Volume:13   Issue:7
Pp: 923-929
Shannon Dallas, Carlo Sensenhauser, Ameesha Batheja, Monica Singer, Maria Markowska, Cindy Zakszewski, Rao N.V.S. Mamidi, Michael McMillia, Chao Han, Honghui Zhou and Jose Silva
DOI: 10.2174/138920012802138589

Effects of Interleukin 1β (IL-1β) and IL-1β/Interleukin 6 (IL-6) Combinations on Drug Metabolizing Enzymes in Human Hepatocyte Culture open access plus

Volume:13   Issue:7
Pp: 930-937
Leslie J. Dickmann, Sonal K. Patel, Larry C. Wienkers and J. Greg Slatter
DOI: 10.2174/138920012802138642

Animal Models for Evaluation of Drug-Drug Interaction Potential of Biotherapeutics open access plus

Volume:13   Issue:7
Pp: 947-950
Eugenia Kraynov, Martin E. Dowty, Odette Odette A. Fahmi and Owen Fields
DOI: 10.2174/138920012802138705



Editorial: [SNPs of Drug Metabolic Enzymes and Personalized Medicine Part II] free to download

Volume:13   Issue:7
Pp: 951-951
Dong-Qing Wei and Qi Chen
DOI: 10.2174/138920012802138651

The SmartAmp Method: Rapid Detection of SNPs in Thiopurine S-Methyltransferase and ABC Transporters ABCC4 and ABCG2

Volume:13   Issue:7
Pp: 968-977
Wanping Aw, Alexander Lezhava, Akira Andoh, Hiroshi Tanaka, Yoshihide Hayashizaki and Toshihisa Ishikawa
DOI: 10.2174/138920012802138543

SNP Web Resources and Their Potential Applications in Personalized Medicine

Volume:13   Issue:7
Pp: 978-990
Jingbo Wang, Grace S.Y. Pang, Samuel S. Chong and Caroline G.L. Lee
DOI: 10.2174/138920012802138552

The Importance of Integrating SNP and Cheminformatics Resources to Pharmacogenomics

Volume:13   Issue:7
Pp: 991-999
Hsueh-Wei Chang, Li-Yeh Chuang, Ming-Tz Tsai and Cheng-Hong Yang
DOI: 10.2174/138920012802138679

Personalized Medicine: Potential, Barriers and Contemporary Issues

Volume:13   Issue:7
Pp: 1000-1006
Michael J. Sorich and Ross A. McKinnon
DOI: 10.2174/138920012802138615

Detection of EGFR Somatic Mutations in Non-Small Cell Lung Cancer (NSCLC) Using a Novel Mutant-Enriched Liquidchip (MEL) Technology

Volume:13   Issue:7
Pp: 1007-1011
Li Zhang, Huiyi Yang, Yanwei Zhao, Wenchao Liu, Shiyang Wu, Jiaying He, Xiaodi Luo, Zeyao Zhu, Jiasen Xu, Qinghua Zhou and Lifen Ren-Heidenreich
DOI: 10.2174/138920012802138660

Prediction and Functional Analysis of Single Nucleotide Polymorphisms

Volume:13   Issue:7
Pp: 1012-1023
Li Li, Qi Chen and Dong-Qing Wei
DOI: 10.2174/138920012802138561

Negatively Cooperative Binding Properties of Human Cytochrome P450 2E1 with Monocyclic Substrates

Volume:13   Issue:7
Pp: 1024-1031
Jie Ping, Ya-Jun Wang, Jing-Fang Wang, Xuan Li, Yi-Xue Li and Pei Hao
DOI: 10.2174/138920012802138606