Current Drug Therapy

Optimization and Quality by Design Approach for Piroxicam Fast Dissolving Tablet Formulations Using Box-Behnken Design

Volume: 15   Issue: 2
Pp: 152-165
Harekrishna Roy*, Sisir Nandi, Ungarala Pavani, Uppuluri Lakshmi, Tamma Saicharan Reddy and Damarla Venkata Sri Gayatri
DOI: 10.2174/1574885514666190409102614

Development and Characterization of Solid Dispersion System for Enhancing the Solubility and Dissolution Rate of Dietary Capsaicin

Volume: 15   Issue: 2
Pp: 143-151
Sumit Bera, Subhasis Maity, Balaram Ghosh, Animesh Ghosh and Tapan K. Giri*
DOI: 10.2174/1574885514666190724143351

An Updated Overview of The Complex Clinical Spectrum of Tourette Syndrome

Volume: 15   Issue: 2
Pp: 86-91
Natan Gadoth*
DOI: 10.2174/1574885514666191120143747

Drug and Non-drug Treatment of Tourette Syndrome

Volume: 15   Issue: 2
Pp: 132-142
Nathanel Zelnik*
DOI: 10.2174/1574885514666191121141923

Sleep and Sleep Disorders in Tourette Syndrome: What is Known and What is Still Unknown open access plus

Volume: 15   Issue: 2
Pp: 124-131
Arie Oksenberg*
DOI: 10.2174/1574885514666191121142555

The Pathophysiology of Tics; An Evolving Story

Volume: 15   Issue: 2
Pp: 92-123
Harvey S. Singer* and Farhan Augustine
DOI: 10.2174/1574885514666191121143930

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Volume: 15   Issue: 2
Pp: 85-85
Natan Gadoth
DOI: 10.2174/157488551502200303113311

Investigation of the Role of the Alkalizing Agent in Sodium Alginate Liquid Anti-reflux Suspension

Volume: 15   Issue: 1
Pp: 53-60
Sangmesh Torne, A. Sheela* and N.C. Sarada
DOI: 10.2174/1574885514666190103140951

Optimization of Brinzolamide Loaded Microemulsion using Formulation by Design Approach: Characterization and In-vitro Evaluation

Volume: 15   Issue: 1
Pp: 37-52
Riyaz Gohil, Asha Patel*, Tosha Pandya and Abhay Dharamsi
DOI: 10.2174/1574885514666190104115802

Review on Preclinical and Clinical Evidence of Food (Beverages, Fruits and Vegetables) and Drug Interactions: Mechanism and Safety

Volume: 15   Issue: 1
Pp: 12-27
Yogesh C. Yadav*, Kamla Pathak and Devender Pathak
DOI: 10.2174/1574885514666190126141424

Formulation and in vitro Evaluation of Hesperidin-Phospholipid Complex and its Antioxidant Potential

Volume: 15   Issue: 1
Pp: 28-36
Bhupen Kalita* and Bhargab Nath Patwary
DOI: 10.2174/1574885514666190226155933

Effects of Coenzyme Q10 Supplementation on Serum Adiponectin Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Volume: 15   Issue: 1
Pp: 3-11
Ali Nazary-Vannani, Ehsan Ghaedi, Shekoufeh Salamat, Afsaneh Sayyaf, Hamed K. Varkaneh, Hamed Mohammadi and Mahmoud Djalali*
DOI: 10.2174/1574885514666190308162322

Prevalence of Major Cardiac Events of Anthracycline-Induced Cardiotoxicity in Southwestern Iran: Different Response Patterns to Cumulative Dose

Volume: 15   Issue: 1
Pp: 78-84
Mahsa Behrouzian, Babak Najibi, Sabahat Haghi, Chehreh Mahdavi, Kaveh Jaseb* and Ehsan Ghaedi*
DOI: 10.2174/1574885514666190311145607

Polymeric Nanoparticles: A Promising Tool to Enhance the Solubility of Poorly Water Soluble Drug

Volume: 15   Issue: 1
Pp: 67-77
Nirmal M. Kasekar*, Sarabjit Singh, K.R. Jadhav and V.J. Kadam
DOI: 10.2174/1574885514666190610125127

Randomised Study Comparing the use of Propofol Versus Dexmedetomidine as a Sedative Agent for Patients Presenting for Lower Gastrointestinal Endoscopy

Volume: 15   Issue: 1
Pp: 61-66
Sameh A. Ahmed, Nehad Hawash, Fatma H. Rizk, Mahmoud Elkadeem, Mohamed Elbahnasawy and Sherief Abd-Elsalam*
DOI: 10.2174/1574885514666190904161705

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Volume: 15   Issue: 1
Pp: 1-1
Imran Ali
DOI: 10.2174/157488551501200114144207

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Volume: 15   Issue: 1
Pp: 2-2
Stefano Palomba
DOI: 10.2174/157488551501200114144349

Bilosomes: Superior Vesicular Carriers open access plus

Volume: 15   Issue:
Pp: 1-9
Pradnya Palekar - Shanbhag *, Supriya Lande, Riya Chandra and Drushti Rane
DOI: 10.2174/1574885514666190917145510

Hypoglycemic Hemiparesis Masquerading As Ischemic Stroke: When Guideline Fails

Volume: 15   Issue:
Pp: 1-3
Dhruvkumar M. Patel, Mukundkumar V. Patel *, Jayanti K. Gurumukhani, Maitri M. Patel, Himal J. Mahadevia and Ritesh A. Gajjar
DOI: 10.2174/1574885515666191227155624

The Effect of Treatment and Bone Metabolic Factors on Fracture Incidence in Patients with Thalassemia-Induced Osteoporosis: An Observational Study open access plus

Volume: 15   Issue:
Pp: 1-8
Athanasios N. Tsartsalis*, George I. Lambrou, Evgenia Vlachou, Athanasia Samartzi, George P. Chrousos, Christina Kanaka-Gantenbein and Antonis Kattamis
DOI: 10.2174/1574885515666200106110602

Evaluation of the Drug Utilization Pattern of Pre and Post Operative Medicines used in Surgical Department: A Prospective Observational Study

Volume: 15   Issue:
Pp: 1-7
Shikha Sharma and Anoop Kumar*
DOI: 10.2174/1574885515666200106111129

Allopurinol Loaded Transferosomes for the Alleviation of Symptomatic After-effects of Gout: An Account of Pharmaceutical Implications open access plus

Volume: 15   Issue:
Pp: 1-16
Ruchi Tiwari*, Gaurav Tiwari and Rachna Singh
DOI: 10.2174/1574885515666200120124214

Application of D-optimal Mixture Design for Development and Optimization of Olmesartan Medoxomil Loaded SMEDDS open access plus

Volume: 15   Issue:
Pp: 1-13
Navdeep Gahlawat, Ravinder Verma and Deepak Kaushik *
DOI: 10.2174/1574885515666200212094039

Synergy effects of metformin and berberine on glyoxal-induced carbonyl stress in isolated rat liver mitochondria

Volume: 15   Issue:
Pp: 1-1
Mohsen Rezaei, Heibatullah Kalantari, Saeed Mehrzadi and Mehdi Goudarzi*
DOI: 10.2174/1574885515666200214122055

In-vitro Comparative Study of Different Brands of Metoclopramide Hydrochloride Tablets Marketed in Saudi Arabia

Volume: 15   Issue:
Pp: 1-1
Umme Hani*, Mohammed Rahmatulla, Ahaya Alhamhoom, Riyaz Osmani and Yasmeen Begum
DOI: 10.2174/1574885515666200305101840

Formulation Development and Characterization of controlled release core in cup matrix tablets of venlafaxine HCl

Volume: 15   Issue:
Pp: 1-26
Balaji Maddiboyina, Vikas Jhawat*, Gandhi Sivaraman, Om Prakash Sunnapu, Ramya Krishna Nakkala, Mudavath Hanuma Naik and Monika Gulia
DOI: 10.2174/1574885515666200331104440

Development & Pharmaceutical Characterization of Isoniazid Loaded Solid Lipid Nanoparticle Drug Delivery Approach

Volume: 14   Issue: 3
Pp: 228-238
Swatantra Kumar Singh Kushwaha*, Awani Kumar Rai and Heena Parveen
DOI: 10.2174/1574885514666190103114200

Formulation of Dry Powder Inhaler of Anti-tuberculous Drugs Using Spray Drying Technique and Optimization Using 23 Level Factorial Design Approach

Volume: 14   Issue: 3
Pp: 239-260
Vaishali Thakkar*, Ekta Pandey, Tosha Pandya, Purvi Shah, Asha Patel, Roma Trivedi, Mukesh Gohel, Lalji Baldaniya and Tejal Gandhi
DOI: 10.2174/1574885514666190104114209

Analysis of Safety Outcomes in Chronic Hepatitis C Patients using Interferon-free Treatment: A Systematic Review of Case Reports

Volume: 14   Issue: 3
Pp: 210-219
Vinicius Lins Ferreira*, Leticia Paula Leonart, Ana Maria Della Rocca and Roberto Pontarolo
DOI: 10.2174/1574885514666190130162547

Drug/Vehicle Impacts and Formulation Centered Stratagems for Enhanced Transdermal Drug Permeation, Controlled Release and Safety: Unparalleled Past and Recent Innovations-An Overview

Volume: 14   Issue: 3
Pp: 192-209
Balamurugan Manickam*, Rajesh Sreedharan and Kumarappan Chidambaram
DOI: 10.2174/1574885514666190212113754

Equibiotic-GI Consumption Improves Intestinal Microbiota in Subjects with Functional Dyspepsia

Volume: 14   Issue: 3
Pp: 220-227
Berenice Palacios-González*, Noemí Meraz-Cruz, Fernanda Valdez-Palomares and Rafael Nambo-Venegas
DOI: 10.2174/1574885514666190212114412

Ramelteon in the Treatment of Delirium: New Perspectives from Reported Findings and a Case Observation

Volume: 14   Issue: 3
Pp: 184-191
Deborah L. Sanchez, Adam J. Fusick, William B. Hudson, Jourdan E. Schmitz, Maria C. Catalano and Glenn Catalano*
DOI: 10.2174/1574885514666190308161421

A Study of Prescription Pattern and Compliance of Anti-hypertensives with the Treatment Guidelines in Aseer Region; Saudi Arabia open access plus

Volume: 14   Issue: 3
Pp: 261-266
Ayesha Siddiqua*, Afaf Alshehri, Amal M. Alahmari, Rawan A. Alshehri and Somayh S. Badawy
DOI: 10.2174/1574885514666190424155014

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Volume: 14   Issue: 3
Pp: 183-183
Yanmin Zhang
DOI: 10.2174/157488551403191023124455

ACKNOWLEDGEMENTS TO REVIEWERS promotion: free to download

Volume: 14   Issue: 3
Pp: 267-267

DOI: 10.2174/157488551403191023150841

Strategically Placed Trifluoromethyl Substituent in the Realm of Antitubercular Drug Design

Volume: 14   Issue: 2
Pp: 114-123
Sidhartha S. Kar and Cinu A. Thomas*
DOI: 10.2174/1574885513666180906101732

Role of Unani Medicines in Cancer Control and Management

Volume: 14   Issue: 2
Pp: 92-113
Imran Ali*, Mohd. Suhail, Mohd. Farooq Naqshbandi, Mohd. Fazil, Bilal Ahmad and Ahmad Sayeed
DOI: 10.2174/1574885513666180907103659

Comparison of Mono-dopaminergic and Multi-target Pharmacotherapies in Primary Parkinson Syndrome and Assessment Tools to Evaluate Motor and Non-motor Symptoms

Volume: 14   Issue: 2
Pp: 124-134
Felix-Martin Werner* and Rafael Coveñas
DOI: 10.2174/1574885513666181115104137

Drug in Adhesive Transdermal Formulation of Valsartan and Nifedipine: Pharmacokinetics and Pharmacodynamics in Rats

Volume: 14   Issue: 2
Pp: 153-167
Jatin Sood, Bharti Sapra and Ashok K. Tiwary*
DOI: 10.2174/1574885514666181120114635

Systematic Scrutinisation of Vital Factors for Fabrication and Evaluation of PGS-MCC Based Drug Loaded Pellets by Extrusion Spheronization Technique

Volume: 14   Issue: 2
Pp: 168-182
Hardik Rana, Vaishali Thakkar*, Kalpana Mudgal, Mukesh Gohel, Lalji Baldania, Mansi Dholakia and Tejal Gandhi
DOI: 10.2174/1574885514666181123152641

Local Drug Delivery Based Treatment Approaches for Effective Management of Periodontitis

Volume: 14   Issue: 2
Pp: 135-152
Geeta Aggarwal, Sonia Verma, Madhu Gupta and Manju Nagpal*
DOI: 10.2174/1574885514666190103112855

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Volume: 14   Issue: 2
Pp: 91-91
Monica Mita
DOI: 10.2174/157488551402190802113751

Comparison of Valvulopathy Risk with Lorcaserin and Phenterminetopiramate for Weight Loss

Volume: 14   Issue: 1
Pp: 74-78
Michael Guo, Mahyar Etminan* and Bruce Carleton
DOI: 10.2174/1574885513666180503141557

Molecular Docking Study for Analyzing the Inhibitory Effect of Anti-inflammatory Plant Compound Against Tumour Necrosis Factor (TNF-α)

Volume: 14   Issue: 1
Pp: 85-90
Sagarika Biswas*
DOI: 10.2174/1574885513666180503145352

An in silico Approach to Identify Potential NDM-1 Inhibitors to Fight Multidrug Resistant Superbugs

Volume: 14   Issue: 1
Pp: 79-84
Seema Barman, Bonashree Phukan, Partha Sarathi Borah, Minakshi Puzari, Mohan Sharma and Pankaj Chetia*
DOI: 10.2174/1574885513666180514161513

Effect of Myricetin on the Loss of Dopaminergic Neurons in the Transgenic Drosophila Model of Parkinson’s Disease

Volume: 14   Issue: 1
Pp: 58-64
Gulshan Ara, Mohammad Afzal, Smita Jyoti, Falaq Naz, Rahul and Yasir Hasan Siddique*
DOI: 10.2174/1574885513666180529114546

Bio-analytical Assay Methods used in Therapeutic Drug Monitoring of Antiretroviral Drugs-A Review

Volume: 14   Issue: 1
Pp: 16-57
Nitin B. Charbe*, Flavia C. Zacconi, Nikhil Amnerkar, B. Ramesh, Murtaza M. Tambuwala and Emilio Clementi
DOI: 10.2174/1574885514666181217125550

Preparation and Characterization of Freeze-dried Liposomes Loaded with Amphotericin B

Volume: 14   Issue: 1
Pp: 65-73
Tran Thi Hai Yen, Le Nho Dan, Le Hoang Duc, Bui Thanh Tung and Pham Thi Minh Hue*
DOI: 10.2174/1574885514666181217130259

Biomimetic Approaches for Targeted Nanomedicine: Current Status and Future Perspectives

Volume: 14   Issue: 1
Pp: 3-15
Jaya Agnihotri, Priyanka Maurya, Shobhna Singh and Shubhini A. Saraf*
DOI: 10.2174/1574885514666181220092721

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Volume: 14   Issue: 1
Pp: 1-1
Emmanuel A. Theodorakis
DOI: 10.2174/157488551401190222095013

Preface promotion: free to download

Volume: 14   Issue: 1
Pp: 2-2
Stefano Palomba
DOI: 10.2174/157488551401190222095650

PCR: An Effective, Faster and Relevant Method for the Detection of Clinical Isolates of Candida albicans

Volume: 14   Issue:
Pp: 1-3
Kamal Uddin Zaidi, Abin Mani*, Richa Parmar and Vijay Thawani
DOI: 10.2174/1574885514666190409104833

Oleic Acid Vesicles for Transdermal Delivery of Propranolol Hydrochloride: Development and Characterization open access plus

Volume: 14   Issue:
Pp: 1-13
Lalit Kumar and Puneet Utreja*
DOI: 10.2174/1574885514666190722164119

The Effect of Casein Kinase 2 Inhibition on three Leukemic Cell Lines

Volume: 14   Issue:
Pp: 1-9
Luka Horvat, Mariastefania Antica and Maja Matulić*
DOI: 10.2174/1574885514666190724111509

Network-Pharmacology and DFT Based Approach Towards Identification of Leads from Homalomena aromatica for Multi- Target In-Silico Screening on Entamoeba histolytica Proteins

Volume: 14   Issue:
Pp: 1-14
Ashis Kumar Goswami , Neelutpal Gogoi, Bhaskar Jyoti Gogoi and Hemanta Kumar Sharma*
DOI: 10.2174/1574885514666190801102336

Treatment with Cinacalcet in Hemodialysis Patients with Severe Secondary Hyperparathyroidism, Influences Bone Mineral Metabolism and Anemia Parameters

Volume: 14   Issue:
Pp: 1-17
Maria Aktsiali, Theodora Papachrysanthou , Ioannis Griveas, Christos Andriopoulos, Panagiotis Sitaras, Ioannis K. Triantafyllopoulos and George I. Lambrou*
DOI: 10.2174/1574885514666190802144629

Pathophysiology and Management of Atopic Dermatitis: A Laconic Review open access plus

Volume: 14   Issue:
Pp: 1-20
Pravin Kumar*, Mahendra Singh Ashawat and Dinesh Kumar Sharmaa
DOI: 10.2174/1574885514666190828152316

Azelaic Acid: A Promising Agent for Dermatological Applications

Volume: 14   Issue:
Pp: 1-13
Anil Kumar, Rekha Rao* and Poonam Yadav
DOI: 10.2174/1574885514666190904160228

Exploring of Taguchi Design in the Optimization of Brinzolamide and Timolol Maleate Ophthalmic in-situ Gel used in Treatment of Glaucoma open access plus

Volume: 14   Issue:
Pp: 1-19
Purvi Shah, Vaishali Thakkar*, Vishvas Anjana, Jenee Christiana, Roma Trivedi , Kalpana Patel, Mukesh Gohel and Tejal Gandhi
DOI: 10.2174/1574885514666190916151506

Formulation and Characterization of Solid Dispersion Containing Capsaicin for the Treatment of Diabetes

Volume: 14   Issue:
Pp: 1-7
Tapan Kumar Giri*, Payel Roy and Subhasis Maity
DOI: 10.2174/1574885514666190916152432

Prevention and Therapy of Prostate Cancer: An Update on Alternatives for Treatment and Future Perspectives

Volume: 14   Issue:
Pp: 1-12
Fernanda Majolo*, Bruna Caye, Stefani Stoll, Juliano Leipelt, Ana Abujamra and Márcia Inês Goettert
DOI: 10.2174/1574885514666190917150635

In Silico Docking, ADMET and QSAR Study of few Antimalarial Phytoconstituents as Inhibitors of Plasmepsin II of P. falciparum Against Malaria

Volume: 14   Issue:
Pp: 1-10
Syeda Sabiha*, Pankaj Chetia and Devid Kardong
DOI: 10.2174/1574885514666190923112738

Effect of Canagliflozin, an SGLT2 Inhibitor, in Comparison with Atorvastatin on Dexamethasone-Induced Hepatic Steatosis in Albino Rats open access plus

Volume: 14   Issue:
Pp: 1-9
Eman I Ahmed*, Amany M Shaaban and Abdel Karim M Abdel Latif
DOI: 10.2174/1574885514666191007094424

Current Strategies and Future Perspective for the Effective Treatment of Diabetic Retinopathy

Volume: 14   Issue:
Pp: 1-14
Deep Shikha Sharma, Sheetu Wadhwa*, Sachin Kumar Singh, Divya Thakur, Arya K.R and Rubiya Khursheed
DOI: 10.2174/1574885514666191007101007

Traditional Herbal Medicines, Newer Herbs and Other Novel Approaches Integrated in Herbal Medicine for Atopic Dermatitis-A Narrative Review

Volume: 14   Issue:
Pp: 1-15
Pravin Kumar*, Mahendra Singh Ashawat and Dinesh Kumar Sharma
DOI: 10.2174/1574885514666191018165209

Development of Cinnarizine Microballoons by Sequential Optimization and In Vivo Imaging by Gamma Scintigraphy

Volume: 14   Issue:
Pp: 1-12
Bijaya Ghosh*, Arka Chatterjee, Moumita Das Kirtania and Sankha Chattopadhyay
DOI: 10.2174/1574885514666191119105908

Celecoxib A Selective COX-2 Inhibitor Mitigates Fibrosis but not Pneumonitis Following Lung Irradiation: A Histopathological Study open access plus

Volume: 14   Issue:
Pp: 1-7
Rasoul Azmoonfar, Peyman Amini, Hana Saffar, Elahe Motevaseli, Ehsan Khodamoradi, Dheyauldeen Shabeeb, Ahmed Eleojo Musa and Masoud Najafi*
DOI: 10.2174/1574885514666191119124739

Beneficial Effects of Melatonin and Atorvastatin on Retinopathy in Streptozocin-induced Diabetic Rats open access plus

Volume: 14   Issue:
Pp: 1-8
Mansoor Shahriari, Saeed Mehrzadi, Masood Naseripour, Iman Fatemi, Azam Hosseinzadeh, Mozhgan Rezaei Kanavi and Habib Ghaznavi*
DOI: 10.2174/1574885514666191204104925

Spectral Investigations, Molecular Interactions and Electrochemical Studies of (2R)-(-) 2-(2, 6-dimethylphenylaminocarbonyl)-1-methyl piperidinium chloride open access plus

Volume: 14   Issue:
Pp: 1-11
J. Deva Anban, J. Sharmi Kumar, C. James and Sayantan Pradhan*
DOI: 10.2174/1574885514666191204150832

2', 4'-dihydroxy-3, 4-methylenedioxychalcone Activate Mitochondrial Apoptosis of Ehrlich Ascites Carcinoma Cells

Volume: 14   Issue:
Pp: 1-14
Jahan Ara Khanam, Alfred King-Yin Lam, Mahbuba Khatun, Farhadul Islam*, Vinod Gopalan, Md. Motiar Rahman, Natasha Zuberi, Laboni Khatun, Md. Abdur Rakiba and Md. Azizul Islam
DOI: 10.2174/1574885514666191211122437

High Throughput Screening Based Highly Potent Sulfonylbenzamide Anti-diabetic Drug

Volume: 13   Issue: 2
Pp: 162-173
Sayantan Pradhan and Chittaranjan Sinha*
DOI: 10.2174/1574885512666171023154352

Treatment of Atopic Dermatitis: Current Status and Future Prospects

Volume: 13   Issue: 2
Pp: 108-129
Kusha Sharma, Bharti Sapra and Neena Bedi*
DOI: 10.2174/1574885512666171123165636

Molecular Modeling of Benzimidazole Derivatives: A Promising Series of GluN2B Selective NMDA Receptor Antagonists

Volume: 13   Issue: 2
Pp: 152-161
Marcos Vinicius Santana, Helena Carla Castro and Paula Alvarez Abreu*
DOI: 10.2174/1574885512666171128145952