Current Drug Targets


Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556


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Most Accessed Articles

Cytochrome P450 Structure, Function and Clinical Significance: A Review promotion: free to download

Volume: 19   Issue: 1
Pp: 38-54
Palrasu Manikandan and Siddavaram Nagini*
DOI: 10.2174/1389450118666170125144557

PARP Inhibitor Drugs in the Treatment of Breast, Ovarian, Prostate and Pancreatic Cancers: An Update of Clinical Trials promotion: free to download

Volume: 19   Issue: 1
Pp: 21-37
Dalia Kamel*, Christopher Gray, Jagdeep Singh Walia and Vikaash Kumar*
DOI: 10.2174/1389450118666170711151518

Bromodomain-Containing Protein 4: A Druggable Target

Volume: 20   Issue: 15
Pp: 1517-1536
Yingying Shi, Jingwen Liu, Yuanyuan Zhao, Jiaoxian Cao, Yiming Li* and Fujiang Guo*
DOI: 10.2174/1574885514666190618113519

Absolute Blood Eosinophil Counts to Guide Inhaled Corticosteroids Therapy Among Patients with COPD: Systematic Review and Meta-analysis

Volume: 20   Issue: 16
Pp: 1670-1679
Olorunfemi A. Oshagbemi, Jephthah O. Odiba, Abraham Daniel and Ismaeel Yunusa*
DOI: 10.2174/1389450120666190808141625

Recent Progress in Gene Therapy and Other Targeted Therapeutic Approaches for Beta Thalassemia

Volume: 20   Issue: 16
Pp: 1603-1623
Eman M. Hamed, Mohamed Hussein Meabed, Usama Farghaly Aly and Raghda R.S. Hussein*
DOI: 10.2174/1389450120666190726155733

Advances in the Discovery of PDE10A Inhibitors for CNS-Related Disorders. Part 2: Focus on Schizophrenia

Volume: 20   Issue: 16
Pp: 1652-1669
Artur Świerczek, Agnieszka Jankowska, Grażyna Chłoń-Rzepa, Maciej Pawłowski and Elżbieta Wyska*
DOI: 10.2174/1389450120666190801114210

Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis open access plus

Volume: 20   Issue: 16
Pp: 1695-1701
Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J. Castellino
DOI: 10.2174/1389450120666190715102510

Pre-operative Exposure to Ustekinumab: A Risk Factor for Postoperative Complications in Crohn's Disease (CD)?

Volume: 20   Issue: 13
Pp: 1369-1372
Hang Hock Shim*, Christopher Ma, Paulo Gustavo Kotze and Remo Panaccione
DOI: 10.2174/1389450120666190515094435

Steroids and Postoperative Complications in IBD

Volume: 20   Issue: 13
Pp: 1323-1326
Antonio López-Sanromán*
DOI: 10.2174/1389450120666190320122939

Significance and Mechanisms of P-glycoprotein in Central Nervous System Diseases

Volume: 20   Issue: 11
Pp: 1141-1155
Liangliang Huang, Binbin Li, Xiang Li, Ge Liu, Rui Liu, Jia Guo, Baohui Xu, Yunman Li* and Weirong Fang*
DOI: 10.2174/1389450120666190308144448