Current Drug Targets


Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556


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Most Accessed Articles

Cytochrome P450 Structure, Function and Clinical Significance: A Review promotion: free to download

Volume: 19   Issue: 1
Pp: 38-54
Palrasu Manikandan and Siddavaram Nagini*
DOI: 10.2174/1389450118666170125144557

PARP Inhibitor Drugs in the Treatment of Breast, Ovarian, Prostate and Pancreatic Cancers: An Update of Clinical Trials promotion: free to download

Volume: 19   Issue: 1
Pp: 21-37
Dalia Kamel*, Christopher Gray, Jagdeep Singh Walia and Vikaash Kumar*
DOI: 10.2174/1389450118666170711151518

Recent Advancements in Diagnosis and Therapy of Liver Cirrhosis

Volume: 17   Issue: 15
Pp: 1804-1817
Roberto Giulio Romanelli and Cristina Stasi
DOI: 10.2174/1389450117666160613101413

Opportunities of Bacterial Cellulose to Treat Epithelial Tissues open access plus

Volume: 20   Issue: 8
Pp: 808-822
Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch
DOI: 10.2174/1389450120666181129092144

Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective

Volume: 20   Issue: 5
Pp: 501-521
Surovi Saikia and Manobjyoti Bordoloi*
DOI: 10.2174/1389450119666181022153016

Established and In-trial GPCR Families in Clinical Trials: A Review for Target Selection

Volume: 20   Issue: 5
Pp: 522-539
Surovi Saikia, Manobjyoti Bordoloi* and Rajeev Sarmah
DOI: 10.2174/1389450120666181105152439

Potential Therapeutic Agents Against Par-4 Target for Cancer Treatment: Where Are We Going?

Volume: 20   Issue: 6
Pp: 635-654
Renata Virgínia Cavalcanti Santos, Wanessa Layssa Batista de Sena, Flaviana Alves dos Santos, Antônio Felix da Silva Filho, Marina Galdino da Rocha Pitta, Maira Galdino da Rocha Pitta, Moacyr Barreto de Melo Rego and Michelly Cristiny Pereira*
DOI: 10.2174/1389450120666181126122440

ROS-Mediated DNA Methylation Pattern Alterations in Carcinogenesis promotion: free to download

Volume: 16   Issue: 1
Pp: 13-19
Qihan Wu and Xiaohua Ni
DOI: 10.2174/1389450116666150113121054

Investigational Hypoxia-Activated Prodrugs: Making Sense of Future Development

Volume: 20   Issue: 6
Pp: 668-678
Min-Xia Su, Le-Le Zhang, Zhang-Jian Huang, Jia-Jie Shi and Jin-Jian Lu*
DOI: 10.2174/1389450120666181123122406