Current Drug Targets


Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556


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Most Accessed Articles

Cytochrome P450 Structure, Function and Clinical Significance: A Review promotion: free to download

Volume: 19   Issue: 1
Pp: 38-54
Palrasu Manikandan and Siddavaram Nagini*
DOI: 10.2174/1389450118666170125144557

PARP Inhibitor Drugs in the Treatment of Breast, Ovarian, Prostate and Pancreatic Cancers: An Update of Clinical Trials promotion: free to download

Volume: 19   Issue: 1
Pp: 21-37
Dalia Kamel*, Christopher Gray, Jagdeep Singh Walia and Vikaash Kumar*
DOI: 10.2174/1389450118666170711151518

Loss of the Tumor Suppressor HACE1 Contributes to Cancer Progression

Volume: 20   Issue: 10
Pp: 1018-1028
Jun-Chen Li, Xing Chang, Yang Chen, Xin-Zhe Li, Xiang-Lian Zhang, Shi-Ming Yang, Chang-Jiang Hu* and Hao Zhang*
DOI: 10.2174/1389450120666190227184654

Anti-TNF and Pouch Surgery for Ulcerative Colitis: The Ones who Blame for More Complications?

Volume: 20   Issue: 13
Pp: 1349-1355
G. Bislenghi*, M. Ferrante and A. D’Hoore
DOI: 10.2174/1389450120666190328153200

Age-related Macular Degeneration: Current Knowledge of Zinc Metalloproteinases Involvement

Volume: 20   Issue: 9
Pp: 903-918
Francesca Liva, Doretta Cuffaro, Elisa Nuti, Susanna Nencetti, Elisabetta Orlandini, Giovanni Vozzi and Armando Rossello*
DOI: 10.2174/1389450120666190122114857

High Mobility Group Box-1 (HMGB1): A Potential Target in Therapeutics

Volume: 20   Issue: 14
Pp: 1474-1485
Eyaldeva C. Vijayakumar, Lokesh Kumar Bhatt* and Kedar S. Prabhavalkar
DOI: 10.2174/1389450120666190618125100

Significance and Mechanisms of P-glycoprotein in Central Nervous System Diseases

Volume: 20   Issue: 11
Pp: 1141-1155
Liangliang Huang, Binbin Li, Xiang Li, Ge Liu, Rui Liu, Jia Guo, Baohui Xu, Yunman Li* and Weirong Fang*
DOI: 10.2174/1389450120666190308144448

Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective

Volume: 20   Issue: 5
Pp: 501-521
Surovi Saikia and Manobjyoti Bordoloi*
DOI: 10.2174/1389450119666181022153016

The Use of Naltrexone in Dermatology. Current Evidence and Future Directions

Volume: 20   Issue: 10
Pp: 1058-1067
Mariusz Sikora*, Adriana Rakowska, Małgorzata Olszewska and Lidia Rudnicka
DOI: 10.2174/1389450120666190318121122

Nano Drug Delivery in Treatment of Oral Cancer, A Review of the Literature

Volume: 20   Issue: 10
Pp: 1008-1017
Vandita Kakkar*, Manoj Kumar Verma, Komal Saini and Indu Pal Kaur
DOI: 10.2174/1389450120666190319125734